4J9L
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![BU of 4j9l by Molmil](/molmil-images/mine/4j9l) | Human DNA polymerase eta-DNA ternary complex: misincorporation G opposite T after a C at the primer 3' end (CA/G) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA, DNA polymerase eta, ... | Authors: | Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. | Deposit date: | 2013-02-16 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
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4J9O
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![BU of 4j9o by Molmil](/molmil-images/mine/4j9o) | Human DNA polymerase eta-DNA ternary complex: primer extension after a T:G mispair | Descriptor: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*T*AP*CP*GP*TP*CP*AP*TP*G)-3'), ... | Authors: | Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. | Deposit date: | 2013-02-16 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
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4J9Q
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![BU of 4j9q by Molmil](/molmil-images/mine/4j9q) | Human DNA polymerase eta-DNA postinsertion binary complex with TG mispair | Descriptor: | DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), DNA (5'-D(*TP*C*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | Authors: | Zhao, Y, Gregory, M, Biertumpfel, C, Hua, Y, Hanaoka, F, Yang, W. | Deposit date: | 2013-02-16 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. Proc.Natl.Acad.Sci.USA, 110, 2013
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3RJX
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![BU of 3rjx by Molmil](/molmil-images/mine/3rjx) | Crystal Structure of Hyperthermophilic Endo-Beta-1,4-glucanase | Descriptor: | Endoglucanase FnCel5A | Authors: | Zheng, B.S, Yang, W, Zhao, X.Y, Wang, Y.G, Lou, Z.Y, Rao, Z.H, Feng, Y. | Deposit date: | 2011-04-15 | Release date: | 2011-12-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of hyperthermophilic endo-beta-1,4-glucanase: implications for catalytic mechanism and thermostability. J.Biol.Chem., 287, 2012
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6WYA
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![BU of 6wya by Molmil](/molmil-images/mine/6wya) | RTX (Reverse Transcription Xenopolymerase) in complex with a DNA duplex and dAMPNPP | Descriptor: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. | Deposit date: | 2020-05-12 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WYB
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![BU of 6wyb by Molmil](/molmil-images/mine/6wyb) | RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid | Descriptor: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA polymerase, ... | Authors: | Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. | Deposit date: | 2020-05-12 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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5XHZ
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![BU of 5xhz by Molmil](/molmil-images/mine/5xhz) | Crystal Structure Analysis of CIN85-SH3B in complex with ARAP1-P2 | Descriptor: | ACETATE ION, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, ... | Authors: | Liu, W, Yang, W. | Deposit date: | 2017-04-25 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.319 Å) | Cite: | Biochemical and Structural Studies of the Interaction between ARAP1 and CIN85. Biochemistry, 57, 2018
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4M3O
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![BU of 4m3o by Molmil](/molmil-images/mine/4m3o) | Crystal structure of K.lactis Rtr1 NTD | Descriptor: | KLLA0F12672p, ZINC ION | Authors: | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | Deposit date: | 2013-08-06 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD. J.Mol.Biol., 426, 2014
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5ZE2
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![BU of 5ze2 by Molmil](/molmil-images/mine/5ze2) | Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C | Descriptor: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (31-MER), ... | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | Deposit date: | 2018-02-25 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
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5ZDZ
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![BU of 5zdz by Molmil](/molmil-images/mine/5zdz) | Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+ | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DNA (30-MER), ... | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | Deposit date: | 2018-02-25 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
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1M7S
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![BU of 1m7s by Molmil](/molmil-images/mine/1m7s) | Crystal Structure Analysis of Catalase CatF of Pseudomonas syringae | Descriptor: | Catalase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Carpena, X, Soriano, M, Klotz, M.G, Duckworth, H.W, Donald, L.J, Melik-Adamyan, W, Fita, I, Loewen, P.C. | Deposit date: | 2002-07-22 | Release date: | 2002-08-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the Clade 1 catalase, CatF of Pseudomonas syringae, at 1.8 A resolution Proteins, 50, 2003
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5ZE0
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![BU of 5ze0 by Molmil](/molmil-images/mine/5ze0) | Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ | Descriptor: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ... | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | Deposit date: | 2018-02-25 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
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5ZE1
