1ORH
 
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1DYC
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6AHF
 | | CryoEM Reconstruction of Hsp104 N728A Hexamer | | 分子名称: | Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Zhang, X, Zhang, L, Zhang, S. | | 登録日 | 2018-08-17 | | 公開日 | 2019-02-13 | | 最終更新日 | 2019-04-10 | | 実験手法 | ELECTRON MICROSCOPY (6.78 Å) | | 主引用文献 | Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.
J. Biol. Chem., 294, 2019
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6IWI
 | | Crystal structure of PDE5A in complex with a novel inhibitor | | 分子名称: | MAGNESIUM ION, N-[3-(4,5-diethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-4-propoxyphenyl]-2-(4-methylpiperazin-1-yl)acetamide, ZINC ION, ... | | 著者 | Zhang, X.L, Xu, Y.C. | | 登録日 | 2018-12-05 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.155 Å) | | 主引用文献 | Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension.
J.Med.Chem., 62, 2019
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1DYD
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6J4M
 | | Thermal treated soybean seed H-2 ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Zhang, X, Zang, J, Chen, H, Zhou, K, Zhao, G. | | 登録日 | 2019-01-09 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface.
Rsc Adv, 9, 2019
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3IYK
 | | Bluetongue virus structure reveals a sialic acid binding domain, amphipathic helices and a central coiled coil in the outer capsid proteins | | 分子名称: | 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, VP2, VP5 | | 著者 | Zhang, X, Boyce, M, Bhattacharya, B, Zhang, X, Schein, S, Roy, P, Zhou, Z.H. | | 登録日 | 2010-01-25 | | 公開日 | 2010-04-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
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169L
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168L
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3KLX
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170L
 | | PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME | | 分子名称: | BETA-MERCAPTOETHANOL, T4 LYSOZYME | | 著者 | Zhang, X.-J, Weaver, L.H, Wozniak, A, Matthews, B.W. | | 登録日 | 1995-03-24 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
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1DYB
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3KL1
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1OR8
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1DYE
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1DYA
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1F3L
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7YC8
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the first-step self-splicing | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA (388-MER) | | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | 登録日 | 2022-07-01 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YCG
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the first-step self-splicing | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | 登録日 | 2022-07-01 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YCI
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ... | | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | 登録日 | 2022-07-01 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YCH
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | | 著者 | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | 登録日 | 2022-07-01 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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6IMR
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | (1S)-1-[3-(1H-indol-3-yl)propyl]-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | | 著者 | Zhang, X.L, Su, H.X, Xu, Y.C. | | 登録日 | 2018-10-23 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.503 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
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4GJT
 | | complex structure of nectin-4 bound to MV-H | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4 | | 著者 | Zhang, X, Lu, G, Qi, J, Li, Y, He, Y, Xu, X, Shi, J, Zhang, C, Yan, J, Gao, G.F. | | 登録日 | 2012-08-10 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1001 Å) | | 主引用文献 | Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
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4DSB
 | | Complex Structure of Abscisic Acid Receptor PYL3 with (+)-ABA in Spacegroup of I 212121 at 2.70A | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3 | | 著者 | Zhang, X, Zhang, Q, Chen, Z. | | 登録日 | 2012-02-18 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
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8H0Z
 | | Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-122 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | | 登録日 | 2022-09-30 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.
Life Sci Alliance, 6, 2023
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