2LGH
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![BU of 2lgh by Molmil](/molmil-images/mine/2lgh) | Solution NMR structure of the AHSA1-like protein AHA_2358 from Aeromonas hydrophila refined with NH RDCs, Northeast Structural Genomics Consortium Target AhR99. | Descriptor: | Uncharacterized protein | Authors: | Ramelot, T.A, Yang, Y, Lee, H, Wang, D, Ciccosanti, C, Janjua, H, Nair, R, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-07-26 | Release date: | 2011-08-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the AHSA1-like protein AHA_2358 from Aeromonas
hydrophila refined with NH RDCs. Northeast Structural Genomics Consortium Target AhR99. To be Published
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2L09
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![BU of 2l09 by Molmil](/molmil-images/mine/2l09) | Solution NMR Structure of Protein asr4154 from Nostoc sp. PCC7120 Northeast Structural Genomics Consortium target ID NsR143 | Descriptor: | Asr4154 protein | Authors: | Feldmann, E.A, Yang, Y.A, Ramelot, T.A, Cort, J.R, Janjua, H, Ciccosanti, C.A, Lee, D, Acton, T.B, Xiao, R.A, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-30 | Release date: | 2010-08-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of asr4154 from Nostoc sp. PCC7120 Northeast Structural Genomics target ID Nsr143 To be Published
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2LNA
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![BU of 2lna by Molmil](/molmil-images/mine/2lna) | Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A | Descriptor: | AFG3-like protein 2 | Authors: | Ramelot, T.A, Yang, Y, Lee, H, Janua, H, Kohan, E, Shastry, R, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) | Deposit date: | 2011-12-20 | Release date: | 2012-01-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure and MD simulations of the AAA protease intermembrane space domain indicates peripheral membrane localization within the hexaoligomer. Febs Lett., 587, 2013
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2LPK
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![BU of 2lpk by Molmil](/molmil-images/mine/2lpk) | Solution NMR of the specialized apo-acyl carrier protein (RPA2022) from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR324 | Descriptor: | Specialized acyl carrier protein | Authors: | Ramelot, T.A, Rossi, P, Yang, Y, Lee, H, Ertekin, A, Wang, H, Ciccosanti, C, Kohan, E, Maglaqui, M, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-02-14 | Release date: | 2012-02-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations. Biochemistry, 51, 2012
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2LTE
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![BU of 2lte by Molmil](/molmil-images/mine/2lte) | Solution NMR structure of the specialized acyl carrier protein PA3334 (apo) from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaT415 | Descriptor: | Specialized acyl carrier protein | Authors: | Ramelot, T.A, Cort, J.R, Yang, Y, Garcia, M, Yee, A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-18 | Release date: | 2012-07-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the specialized acyl carrier protein PA3334 (apo) from
Pseudomonas aeruginosa. Northeast Structural Genomics Consortium Target
PaT415. To be Published
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2LCG
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![BU of 2lcg by Molmil](/molmil-images/mine/2lcg) | Solution NMR structure of protein Rmet_5065 from Ralstonia metallidurans, Northeast Structural Genomics Consortium Target CrR115 | Descriptor: | Uncharacterized protein | Authors: | Ramelot, T.A, Yang, Y, Wang, D, Ciccosanti, C, Janjua, H, Nair, R, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-04-29 | Release date: | 2011-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of protein Rmet_5065 from Ralstonia metallidurans.