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![BU of 5ze1 by Molmil](/molmil-images/mine/5ze1) | Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C | Descriptor: | 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ... | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | Deposit date: | 2018-02-25 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
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2AGQ
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![BU of 2agq by Molmil](/molmil-images/mine/2agq) | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*(DOC))-3', 5'-D(*TP*CP*AP*TP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3', ... | Authors: | Ling, H, Yang, W. | Deposit date: | 2005-07-27 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
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2AOQ
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![BU of 2aoq by Molmil](/molmil-images/mine/2aoq) | Crystal structure of MutH-unmethylated DNA complex | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*AP*TP*CP*AP*TP*GP*C)-3', CALCIUM ION, DNA mismatch repair protein mutH | Authors: | Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. | Deposit date: | 2005-08-13 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol.Cell, 20, 2005
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2AGO
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![BU of 2ago by Molmil](/molmil-images/mine/2ago) | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... | Authors: | Ling, H, Yang, W. | Deposit date: | 2005-07-27 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
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2AGP
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![BU of 2agp by Molmil](/molmil-images/mine/2agp) | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*(DOC)-3'), ... | Authors: | Ling, H, Yang, W. | Deposit date: | 2005-07-27 | Release date: | 2005-09-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
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6CIL
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![BU of 6cil by Molmil](/molmil-images/mine/6cil) | PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+ | Descriptor: | High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ... | Authors: | Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. | Deposit date: | 2018-02-24 | Release date: | 2018-04-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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6CIJ
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![BU of 6cij by Molmil](/molmil-images/mine/6cij) | Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | Authors: | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | Deposit date: | 2018-02-24 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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6CIK
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![BU of 6cik by Molmil](/molmil-images/mine/6cik) | Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+ | Descriptor: | DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 12RSS substrate forward strand, ... | Authors: | Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. | Deposit date: | 2018-02-24 | Release date: | 2018-04-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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6CG0
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![BU of 6cg0 by Molmil](/molmil-images/mine/6cg0) | Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | Authors: | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | Deposit date: | 2018-02-19 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
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1S0M
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![BU of 1s0m by Molmil](/molmil-images/mine/1s0m) | Crystal structure of a Benzo[a]pyrene Diol Epoxide adduct in a ternary complex with a DNA polymerase | Descriptor: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', ... | Authors: | Ling, H, Sayer, J.M, Boudsocq, F, Plosky, B.S, Woodgate, R, Yang, W. | Deposit date: | 2003-12-31 | Release date: | 2004-03-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proc.Natl.Acad.Sci.USA, 101, 2004
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1RYS
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![BU of 1rys by Molmil](/molmil-images/mine/1rys) | REPLICATION OF A CIS-SYN THYMINE DIMER AT ATOMIC RESOLUTION | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*A)-3', 5'-D(*TP*CP*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | Authors: | Ling, H, Boudsocq, F, Plosky, B, Woodgate, R, Yang, W. | Deposit date: | 2003-12-22 | Release date: | 2004-02-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Replication of a Cis-Syn Thymine Dimer at Atomic Resolution Nature, 424, 2003
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1RYR
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![BU of 1ryr by Molmil](/molmil-images/mine/1ryr) | REPLICATION OF A CIS-SYN THYMINE DIMER AT ATOMIC RESOLUTION | Descriptor: | 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', 5'-D(*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Ling, H, Boudsocq, F, Plosky, B, Woodgate, R, Yang, W. | Deposit date: | 2003-12-22 | Release date: | 2004-02-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Replication of a Cis-Syn Thymine Dimer at Atomic Resolution Nature, 424, 2003
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1S10
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![BU of 1s10 by Molmil](/molmil-images/mine/1s10) | Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', 5'-D(*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | Authors: | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | Deposit date: | 2004-01-05 | Release date: | 2004-03-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts. Mol.Cell, 13, 2004
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