8WAN
 
 | | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-07 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.07 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAS
 | | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.13 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAY
 | | De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAP
 | | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (5.85 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAR
 | | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAQ
 | | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.29 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAZ
 | | De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WB0
 | | De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAT
 | | De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAX
 | | De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAW
 | | De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAU
 | | De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
8WAV
 | | De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt downstream of TSS | | 分子名称: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
|
|
6HN5
 | | Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | | 登録日 | 2018-09-14 | | 公開日 | 2018-11-21 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
|
|
6HN4
 | | Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4 | | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | | 登録日 | 2018-09-14 | | 公開日 | 2018-11-21 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
|
|
6IMB
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... | | 著者 | Zhang, X, Su, H, Xu, Y. | | 登録日 | 2018-10-22 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.549 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
|
|
6IMI
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 6-ethoxy-7-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... | | 著者 | Zhang, X, Su, H, Xu, Y. | | 登録日 | 2018-10-23 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
|
|
6IMD
 | | Crystal structure of PDE4D complexed with a novel inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ... | | 著者 | Zhang, X, Su, H, Xu, Y. | | 登録日 | 2018-10-22 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
|
|
8JWZ
 | | Crystal structure of A2AR-T4L in complex with AB928 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]-1,2,3-triazol-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ... | | 著者 | Weng, Y, Chen, Y, Xu, Y, Song, G. | | 登録日 | 2023-06-29 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.
Sci China Life Sci, 67, 2024
|
|
8JWY
 | | Crystal structure of A2AR-T4L in complex with 2-118 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[2-oxidanylidene-1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]pyridin-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ... | | 著者 | Weng, Y, Chen, Y, Xu, Y, Song, G. | | 登録日 | 2023-06-29 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.
Sci China Life Sci, 67, 2024
|
|
2D5L
 | | Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis | | 分子名称: | SULFATE ION, dipeptidyl aminopeptidase IV, putative | | 著者 | Nakajima, Y, Ito, K, Xu, Y, Yamada, N, Onohara, Y, Yoshimoto, T. | | 登録日 | 2005-11-02 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
J.Mol.Biol., 362, 2006
|
|
2DCM
 | | The Crystal Structure of S603A Mutated Prolyl Tripeptidyl Aminopeptidase Complexed with Substrate | | 分子名称: | GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE, dipeptidyl aminopeptidase IV, putative | | 著者 | Nakajima, Y, Ito, K, Xu, Y, Yamada, N, Onohara, Y, Yoshimoto, T. | | 登録日 | 2006-01-09 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
J.Mol.Biol., 362, 2006
|
|
3N9M
 | | ceKDM7A from C.elegans, alone | | 分子名称: | FE (II) ION, Putative uncharacterized protein, ZINC ION | | 著者 | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | | 登録日 | 2010-05-31 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | | 主引用文献 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
|
|
3N9P
 | | ceKDM7A from C.elegans, complex with H3K4me3K27me2 peptide and NOG | | 分子名称: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | | 著者 | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | | 登録日 | 2010-05-31 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | | 主引用文献 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
|
|
3N9O
 | | ceKDM7A from C.elegans, complex with H3K4me3 peptide, H3K9me2 peptide and NOG | | 分子名称: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | | 著者 | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | | 登録日 | 2010-05-31 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.309 Å) | | 主引用文献 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
|
|
