3CSF
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3Q4C
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![BU of 3q4c by Molmil](/molmil-images/mine/3q4c) | Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292 | Descriptor: | Serine/threonine-protein kinase B-raf, [(1,2,3,4,5,6-eta)-(1S,2R,3R,4R,5S,6S)-1-carboxycyclohexane-1,2,3,4,5,6-hexayl](chloro)(3-methyl-5,7-dioxo-6,7-dihydro-5H-pyrido[2,3-a]pyrrolo[3,4-c]carbazol-12-ide-kappa~2~N~1~,N~12~)ruthenium(1+) | Authors: | Xie, P, Streu, C, Qin, J, Pregman, H, Pagano, N, Meggers, E, Marmorstein, R. | Deposit date: | 2010-12-23 | Release date: | 2011-03-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry, 48, 2009
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3CST
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3KVQ
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1ZMS
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![BU of 1zms by Molmil](/molmil-images/mine/1zms) | LMP1 Protein binds to TRAF3 as a structural CD40 | Descriptor: | Latent membrane protein 1, TNF receptor associated factor 3 | Authors: | Wu, S.D, Xie, P, Welsh, K, Li, C, Ni, C.-Z, Zhu, X, Reed, J.C, Satterthwait, A.C, Bishop, G.A, Ely, K.R. | Deposit date: | 2005-05-10 | Release date: | 2005-07-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | LMP1 protein from the Epstein Barr virus is a structural CD40 decoy in B lymphocytes fro binding to TRAF3 J.Biol.Chem., 39, 2005
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1AGN
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![BU of 1agn by Molmil](/molmil-images/mine/1agn) | X-RAY STRUCTURE OF HUMAN SIGMA ALCOHOL DEHYDROGENASE | Descriptor: | ACETATE ION, HUMAN SIGMA ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Hurley, T.D, Xie, P. | Deposit date: | 1996-06-04 | Release date: | 1997-03-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity. J.Biol.Chem., 272, 1997
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4E26
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![BU of 4e26 by Molmil](/molmil-images/mine/4e26) | BRAF in complex with an organic inhibitor 7898734 | Descriptor: | 5-chloro-7-[(R)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol, Serine/threonine-protein kinase B-raf | Authors: | Qin, J, Xie, P, Ventocilla, C, Zhou, G, Vultur, A, Chen, Q, Herlyn, M, Winkler, J, Marmorstein, R. | Deposit date: | 2012-03-07 | Release date: | 2012-05-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Identification of a Novel Family of BRAF(V600E) Inhibitors. J.Med.Chem., 55, 2012
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