6XE4
| BTK Fluorocyclopropyl amide inhibitor, Compound 25 | 分子名称: | (1S,2S)-N-[2'-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-3'-(hydroxymethyl)-1-methyl-6-oxo[1,6-dihydro[3,4'-bipyridine]]-5-yl]-2-fluorocyclopropane-1-carboxamide, SULFATE ION, Tyrosine-protein kinase BTK | 著者 | Kiefer, J.R, Crawford, J.J, Lee, W, Eigenbrot, C, Yu, C. | 登録日 | 2020-06-11 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Stereochemical Differences in Fluorocyclopropyl Amides Enable Tuning of Btk Inhibition and Off-Target Activity. Acs Med.Chem.Lett., 11, 2020
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6XNP
| Crystal Structure of Human STING CTD complex with SR-717 | 分子名称: | 1,2-ETHANEDIOL, 4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid, GLYCEROL, ... | 著者 | Chin, E.N, Yu, C, Wolan, D.W, Petrassi, H.M, Lairson, L.L. | 登録日 | 2020-07-03 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science, 369, 2020
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8HQB
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8HPB
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7SIY
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1SQX
| Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A | 分子名称: | Cytochrome b, Cytochrome c1, heme protein, ... | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | 登録日 | 2004-03-21 | 公開日 | 2005-09-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol., 341, 2004
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8XC4
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1SQV
| Crystal Structure Analysis of Bovine Bc1 with UHDBT | 分子名称: | 6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE, Cytochrome b, Cytochrome c1, ... | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | 登録日 | 2004-03-19 | 公開日 | 2005-09-06 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol., 341, 2004
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1SQP
| Crystal Structure Analysis of Bovine Bc1 with Myxothiazol | 分子名称: | (2Z,6E)-7-{2'-[(2E,4E)-1,6-DIMETHYLHEPTA-2,4-DIENYL]-2,4'-BI-1,3-THIAZOL-4-YL}-3,5-DIMETHOXY-4-METHYLHEPTA-2,6-DIENAMID E, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | 登録日 | 2004-03-19 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol., 341, 2004
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1SQQ
| Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) | 分子名称: | Cytochrome b, Cytochrome c1, heme protein, ... | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | 登録日 | 2004-03-19 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol., 341, 2004
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1NTM
| Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom | 分子名称: | Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C, Xia, D. | 登録日 | 2003-01-30 | 公開日 | 2003-10-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry, 42, 2003
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1SQB
| Crystal Structure Analysis of Bovine Bc1 with Azoxystrobin | 分子名称: | Cytochrome b, Cytochrome c1, heme protein, ... | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | 登録日 | 2004-03-18 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex J.Mol.Biol., 341, 2004
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8H67
| type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution. | 分子名称: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | 著者 | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | 登録日 | 2022-10-15 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and genome editing of type I-B CRISPR-Cas. Nat Commun, 15, 2024
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1NTZ
| Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiquinone | 分子名称: | Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. | 登録日 | 2003-01-30 | 公開日 | 2003-10-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry, 42, 2003
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1NTK
| Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 | 分子名称: | Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. | 登録日 | 2003-01-30 | 公開日 | 2003-10-07 | 最終更新日 | 2016-03-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry, 42, 2003
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1NU1
| Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide (NQNO) | 分子名称: | 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE, Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. | 登録日 | 2003-01-30 | 公開日 | 2003-10-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry, 42, 2003
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6XNN
| Crystal Structure of Mouse STING CTD complex with SR-717. | 分子名称: | 4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid, Stimulator of interferon genes protein | 著者 | Chin, E.N, Yu, C, Wolan, D.W, Petrassi, H.M, Lairson, L.L. | 登録日 | 2020-07-03 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science, 369, 2020
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1QCR
| CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, UBIQUINOL CYTOCHROME C OXIDOREDUCTASE | 著者 | Xia, D, Yu, C.A, Kim, H, Xia, J.Z, Kachurin, A, Zhang, L, Yu, L, Deisenhofer, J. | 登録日 | 1997-05-17 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria. Science, 277, 1997
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8H7Q
| Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution | 分子名称: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | 著者 | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | 登録日 | 2022-10-20 | 公開日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution To Be Published
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1HP9
| kappa-Hefutoxins: a novel Class of Potassium Channel Toxins from Scorpion venom | 分子名称: | kappa-hefutoxin 1 | 著者 | Srinivasan, K.N, Sivaraja, V, Huys, I, Sasaki, T, Cheng, B, Kumar, T.K.S, Sato, K, Tytgat, J, Yu, C, Brian Chia, C.S, Ranganathan, S, Bowie, J.H, Kini, R.M, Gopalakrishnakone, P. | 登録日 | 2000-12-12 | 公開日 | 2002-08-28 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. J.Biol.Chem., 277, 2002
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1L0L
| structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone | 分子名称: | Cytochrome B, Cytochrome c1, heme protein, ... | 著者 | Gao, X, Wen, X, Yu, C.A, Esser, L, Tsao, S, Quinn, B, Zhang, L, Yu, L, Xia, D. | 登録日 | 2002-02-11 | 公開日 | 2003-04-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic-Aromatic Interaction in Inhibition Biochemistry, 41, 2003
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1L0N
| native structure of bovine mitochondrial cytochrome bc1 complex | 分子名称: | Cytochrome B, Cytochrome c1, heme protein, ... | 著者 | Gao, X, Wen, X, Yu, C.A, Esser, L, Tsao, S, Quinn, B, Zhang, L, Yu, L, Xia, D. | 登録日 | 2002-02-11 | 公開日 | 2003-04-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic-Aromatic Interaction in Inhibition Biochemistry, 41, 2003
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1CHV
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2X44
| Structure of a strand-swapped dimeric form of CTLA-4 | 分子名称: | CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 | 著者 | Sonnen, A.F.-P, Yu, C, Evans, E.J, Stuart, D.I, Davis, S.J, Gilbert, R.J.C. | 登録日 | 2010-01-28 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Domain Metastability: A Molecular Basis for Immunoglobulin Deposition? J.Mol.Biol., 399, 2010
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1FMM
| SOLUTION STRUCTURE OF NFGF-1 | 分子名称: | ACIDIC FIBROBLAST GROWTH FACTOR | 著者 | Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C. | 登録日 | 2000-08-18 | 公開日 | 2001-08-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens. J.Biol.Chem., 277, 2002
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