Northeast Structural Genomics Consortium Target CrR115. To be Published
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2L8V
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![BU of 2l8v by Molmil](/molmil-images/mine/2l8v) | Solution NMR structure of the phycobilisome linker polypeptide domain of CpcC (20-153) from Thermosynechococcus elongatus, Northeast Structural Genomics Consortium Target TeR219A | Descriptor: | Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod | Authors: | Ramelot, T.A, Yang, Y, Cort, J.R, Lee, D, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-01-26 | Release date: | 2011-02-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the phycobilisome linker polypeptide domain of CpcC
(20-153) from Thermosynechococcus elongatus, Northeast Structural Genomics
Consortium Target TeR219A To be Published
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2L06
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![BU of 2l06 by Molmil](/molmil-images/mine/2l06) | Solution NMR structure of the PBS linker polypeptide domain (fragment 254-400) of phycobilisome linker protein ApcE from Synechocystis sp. PCC 6803. Northeast Structural Genomics Consortium Target SgR209C | Descriptor: | Phycobilisome LCM core-membrane linker polypeptide | Authors: | Ramelot, T.A, Yang, Y, Cort, J.R, Hamilton, K, Ciccosanti, C, Lee, D, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-30 | Release date: | 2010-08-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the PBS linker polypeptide domain of phycobilisome
linker protein apcE from Synechocystis sp. Northeast Structural Genomics Consortium
Target SgR209C To be Published
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2LL8
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![BU of 2ll8 by Molmil](/molmil-images/mine/2ll8) | Solution NMR structure of the specialized holo-acyl carrier protein RPA2022 from Rhodopseudomonas palustris refined with NH RDCs, Northeast Structural Genomics Consortium Target RpR324 | Descriptor: | 4'-PHOSPHOPANTETHEINE, Specialized acyl carrier protein | Authors: | Ramelot, T.A, Ni, S, Rossi, P, Yang, Y, Wang, H, Ciccosanti, C, Maglaqui, M, Janjua, H, Nair, R, Roset, B, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-10-31 | Release date: | 2011-11-30 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations. Biochemistry, 51, 2012
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2L3B
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![BU of 2l3b by Molmil](/molmil-images/mine/2l3b) | Solution NMR structure of the BT_0084 lipoprotein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR376 | Descriptor: | Conserved protein found in conjugate transposon | Authors: | Ramelot, T.A, Yang, Y, Wang, D, Ciccosanti, C, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-09-10 | Release date: | 2010-11-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of BT_0084, a conjugative transposon lipoprotein from Bacteroides thetaiotamicron. Proteins, 80, 2012
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2LM3
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![BU of 2lm3 by Molmil](/molmil-images/mine/2lm3) | Structure of the rhesus monkey TRIM5alpha PRYSPRY domain | Descriptor: | Tripartite motif-containing protein 5 | Authors: | Biris, N, Yang, Y, Taylor, A.B, Tomashevski, A, Guo, M, Hart, P.J, Diaz-Griffero, F, Ivanov, D.N. | Deposit date: | 2011-11-21 | Release date: | 2012-08-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module. Proc.Natl.Acad.Sci.USA, 109, 2012
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2LEM
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![BU of 2lem by Molmil](/molmil-images/mine/2lem) | |
2MA9
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![BU of 2ma9 by Molmil](/molmil-images/mine/2ma9) | HIV-1 Vif SOCS-box and Elongin BC solution structure | Descriptor: | Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, Virion infectivity factor | Authors: | Lu, Z, Bergeron, J.R, Atkinson, R.A, Schaller, T, Veselkov, D.A, Oregioni, A, Yang, Y, Matthews, S.J, Malim, M.H, Sanderson, M.R. | Deposit date: | 2013-07-01 | Release date: | 2013-12-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction. OPEN BIOLOGY, 3, 2013
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2MA6
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![BU of 2ma6 by Molmil](/molmil-images/mine/2ma6) | Solution NMR Structure of the RING finger domain from the Kip1 ubiquitination-promoting E3 complex protein 1 (KPC1/RNF123) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8700A | Descriptor: | E3 ubiquitin-protein ligase RNF123, ZINC ION | Authors: | Ramelot, T.A, Yang, Y, Janjua, H, Kohan, E, Wang, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-06-28 | Release date: | 2013-07-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the RING finger domain from the Kip1 ubiquitination-promoting E3 complex protein 1 (KPC1/RNF123) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8700A To be Published
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7EI3
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![BU of 7ei3 by Molmil](/molmil-images/mine/7ei3) | |
7EI4
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![BU of 7ei4 by Molmil](/molmil-images/mine/7ei4) | Crystal structure of MasL in complex with a novel covalent inhibitor, collimonin C | Descriptor: | (6S,7R,9E)-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase | Authors: | Lin, C.C, Huang, K.F, Yang, Y.L. | Deposit date: | 2021-03-30 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors. Commun Biol, 5, 2022
