1F0J
 
 | | CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 4B2B | | 分子名称: | ARSENIC, MAGNESIUM ION, PHOSPHODIESTERASE 4B, ... | | 著者 | Xu, R.X, Hassell, A.M, Vanderwall, D, Lambert, M.H, Holmes, W.D, Luther, M.A, Rocque, W.J, Milburn, M.V, Zhao, Y, Ke, H, Nolte, R.T. | | 登録日 | 2000-05-16 | | 公開日 | 2000-07-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity.
Science, 288, 2000
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8WFJ
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8WFK
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8WFL
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8WFI
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2FO3
 | | Plasmodium vivax ubiquitin conjugating enzyme E2 | | 分子名称: | Ubiquitin-conjugating enzyme | | 著者 | Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Qiu, W, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-12 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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4XWW
 | | Crystal structure of RNase J complexed with RNA | | 分子名称: | DR2417, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y. | | 登録日 | 2015-01-29 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
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2FU0
 | | Plasmodium falciparum cyclophilin PFE0505w putative cyclosporin-binding domain | | 分子名称: | cyclophilin, putative | | 著者 | Dong, A, Lew, J, Sundararajan, E, Zhao, Y, Wasney, G, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-25 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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2GHI
 | | Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2 | | 分子名称: | SULFATE ION, transport protein | | 著者 | Dong, A, Gao, M, Choe, J, Zhao, Y, Lew, J, Wasney, G, Alam, Z, Melone, M, Kozieradzki, I, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) | | 登録日 | 2006-03-27 | | 公開日 | 2006-04-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
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3CC9
 | | Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate | | 分子名称: | GERANYLGERANYL DIPHOSPHATE, Putative farnesyl pyrophosphate synthase, SODIUM ION | | 著者 | Wernimont, A.K, Dunford, J, Lew, J, Zhao, Y, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) | | 登録日 | 2008-02-25 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate.
To be Published
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4UIS
 | | The cryoEM structure of human gamma-Secretase complex | | 分子名称: | GAMMA-SECRETASE, LYSOZYME | | 著者 | Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y. | | 登録日 | 2015-04-03 | | 公開日 | 2015-06-10 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2Q9Z
 | | Trichodiene synthase: Complex with inorganic pyrophosphate resulting from the reaction with 2-fluorofarnesyl diphosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Vedula, L.S, Zhao, Y, Coates, R.M, Koyama, T, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-06-14 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Exploring biosynthetic diversity with trichodiene synthase.
Arch.Biochem.Biophys., 466, 2007
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2R0J
 | | Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum | | 分子名称: | Ubiquitin carrier protein | | 著者 | Wernimont, A.K, Lew, J, Lin, Y.H, Hassanali, A, Kozieradzki, I, Zhao, Y, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-08-20 | | 公開日 | 2007-09-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum.
To be Published
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4F5Y
 | | Crystal structure of human STING CTD complex with C-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | | 著者 | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | | 登録日 | 2012-05-13 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.396 Å) | | 主引用文献 | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
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4F5W
 | | Crystal structure of ligand free human STING CTD | | 分子名称: | CALCIUM ION, Transmembrane protein 173 | | 著者 | Gu, L, Shang, G, Zhu, D, Li, N, Zhang, J, Zhu, C, Lu, D, Liu, C, Yu, Q, Zhao, Y, Xu, S. | | 登録日 | 2012-05-13 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Nat.Struct.Mol.Biol., 19, 2012
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3TO8
 | | Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L) | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Heterogeneous nuclear ribonucleoprotein L, ... | | 著者 | Zhang, W.J, Zeng, F.X, Liu, Y.W, Zhao, Y, Niu, L.W, Teng, M.K, Li, X. | | 登録日 | 2011-09-04 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L)
To be Published
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8HMB
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with benidipine (BEN) | | 分子名称: | (3R)-1-benzylpiperidin-3-yl methyl (2R,3R,4R,5R,6S)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-12-02 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8HMA
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with tetrandrine (TET) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-12-02 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8HLP
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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4X2A
 | | Crystal structure of mouse glyoxalase I complexed with baicalein | | 分子名称: | 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Lactoylglutathione lyase, ZINC ION | | 著者 | Zhang, H, Zhai, J, Zhang, L, Li, C, Zhao, Y, Hu, X. | | 登録日 | 2014-11-26 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis.
Curr Top Med Chem, 16, 2016
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2QT5
 | | Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide | | 分子名称: | (ASN)(ASN)(LEU)(GLN)(ASP)(GLY)(THR)(GLU)(VAL), 1,2-ETHANEDIOL, ACETIC ACID, ... | | 著者 | Long, J, Wei, Z, Feng, W, Zhao, Y, Zhang, M. | | 登録日 | 2007-08-01 | | 公開日 | 2008-06-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.
J.Mol.Biol., 375, 2008
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4N9L
 | | crystal structure of beta-lactamse PenP_E166S in complex with meropenem | | 分子名称: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase | | 著者 | Pan, X, Wong, W, Zhao, Y. | | 登録日 | 2013-10-21 | | 公開日 | 2014-09-10 | | 最終更新日 | 2022-02-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
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4N9K
 | | crystal structure of beta-lactamse PenP_E166S in complex with cephaloridine | | 分子名称: | 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase | | 著者 | Pan, X, Wong, W, Zhao, Y. | | 登録日 | 2013-10-21 | | 公開日 | 2014-09-10 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
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4N92
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8HLG
 | | Crystal structure of MoaE | | 分子名称: | Molybdenum cofactor biosynthesis protein D/E, SULFATE ION | | 著者 | Cai, J, Zhao, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MoaE Is Involved in Response to Oxidative Stress in Deinococcus radiodurans.
Int J Mol Sci, 24, 2023
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