7M7N
 
 | | Human DNA Pol eta with 2'-FA-ended primer and dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(AF5))-3'), DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7T
 | | Human DNA Pol eta S113A with dT-ended primer and dATP: in crystallo reaction for 0 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M85
 | | Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 80 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7Y
 | | Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 0 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M8B
 | | Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 140 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M88
 | | Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 300 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M8D
 | | Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 300 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7S
 | | Human DNA Pol eta S113A with dT-ended primer and 0.1 mM dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M89
 | | Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 0 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7M
 | | Human DNA Pol eta with rA-ended primer and dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7L
 | | Human DNA Pol eta with dA-ended primer and dAMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7U
 | | Human DNA Pol eta S113A with dT-ended primer and dATP: in crystallo reaction for 480s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7Z
 | | Human DNA Pol eta with dA-ended primer and dATP: in crystallo reaction for 40 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M8A
 | | Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 40 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M83
 | | Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 0 s | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), ... | | 著者 | Gregory, M.T, Gao, Y, Yang, W. | | 登録日 | 2021-03-29 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4CVH
 | | Crystal structure of human isoprenoid synthase domain-containing protein | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ISOPRENOID SYNTHASE DOMAIN-CONTAINING PROTEIN, ... | | 著者 | Kopec, J, Froese, D.S, Krojer, T, Newman, J, Kiyani, W, Goubin, S, Strain-Damerell, C, Vollmar, M, von Delft, F, Burgess-Brown, N, Arrowsmith, C, Edwards, A, Bountra, C, Lefeber, D.J, Yue, W.W. | | 登録日 | 2014-03-27 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Human Ispd is a Cytidyltransferase Required for Dystroglycan O-Mannosylation.
Chem.Biol., 22, 2015
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3LWO
 | | Structure of H/ACA RNP bound to a substrate RNA containing 5BrU | | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(5BU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | 登録日 | 2010-02-24 | | 公開日 | 2010-07-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.855 Å) | | 主引用文献 | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
J.Mol.Biol., 401, 2010
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3LWP
 | | Structure of H/ACA RNP bound to a substrate RNA containing 5BrdU | | 分子名称: | 5'-R(*GP*AP*GP*CP*GP*(BRU)P*GP*CP*GP*GP*UP*UP*U)-3, 50S ribosomal protein L7Ae, H/ACA RNA, ... | | 著者 | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | 登録日 | 2010-02-24 | | 公開日 | 2010-07-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
J.Mol.Biol., 401, 2010
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8EBU
 | | XPC release from Core7-XPA-DNA (Cy5) | | 分子名称: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | | 著者 | Kim, J, Yang, W. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8EBS
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8EBT
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8EBY
 | | XPC release from Core7-XPA-DNA (AP) | | 分子名称: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | | 著者 | Kim, J, Yang, W. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8EBV
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8EBW
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8EBX
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