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2LXU
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![BU of 2lxu by Molmil](/molmil-images/mine/2lxu) | Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A | Descriptor: | Heterogeneous nuclear ribonucleoprotein H | Authors: | Ramelot, T.A, Yang, Y, Pederson, K, Shastry, R, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-08-31 | Release date: | 2012-10-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A To be Published
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2MA5
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![BU of 2ma5 by Molmil](/molmil-images/mine/2ma5) | Solution NMR structure of PHD type Zinc finger domain of Lysine-specific demethylase 5B (PLU-1/JARID1B) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7375C | Descriptor: | Lysine-specific demethylase 5B, ZINC ION | Authors: | Hassan, F, Ramelot, T.A, Yang, Y, Cort, J.R, Janjua, H, Kohan, E, Lee, D, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-06-28 | Release date: | 2013-08-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of PHD type Zinc finger domain of Lysine-specific
demethylase 5B (PLU-1/JARID1B) from Homo sapiens, Northeast Structural
Genomics Consortium (NESG) Target HR7375C To be Published
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2LUZ
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![BU of 2luz by Molmil](/molmil-images/mine/2luz) | Solution NMR Structure of CalU16 from Micromonospora echinospora, Northeast Structural Genomics Consortium (NESG) Target MiR12 | Descriptor: | CalU16 | Authors: | Ramelot, T.A, Yang, Y, Lee, H, Pederson, K, Lee, D, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Wrobel, R.L, Bingman, C.A, Singh, S, Thorson, J.S, Prestegard, J.H, Montelione, G.T, Phillips Jr, G.N, Kennedy, M.A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-06-22 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19. Acs Chem.Biol., 9, 2014
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2MPV
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![BU of 2mpv by Molmil](/molmil-images/mine/2mpv) | Structural insight into host recognition and biofilm formation by aggregative adherence fimbriae of enteroaggregative Esherichia coli | Descriptor: | Major fimbrial subunit of aggregative adherence fimbria II AafA | Authors: | Matthews, S.J, Yang, Y, Berry, A.A, Pakharukova, N, Garnett, J.A, Lee, W, Cota, E, Liu, B, Roy, S, Tuittila, M, Marchant, J, Inman, K.G, Ruiz-Perez, F, Mandomando, I, Nataro, J.P, Zavialov, A.V. | Deposit date: | 2014-06-04 | Release date: | 2014-10-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli. Plos Pathog., 10, 2014
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7FEA
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![BU of 7fea by Molmil](/molmil-images/mine/7fea) | PY14 in complex with Col-D | Descriptor: | (6~{R},7~{R},9~{E})-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase | Authors: | Lin, C.C, Ko, T.P, Huang, K.F, Yang, Y.L. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors. Commun Biol, 5, 2022
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6K80
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![BU of 6k80 by Molmil](/molmil-images/mine/6k80) | Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Complex with CoA and Tryptophol | Descriptor: | 2-(1H-indol-3-yl)ethanol, ACETYL COENZYME *A, Dopamine N-acetyltransferase | Authors: | Wu, C.Y, Hu, I.C, Yang, Y.C, Cheng, H.C, Lyu, P.C. | Deposit date: | 2019-06-11 | Release date: | 2020-06-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase. Commun Biol, 3, 2020
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6A8G
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![BU of 6a8g by Molmil](/molmil-images/mine/6a8g) | The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5 | Descriptor: | PHOSPHATE ION, Urokinase-type plasminogen activator chain B, muPAin-1-IG | Authors: | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | Deposit date: | 2018-07-08 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J.Med.Chem., 62, 2019
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6A8N
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![BU of 6a8n by Molmil](/molmil-images/mine/6a8n) | The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5 | Descriptor: | CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B | Authors: | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | Deposit date: | 2018-07-09 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.489 Å) | Cite: | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J.Med.Chem., 62, 2019
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2QFJ
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![BU of 2qfj by Molmil](/molmil-images/mine/2qfj) | Crystal Structure of First Two RRM Domains of FIR Bound to ssDNA from a Portion of FUSE | Descriptor: | DNA (5'-D(*DTP*DCP*DGP*DGP*DGP*DAP*DTP*DTP*DTP*DTP*DTP*DTP*DAP*DTP*DTP*DTP*DTP*DGP*DTP*DGP*DTP*DTP*DAP*DTP*DT)-3'), FBP-interacting repressor | Authors: | Crichlow, G.V, Yang, Y, Fan, C, Lolis, E, Braddock, D. | Deposit date: | 2007-06-27 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition EMBO J., 27, 2007
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