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PDB: 1273 件

5ADY
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Cryo-EM structures of the 50S ribosome subunit bound with HflX
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
著者Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
登録日2015-08-25
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
5WMG
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N-terminal bromodomain of BRD4 in complex with OTX-015
分子名称: 1,2-ETHANEDIOL, 4-{6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1S)-1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl}benzoic acid, Bromodomain-containing protein 4
著者Zhang, Y.
登録日2017-07-28
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Cancer Discov, 8, 2018
5WMD
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N-terminal bromodomain of BRD4 in complex with OTX-015
分子名称: 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)acetamide, Bromodomain-containing protein 4
著者Zhang, Y.
登録日2017-07-28
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Cancer Discov, 8, 2018
6LCY
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Crystal structure of Synaptotagmin-7 C2B in complex with IP6
分子名称: INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7
著者Zhang, Y, Zhang, X, Rao, F, Wang, C.
登録日2019-11-20
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Nat Metab, 3, 2021
6XNZ
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Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex
分子名称: 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ...
著者Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
登録日2020-07-05
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
6XNY
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Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Paired-Form)
分子名称: 12RSS integration strand (55-mer), 12RSS signal DNA top strand (34-mer), 23RSS integration strand (66-mer), ...
著者Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
登録日2020-07-05
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
4G7O
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Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA
分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ...
著者Zhang, Y, Ebright, R.H.
登録日2012-07-20
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.993 Å)
主引用文献Structural basis of transcription initiation.
Science, 338, 2012
4G7Z
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Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1
分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2012-07-20
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.815 Å)
主引用文献Structural basis of transcription initiation.
Science, 338, 2012
1MEN
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BU of 1men by Molmil
complex structure of human GAR Tfase and substrate beta-GAR
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, Phosphoribosylglycinamide formyltransferase
著者Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A.
登録日2002-08-08
公開日2002-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
4GKU
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Crystal structure of beta lactamase in PET-15B
分子名称: Beta-lactamase TEM
著者Zhang, Y, Cao, C.
登録日2012-08-13
公開日2012-10-10
実験手法X-RAY DIFFRACTION (1.915 Å)
主引用文献Crystal structure of beta lactamase in PET-15B
To be published
6E86
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BU of 6e86 by Molmil
Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide
分子名称: H3K4ac, ZINC ION, ZZ-type zinc finger-containing protein 3
著者Zhang, Y, Kutateladze, T.G.
登録日2018-07-27
公開日2018-09-19
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation.
Nat Commun, 9, 2018
5VTM
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BU of 5vtm by Molmil
The crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa
分子名称: CALCIUM ION, Type II secretion system protein I, Type II secretion system protein J, ...
著者Zhang, Y, Jia, Z.
登録日2017-05-17
公開日2018-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.041 Å)
主引用文献Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
PLoS Pathog., 14, 2018
3ZEE
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BU of 3zee by Molmil
Electron cyro-microscopy helical reconstruction of Par-3 N terminal domain
分子名称: PARTITIONING DEFECTIVE 3 HOMOLOG
著者Zhang, Y, Wang, W, Chen, J, Zhang, K, Gao, F, Gong, W, Zhang, M, Sun, F, Feng, W.
登録日2012-12-05
公開日2013-10-16
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain.
Structure, 21, 2013
2GHQ
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BU of 2ghq by Molmil
CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
著者Zhang, Y, Noel, J.P.
登録日2006-03-27
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
2GHT
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CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
著者Zhang, Y, Noel, J.P.
登録日2006-03-27
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
6M0W
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BU of 6m0w by Molmil
Crystal structure of Streptococcus thermophilus Cas9 in complex with the AGAA PAM
分子名称: CRISPR-associated endonuclease Cas9 1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*GP*AP*AP*GP*C)-3'), ...
著者Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q.
登録日2020-02-23
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
3LBS
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BU of 3lbs by Molmil
Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound form)
分子名称: Maltose-binding periplasmic protein, Renin receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Zhang, Y, Garavito, R.M.
登録日2010-01-08
公開日2011-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein.
Biochem.Biophys.Res.Commun., 407, 2011
5HYN
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BU of 5hyn by Molmil
Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide
分子名称: H3K27M, Histone-lysine N-methyltransferase EZH2, JARID2 K116me3, ...
著者Zhang, Y, Justin, N, Wilson, J.R, Gamblin, S.J.
登録日2016-02-01
公開日2016-05-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016
1N6G
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BU of 1n6g by Molmil
The structure of immature Dengue-2 prM particles
分子名称: major envelope protein E
著者Zhang, Y, Corver, J, Chipman, P.R, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G.
登録日2002-11-10
公開日2003-06-03
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (16 Å)
主引用文献Structures of Immature flavivirus particles
EMBO J., 22, 2003
1NA4
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The structure of immature Yellow Fever virus particle
分子名称: major envelope protein E
著者Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G.
登録日2002-11-26
公開日2003-12-09
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY
主引用文献Structures of immature flavivirus particles
EMBO J., 22, 2003
6XRQ
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Structural descriptions of ligand interactions to DNA and RNA quadruplexes folded from the non-coding region of Pseudorabies virus
分子名称: 2,7-bis[3-(morpholin-4-yl)propyl]-4,9-bis{[3-(morpholin-4-yl)propyl]amino}benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, POTASSIUM ION, RNA (5' GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A-3')
著者Zhang, Y.S, Parkinson, G.N, Wei, D.G.
登録日2020-07-13
公開日2021-07-28
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of Pseudorabies virus.
Biochimie, 2024
2R86
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Crystal structure of PurP from Pyrococcus furiosus complexed with ATP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-10
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R7K
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Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMPPCP and AICAR
分子名称: 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, CHLORIDE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-09
公開日2007-12-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R7M
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Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMP
分子名称: 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-09
公開日2007-12-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R84
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Crystal structure of PurP from Pyrococcus furiosus complexed with AMP and AICAR
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-10
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008

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