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PDB: 17 件
1J3H
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Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, cAMP-dependent protein kinase, alpha-catalytic subunit
著者Akamine, P, Madhusudan, Wu, J, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S.
登録日2003-01-31
公開日2003-03-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dynamic Features of cAMP-dependent Protein Kinase Revealed by Apoenzyme Crystal Structure
J.Mol.Biol., 327, 2003
1JBP
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Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Substrate Peptide, ADP and Detergent
分子名称: ADENOSINE-5'-DIPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN FORM, ...
著者Madhusudan, Trafny, E.A, Xuong, N.H, Adams, J.A, Ten Eyck, L.F, Taylor, S.S, Sowadski, J.M.
登録日2001-06-06
公開日2001-06-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer.
Protein Sci., 3, 1994
1RDQ
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Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Yang, J, Ten Eyck, L.F, Xuong, N.H, Taylor, S.S.
登録日2003-11-05
公開日2004-04-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism.
J.Mol.Biol., 336, 2004
1NAT
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CRYSTAL STRUCTURE OF SPOOF FROM BACILLUS SUBTILIS
分子名称: SPORULATION RESPONSE REGULATORY PROTEIN
著者Madhusudan, Zapf, J, Hoch, J.A, Whiteley, J.M, Xuong, N.H, Varughese, K.I.
登録日1997-09-09
公開日1998-10-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A response regulatory protein with the site of phosphorylation blocked by an arginine interaction: crystal structure of Spo0F from Bacillus subtilis.
Biochemistry, 36, 1997
1CTP
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STRUCTURE OF THE MAMMALIAN CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND AN INHIBITOR PEPTIDE DISPLAYS AN OPEN CONFORMATION
分子名称: MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE, cAMP-dependent protein kinase inhibitor, ...
著者Karlsson, R, Zheng, J, Xuong, N.H, Taylor, S.S, Sowadski, J.M.
登録日1993-04-08
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the mammalian catalytic subunit of cAMP-dependent protein kinase and an inhibitor peptide displays an open conformation.
Acta Crystallogr.,Sect.D, 49, 1993
1REK
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Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 8
分子名称: 3-[(3-SEC-BUTYL-4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXY-5-METHOXYBENZOYL)BENZOATE, PENTANAL, cAMP-dependent protein kinase, ...
著者Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S.
登録日2003-11-06
公開日2004-02-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit
Biochemistry, 43, 2004
1REJ
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Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 1
分子名称: 3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-HYDROXYBENZOATE, cAMP-dependent protein kinase, alpha-catalytic subunit
著者Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S.
登録日2003-11-06
公開日2004-02-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit
Biochemistry, 43, 2004
1RE8
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Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 2
分子名称: 3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXYBENZOYL)BENZOATE, N-OCTANE, cAMP-dependent protein kinase, ...
著者Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S.
登録日2003-11-06
公開日2004-02-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit
Biochemistry, 43, 2004
1NE6
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Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, cAMP-dependent protein kinase type I-alpha regulatory chain
著者Wu, J, Jones, J.M, Xuong, N.H, Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1NE4
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Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, cAMP-dependent protein kinase type I-alpha regulatory chain
著者Wu, J, Jones, J.M, Xuong, N.H, Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1CX4
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CRYSTAL STRUCTURE OF A DELETION MUTANT OF THE TYPE II BETA REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT TYPE II BETA
著者Diller, T.C, Xuong, N.H, Taylor, S.S.
登録日1999-08-28
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit.
Structure, 9, 2001
1SYK
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Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation
分子名称: cAMP-dependent protein kinase, alpha-catalytic subunit
著者Wu, J, Yang, J, Madhusudan, N, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S.
登録日2004-04-01
公開日2005-05-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.
Protein Sci., 14, 2005
1SRR
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CRYSTAL STRUCTURE OF A PHOSPHATASE RESISTANT MUTANT OF SPORULATION RESPONSE REGULATOR SPO0F FROM BACILLUS SUBTILIS
分子名称: CALCIUM ION, SPORULATION RESPONSE REGULATORY PROTEIN
著者Madhusudan, Whiteley, J.M, Hoch, J.A, Zapf, J, Xuong, N.H, Varughese, K.I.
登録日1996-04-10
公開日1997-04-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis.
Structure, 4, 1996
1HDR
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THE CRYSTALLOGRAPHIC STRUCTURE OF A HUMAN DIHYDROPTERIDINE REDUCTASE NADH BINARY COMPLEX EXPRESSED IN ESCHERICHIA COLI BY A CDNA CONSTRUCTED FROM ITS RAT HOMOLOGUE
分子名称: DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Varughese, K.I, Su, Y, Xuong, N.H, Whiteley, J.M.
登録日1993-08-18
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystallographic structure of a human dihydropteridine reductase NADH binary complex expressed in Escherichia coli by a cDNA constructed from its rat homologue.
J.Biol.Chem., 268, 1993
1DIR
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CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER
分子名称: DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Varughese, K.I, Su, Y, Skinner, M.M, Matthews, D.A, Whitely, J.M, Xuong, N.H.
登録日1994-04-18
公開日1994-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver.
Acta Crystallogr.,Sect.D, 50, 1994
1CHG
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CHYMOTRYPSINOGEN,2.5 ANGSTROMS CRYSTAL STRUCTURE, COMPARISON WITH ALPHA-CHYMOTRYPSIN,AND IMPLICATIONS FOR ZYMOGEN ACTIVATION
分子名称: CHYMOTRYPSINOGEN A
著者Freer, S.T, Kraut, J, Robertus, J.D, Wright, H.T, Xuong, N.H.
登録日1975-03-01
公開日1976-11-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Chymotrypsinogen: 2.5-angstrom crystal structure, comparison with alpha-chymotrypsin, and implications for zymogen activation.
Biochemistry, 9, 1970
1DHR
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CRYSTAL STRUCTURE OF RAT LIVER DIHYDROPTERIDINE REDUCTASE
分子名称: DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Varughese, K.I, Skinner, M.M, Whiteley, J.M, Matthews, D.A, Xuong, N.H.
登録日1992-03-30
公開日1993-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of rat liver dihydropteridine reductase.
Proc.Natl.Acad.Sci.USA, 89, 1992

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