5W9Q
 
 | | Zinc finger region of MBD1 in complex with CpG DNA | | Descriptor: | Methyl-CpG-binding domain protein 1, UNKNOWN ATOM OR ION, ZINC ION, ... | | Authors: | Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-23 | | Release date: | 2017-10-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
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5W9S
 | | Zinc finger of human CXXC5 in complex with CpG DNA | | Descriptor: | CXXC-type zinc finger protein 5, CpG DNA fragment, SULFATE ION, ... | | Authors: | Liu, K, Xu, C, Tempel, W, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-23 | | Release date: | 2017-10-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
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4O64
 | | Zinc fingers of KDM2B | | Descriptor: | Lysine-specific demethylase 2B, UNKNOWN ATOM OR ION, ZINC ION | | Authors: | Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-20 | | Release date: | 2014-04-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
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2LLL
 | | Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A | | Descriptor: | Lamin-B2 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Xu, C, Min, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | | Deposit date: | 2011-11-11 | | Release date: | 2011-12-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of c-terminal globular domain of human Lamin-B2
To be Published
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4RCJ
 | | Crystal structure of YTHDF1 YTH domain in complex with 5mer m6A RNA | | Descriptor: | RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing family protein 1 | | Authors: | Tempel, W, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-09-16 | | Release date: | 2014-11-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
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4RCM
 | | Crystal structure of the Pho92 YTH domain in complex with m6A | | Descriptor: | Methylated RNA-binding protein 1, RNA (5'-R(*UP*G)-D(*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION | | Authors: | Tempel, W, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-09-16 | | Release date: | 2014-11-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
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6C2F
 | | MBD2 in complex with methylated DNA | | Descriptor: | 12-mer DNA, Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION | | Authors: | Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-01-08 | | Release date: | 2018-02-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | MBD2 in complex with methylated DNA
to be published
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6ICT
 | | Structure of SETD3 bound to SAH and methylated actin | | Descriptor: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | | Authors: | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-09-07 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.952 Å) | | Cite: | Structural insights into SETD3-mediated histidine methylation on beta-actin.
Elife, 8, 2019
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6ICV
 | | Structure of SETD3 bound to SAH and unmodified actin | | Descriptor: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | | Authors: | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-09-07 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural insights into SETD3-mediated histidine methylation on beta-actin.
Elife, 8, 2019
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6J8O
 | | Structure of a hypothetical protease | | Descriptor: | 8-mer peptide, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C. | | Deposit date: | 2019-01-20 | | Release date: | 2020-01-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.855 Å) | | Cite: | Structure of a hypothetical protease
To Be Published
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6J8F
 | | Crystal structure of SVBP-VASH1 with peptide mimic the C-terminal of alpha-tubulin | | Descriptor: | 8-mer peptide, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-01-18 | | Release date: | 2019-06-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.283 Å) | | Cite: | Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
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6J9H
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6J8N
 | | Crystal structure of SVBP-VASH1 complex, mutation C169A of VASH1 | | Descriptor: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-01-20 | | Release date: | 2019-06-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
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6J91
 | | Structure of a hypothetical protease | | Descriptor: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | Authors: | Liao, S, Gao, J, Xu, C. | | Deposit date: | 2019-01-21 | | Release date: | 2019-06-19 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
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6K7V
 | | Structure of NLRP1 CARD filament | | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | | Authors: | Gong, Q, Xu, C, Zhang, J, Wu, B. | | Deposit date: | 2019-06-09 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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6K9F
 | | Structure of unknow protein 4 | | Descriptor: | Caspase recruitment domain-containing protein 8 | | Authors: | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | | Deposit date: | 2019-06-15 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8.
Nat Commun, 12, 2021
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3PD7
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7CHJ
 | | crystal structure of pco4 | | Descriptor: | CITRIC ACID, FE (III) ION, Plant cysteine oxidase 4 | | Authors: | Guo, Q, Xu, C, Liao, S. | | Deposit date: | 2020-07-05 | | Release date: | 2020-11-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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3R93
 | | Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide | | Descriptor: | H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION | | Authors: | Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2011-03-24 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.057 Å) | | Cite: | Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
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7CNG
 | | Structure of CDK5R1 bound FEM1B | | Descriptor: | Protein fem-1 homolog B,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION | | Authors: | Chen, X, Liao, S, Xu, C. | | Deposit date: | 2020-07-31 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.49 Å) | | Cite: | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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5UMV
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7CHI
 | | crystal structure of pco5 | | Descriptor: | FE (III) ION, Plant cysteine oxidase 5 | | Authors: | Guo, Q, Xu, C, Liao, S. | | Deposit date: | 2020-07-05 | | Release date: | 2020-11-25 | | Last modified: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana.
J.Struct.Biol., 213, 2021
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3EOP
 | | Crystal Structure of the DUF55 domain of human thymocyte nuclear protein 1 | | Descriptor: | SULFATE ION, Thymocyte nuclear protein 1 | | Authors: | Yu, F, Song, A, Xu, C, Sun, L, Li, L, Tang, L, Hu, H, He, J. | | Deposit date: | 2008-09-29 | | Release date: | 2009-09-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Determining the DUF55-domain structure of human thymocyte nuclear protein 1 from crystals partially twinned by tetartohedry
Acta Crystallogr.,Sect.D, 65, 2009
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1YOP
 | | The solution structure of Kti11p | | Descriptor: | Kti11p, ZINC ION | | Authors: | Sun, J, Zhang, J, Wu, F, Xu, C, Li, S, Zhao, W, Wu, Z, Wu, J, Zhou, C.-Z, Shi, Y. | | Deposit date: | 2005-01-28 | | Release date: | 2005-04-05 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Biochemistry, 44, 2005
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6ASD
 | | Zinc finger region of human TET1 in complex with CpG DNA | | Descriptor: | DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase TET1, UNKNOWN ATOM OR ION, ... | | Authors: | Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-08-24 | | Release date: | 2017-10-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
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