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PDB: 12 件

6WCD
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Crystal Structure of Xenopus laevis APE2 Catalytic Domain
分子名称: 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Wojtaszek, J.L, Wallace, B.D, Williams, R.S.
登録日2020-03-30
公開日2020-05-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease.
Mol.Cell, 78, 2020
4FJO
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Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex
分子名称: DNA polymerase kappa, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
著者Wojtaszek, J, Lee, C.-J, Zhou, P.
登録日2012-06-11
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.718 Å)
主引用文献Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric Pol zeta and Pol kappa
J.Biol.Chem., 287, 2012
8F6B
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Crystal structure of murine PolG2 hexamer bound to DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*GP*GP*TP*AP*GP*GP*CP*GP*CP*CP*TP*AP*CP*CP*AP*G)-3'), ...
著者Wojtaszek, J.L, Hoff, K.E, Williams, R.S.
登録日2022-11-16
公開日2023-08-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.
Nucleic Acids Res., 51, 2023
6C59
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Chimeric Pol kappa RIR Rev1 C-terminal domain
分子名称: ACETATE ION, Chimeric Pol kappa RIR Rev1 C-terminal domain
著者Wojtaszek, J.L, Zhou, P.
登録日2018-01-15
公開日2019-06-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
Cell, 178, 2019
7N3Z
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Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA-(apurinic or apyrimidinic site) endonuclease 2, ...
著者Wojtaszek, J.L, Wallace, B.D, Williams, R.S.
登録日2021-06-02
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Cell Rep, 41, 2022
7N3Y
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Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain E59Q/D222N Mutant in Complex with DNA
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ...
著者Wojtaszek, J.L, Krahn, J, Wallace, B.D, Williams, R.S.
登録日2021-06-02
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Cell Rep, 41, 2022
8F69
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Crystal structure of murine PolG2 dimer bound to DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Wojtaszek, J.L, Hoff, K.E, Williams, R.S.
登録日2022-11-16
公開日2023-08-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.
Nucleic Acids Res., 51, 2023
2MUQ
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Solution Structure of the Human FAAP20 UBZ
分子名称: Fanconi anemia-associated protein of 20 kDa, ZINC ION
著者Wojtaszek, J.L, Wang, S, Zhou, P.
登録日2014-09-16
公開日2014-12-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.
Nucleic Acids Res., 42, 2014
7JL5
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Crystal structure of human NEIL3 tandem zinc finger GRF domains
分子名称: Endonuclease 8-like 3, ZINC ION
著者Rodriguez, A.A, Wojtaszek, J.L, Williams, R.S, Eichman, B.F.
登録日2020-07-29
公開日2020-09-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An autoinhibitory role for the GRF zinc finger domain of DNA glycosylase NEIL3.
J.Biol.Chem., 295, 2020
2LSJ
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BU of 2lsj by Molmil
Solution structure of the mouse Rev1 CTD in complex with the Rev1-interacting Region (RIR)of Pol Kappa
分子名称: DNA polymerase kappa, DNA repair protein REV1
著者Liu, J, Wojtaszek, J, Zhou, P.
登録日2012-05-01
公開日2012-06-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa.
J.Biol.Chem., 287, 2012
2LSG
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Solution structure of the mouse Rev1 C-terminal domain
分子名称: DNA repair protein REV1
著者Liu, J, Wojtaszek, J, Zhou, P.
登録日2012-04-30
公開日2012-06-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa.
J.Biol.Chem., 287, 2012
2MUR
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BU of 2mur by Molmil
Solution Structure of the Human FAAP20 UBZ-Ubiquitin Complex
分子名称: Fanconi anemia-associated protein of 20 kDa, Ubiquitin, ZINC ION
著者Wang, S, Wojtaszek, J.L, Zhou, P.
登録日2014-09-16
公開日2014-12-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.
Nucleic Acids Res., 42, 2014

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件を2024-10-30に公開中

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