3QN7
| Potent and selective bicyclic peptide inhibitor (UK18) of human urokinase-type plasminogen activator(uPA) | Descriptor: | 1,3,5-tris(bromomethyl)benzene, Bicyclic peptide inhibitor, Urokinase-type plasminogen activator | Authors: | Angelini, A, Cendron, L, Touati, J, Winter, G, Zanotti, G, Heinis, C. | Deposit date: | 2011-02-08 | Release date: | 2012-02-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bicyclic peptide inhibitor reveals large contact interface with a protease target Acs Chem.Biol., 7, 2012
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3IWV
| Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP) | Descriptor: | 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | Deposit date: | 2009-09-03 | Release date: | 2010-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
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6Z05
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1ZOF
| Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter Pylori | Descriptor: | alkyl hydroperoxide-reductase | Authors: | Papinutto, E, Windle, H.J, Cendron, L, Battistutta, R, Kelleher, D, Zanotti, G. | Deposit date: | 2005-05-13 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori. Biochim.Biophys.Acta, 1753, 2005
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6R66
| Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | Descriptor: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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6R67
| Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | Descriptor: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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6R68
| Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue | Descriptor: | (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | Deposit date: | 2019-03-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin. J.Struct.Biol., 208, 2019
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3QQ5
| Crystal structure of the [FeFe]-hydrogenase maturation protein HydF | Descriptor: | Small GTP-binding protein | Authors: | Cendron, L, Berto, P, D'Adamo, S, Vallese, F, Govoni, C, Posewitz, M.C, Giacometti, G.M, Costantini, P, Zanotti, G. | Deposit date: | 2011-02-15 | Release date: | 2011-11-16 | Last modified: | 2012-01-11 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Crystal Structure of HydF Scaffold Protein Provides Insights into [FeFe]-Hydrogenase Maturation. J.Biol.Chem., 286, 2011
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1ZOH
| Crystal structure of protein kinase CK2 in complex with TBB-derivatives inhibitors | Descriptor: | 1,2-ETHANEDIOL, 5,6,7,8-TETRABROMO-1-METHYL-2,3-DIHYDRO-1H-IMIDAZO[1,2-A]BENZIMIDAZOLE, CHLORIDE ION, ... | Authors: | Battistutta, R, Mazzorana, M, Sarno, S, Kazimierczuk, Z, Zanotti, G, Pinna, L.A. | Deposit date: | 2005-05-13 | Release date: | 2005-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem.Biol., 12, 2005
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3SXP
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2ALG
| Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens | Descriptor: | HEPTANE, HEXAETHYLENE GLYCOL, LAURIC ACID, ... | Authors: | Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, J, Zanotti, G. | Deposit date: | 2005-08-05 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens J.Mol.Biol., 356, 2006
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1TU5
| Crystal structure of bovine plasma copper-containing amine oxidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lunelli, M, Di Paolo, M.L, Biadene, M, Calderone, V, Scarpa, M, Battistutta, R, Rigo, A, Zanotti, G. | Deposit date: | 2004-06-24 | Release date: | 2005-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of amine oxidase from bovine serum. J.Mol.Biol., 346, 2005
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2O70
| Structure of OHCU decarboxylase from zebrafish | Descriptor: | OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-09 | Release date: | 2007-04-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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2O73
| Structure of OHCU decarboxylase in complex with allantoin | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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2O74
| Structure of OHCU decarboxylase in complex with guanine | Descriptor: | GUANINE, OHCU decarboxylase | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation. J.Biol.Chem., 282, 2007
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3QBU
| Crystal structure of putative peptidoglycan deactelyase (HP0310) from Helicobacter pylori | Descriptor: | Putative uncharacterized protein, ZINC ION | Authors: | Shaik, M.M, Cendron, L, Percudani, R, Zanotti, G. | Deposit date: | 2011-01-14 | Release date: | 2011-05-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5701 Å) | Cite: | The Structure of Helicobacter pylori HP0310 Reveals an Atypical Peptidoglycan Deacetylase. Plos One, 6, 2011
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2RD3
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3CWY
| Structure of CagD from H. pylori pathogenicity island crystallized in the presence of Cu(II) ions | Descriptor: | COPPER (II) ION, protein CagD | Authors: | Cendron, L, Zanotti, G, Angelini, A, Barison, N, Couturier, M, Stein, M. | Deposit date: | 2008-04-23 | Release date: | 2008-12-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion. J.Mol.Biol., 386, 2009
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5AKS
| Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-3-O- glucuronide | Descriptor: | DIMETHYL SULFOXIDE, Resveratrol-3-O-glucuronide, SULFATE ION, ... | Authors: | Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-05 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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4ZZK
| Crystal structure of truncated FlgD (monoclinic form) from the human pathogen Helicobacter pylori | Descriptor: | Basal-body rod modification protein FlgD | Authors: | Pulic, I, Cendron, L, Salamina, M, Matkovic-Calogovic, D, Zanotti, G. | Deposit date: | 2015-05-22 | Release date: | 2016-02-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of truncated FlgD from the human pathogen Helicobacter pylori. J.Struct.Biol., 194, 2016
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2PZH
| YbgC thioesterase (Hp0496) from Helicobacter pylori | Descriptor: | Hypothetical protein HP_0496 | Authors: | Angelini, A, Cendron, L, Goncalves, S, Zanotti, G, Terradot, L. | Deposit date: | 2007-05-18 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and enzymatic characterization of HP0496, a YbgC thioesterase from Helicobacter pylori. Proteins, 72, 2008
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5AKT
| Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-4'-O- glucuronide | Descriptor: | Resveratrol-4'-O-glucuronide, SULFATE ION, TRANSTHYRETIN | Authors: | Florio, P, Folli, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-05 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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5AL0
| Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-3-O-sulfate | Descriptor: | DIMETHYL SULFOXIDE, RESVERATROL-3-O-SULFATE, SULFATE ION, ... | Authors: | Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. | Deposit date: | 2015-03-05 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.388 Å) | Cite: | Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
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1ZOG
| Crystal structure of protein kinase CK2 in complex with TBB-derivatives | Descriptor: | 4,5,6,7-TETRABROMO-2-(METHYLSULFANYL)-1H-BENZIMIDAZOLE, PROTEIN KINASE CK2, alpha SUBUNIT | Authors: | Battistutta, R, Mazzorana, M, Sarno, S, Kazimierczuk, Z, Zanotti, G, Pinna, L.A. | Deposit date: | 2005-05-13 | Release date: | 2005-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem.Biol., 12, 2005
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1ZOE
| Crystal structure of protein kinase CK2 in complex with TBB-derivatives inhibitors | Descriptor: | 4,5,6,7-TETRABROMO-N,N-DIMETHYL-1H-BENZIMIDAZOL-2-AMINE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Battistutta, R, Mazzorana, M, Sarno, S, Kazimierczuk, Z, Zanotti, G, Pinna, L.A. | Deposit date: | 2005-05-13 | Release date: | 2005-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem.Biol., 12, 2005
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