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PDB: 1 件

6UYA
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BU of 6uya by Molmil
Crystal structure of Compound 19 bound to IRAK4
分子名称: Interleukin-1 receptor-associated kinase 4, N-{2-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-6-(morpholin-4-yl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide, SULFATE ION
著者Kiefer, J.R, Bryan, M.C, Lupardus, P.J, Zarrin, A.A, Rajapaksa, N.S, Gobbi, A, Drobnick, J, Kolesnikov, A, Liang, J, Do, S.
登録日2019-11-12
公開日2019-11-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity.
Acs Med.Chem.Lett., 11, 2020

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件を2024-11-06に公開中

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