7AQA
 
 | | Pseudomonas stutzeri nitrous oxide reductase mutant, H382A | | 分子名称: | (dicuprio-$l^{3}-sulfanyl)-sulfanyl-copper, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. | | 登録日 | 2020-10-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | | 主引用文献 | A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase.
Chem Sci, 12, 2021
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7AQ0
 | | Pseudomonas stutzeri nitrous oxide reductase mutant, D576A/S550A | | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. | | 登録日 | 2020-10-20 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.584 Å) | | 主引用文献 | Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
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7AQ9
 | | Pseudomonas stutzeri nitrous oxide reductase mutant, H583W | | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. | | 登録日 | 2020-10-20 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.585 Å) | | 主引用文献 | Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
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7AQ2
 | | Pseudomonas stutzeri nitrous oxide reductase mutant, H583A | | 分子名称: | (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. | | 登録日 | 2020-10-20 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.683 Å) | | 主引用文献 | Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
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4J0X
 | | Structure of Rrp9 | | 分子名称: | Ribosomal RNA-processing protein 9 | | 著者 | Zhang, L, Lin, J, Ye, K. | | 登録日 | 2013-01-31 | | 公開日 | 2013-06-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Structural and functional analysis of the U3 snoRNA binding protein Rrp9.
Rna, 19, 2013
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4J0W
 | | Structure of U3-55K | | 分子名称: | U3 small nucleolar RNA-interacting protein 2 | | 著者 | Zhang, L, Lin, J, Ye, K. | | 登録日 | 2013-01-31 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and functional analysis of the U3 snoRNA binding protein Rrp9.
Rna, 19, 2013
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7BIP
 | | Crystal structure of monooxygenase RslO1 from Streptomyces bottropensis | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Zhang, L, Zuo, C, Bechthold, A, Einsle, O. | | 登録日 | 2021-01-12 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
Mol Biotechnol., 63, 2021
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4JEK
 | | Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | | 分子名称: | Dibenzothiophene desulfurization enzyme C | | 著者 | Zhang, L, Duan, X.L, Zhou, D.M, Li, X. | | 登録日 | 2013-02-27 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Acta Crystallogr.,Sect.F, 69, 2013
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7BIO
 | | Crystal structure of monooxygenase RslO4 from Streptomyces bottropensis | | 分子名称: | ACETATE ION, ETHANOL, Monooxygenase/putative anthronoxygenase, ... | | 著者 | Zhang, L, Zuo, C, Alali, A, Bechthold, A, Einsle, O. | | 登録日 | 2021-01-12 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | | 主引用文献 | Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
Mol Biotechnol., 63, 2021
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7C5F
 | | Crystal Structure of Glyceraldehyde-3-phosphate dehydrogenase1 from Escherichia coli at 1.88 Angstrom resolution | | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | | 著者 | Zhang, L, Liu, M.R, Yao, Y.C, Bostrom, I.K, Wang, Y.D, Chen, A.Q, Li, J.X, Gu, S.H, Ji, C.N. | | 登録日 | 2020-05-20 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Characterization and structure of glyceraldehyde-3-phosphate dehydrogenase type 1 from Escherichia coli.
Acta Crystallogr.,Sect.F, 76, 2020
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4NXL
 | | Dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | | 分子名称: | DszC | | 著者 | Zhang, L, Duan, X, Li, X, Rao, Z. | | 登録日 | 2013-12-09 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into the stabilization of active, tetrameric DszC by its C-terminus.
Proteins, 82, 2014
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7WE6
 | | Structure of Csy-AcrIF24-dsDNA | | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | | 著者 | Zhang, L, Feng, Y. | | 登録日 | 2021-12-22 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24.
Nat Commun, 13, 2022
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7ELN
 | | Structure of Csy-AcrIF24-dsDNA | | 分子名称: | 54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ... | | 著者 | Zhang, L, Feng, Y. | | 登録日 | 2021-04-12 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24.
Nat Commun, 13, 2022
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7ELM
 | | Structure of Csy-AcrIF24 | | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | | 著者 | Zhang, L, Feng, Y. | | 登録日 | 2021-04-12 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24.
Nat Commun, 13, 2022
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8JU8
 | | de novo designed protein | | 分子名称: | de novo designed protein | | 著者 | Zhang, L. | | 登録日 | 2023-06-25 | | 公開日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | de novo designed Rossmann fold protein
To Be Published
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5XD6
 | | CARK1 phosphorylates ABA receptors | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein kinase superfamily protein | | 著者 | Zhang, L, Lou, Z. | | 登録日 | 2017-03-27 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | CARK1 phosphorylates ABA receptors
To Be Published
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6B8F
 | | Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid | | 分子名称: | CALCIUM ION, FE (III) ION, Ferritin heavy chain | | 著者 | Zhang, L, Bailey, J.B, Subramanian, R, Tezcan, F.A. | | 登録日 | 2017-10-07 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.
Nature, 557, 2018
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6B8G
 | | Twice-Contracted Human Heavy-Chain Ferritin Crystal-Hydrogel Hybrid | | 分子名称: | CALCIUM ION, FE (III) ION, Ferritin heavy chain | | 著者 | Zhang, L, Bailey, J.B, Subramanian, R, Tezcan, F.A. | | 登録日 | 2017-10-07 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks.
Nature, 557, 2018
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7ZJG
 | | Probenecid | | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | | 著者 | Zhang, L, Gourdon, P, Zygmunt, P.M. | | 登録日 | 2022-04-11 | | 公開日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
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7ZJI
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7ZJD
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7ZJH
 | | TRPV2-C16+Pro-2 | | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | | 著者 | Zhang, L, Gourdon, P, Zygmunt, P.M. | | 登録日 | 2022-04-11 | | 公開日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
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7ZJE
 | | C16-2 | | 分子名称: | Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein | | 著者 | Zhang, L, Gourdon, P, Zygmunt, P.M. | | 登録日 | 2022-04-10 | | 公開日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
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7XMK
 | | Crystal structure of human RIPK1 kinase domain in complex with compound SKLB923 | | 分子名称: | 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | | 著者 | Zhang, L, Wang, Y, Li, Y, Yang, S. | | 登録日 | 2022-04-26 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.376 Å) | | 主引用文献 | From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases.
J.Med.Chem., 67, 2024
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7YDX
 | | Crystal structure of human RIPK1 kinase domain in complex with compound RI-962 | | 分子名称: | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-phenylethyl]indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | | 著者 | Zhang, L, Wang, Y, Li, Y, Wu, C, Luo, X, Wang, T, Lei, J, Yang, S. | | 登録日 | 2022-07-04 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.642 Å) | | 主引用文献 | Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
Nat Commun, 13, 2022
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