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PDB: 1 件

3BCJ
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Crystal structure of Aldose Reductase complexed with 2S4R (Stereoisomer of Fidarestat, 2S4S) at 0.78 A
分子名称: (2S,4R)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldose reductase, CITRIC ACID, ...
著者Zhao, H.T, El-Kabbani, O.
登録日2007-11-13
公開日2008-04-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (0.78 Å)
主引用文献Unusual Binding Mode of the 2S4R Stereoisomer of the Potent Aldose Reductase Cyclic Imide Inhibitor Fidarestat (2S4S) in the 15 K Crystal Structure of the Ternary Complex Refined at 0.78 A Resolution: Implications for the Inhibition Mechanism
J.Med.Chem., 51, 2008

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件を2024-07-03に公開中

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