1GVY
 
 | | Substrate distorsion by beta-mannanase from Pseudomonas cellulosa | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DINITROPHENYLENE, MANNAN ENDO-1,4-BETA-MANNOSIDASE, ... | | 著者 | Ducros, V, Zechel, D.L, Gilbert, H.J, Szabo, L, Withers, S.G, Davies, G.J. | | 登録日 | 2002-02-28 | | 公開日 | 2002-09-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Substrate Distortion by a Beta-Mannanase: Snapshots of the Michaelis and Covalent-Intermediate Complexes Suggest a B2,5 Conformation for the Transition State
Angew.Chem.Int.Ed.Engl., 41, 2002
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1H6M
 | | Covalent glycosyl-enzyme intermediate of hen egg white lysozyme | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose, LYSOZYME C, SODIUM ION | | 著者 | Vocadlo, D.J, Davies, G.J, Laine, R, Withers, S.G. | | 登録日 | 2001-06-19 | | 公開日 | 2001-08-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Catalysis by Hen Egg-White Lysozyme Proceeds Via a Covalent Intermediate
Nature, 412, 2001
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1GW1
 | | Substrate distortion by beta-mannanase from Pseudomonas cellulosa | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DINITROPHENYLENE, MANNAN ENDO-1,4-BETA-MANNOSIDASE, ... | | 著者 | Ducros, V, Zechel, D.L, Gilbert, H.J, Szabo, L, Withers, S.G, Davies, G.J. | | 登録日 | 2002-03-01 | | 公開日 | 2002-09-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Substrate Distortion by a Beta-Mannanase: Snapshots of the Michaelis and Covalent-Intermediate Complexes Suggest a B2,5 Conformation for the Transition State
Angew.Chem.Int.Ed.Engl., 41, 2002
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3SCU
 | | Crystal Structure of Rice BGlu1 E386G Mutant Complexed with Cellopentaose | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCO
 | | Crystal Structure of Rice BGlu1 E386G Mutant Complexed with alpha-Glucosyl Fluoride | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, GLYCEROL, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCV
 | | Crystal Structure of Rice BGlu1 E386G/S334A Mutant Complexed with Cellotetraose | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCQ
 | | Crystal Structure of Rice BGlu1 E386A Mutant Complexed with alpha-Glucosyl Fluoride | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCW
 | | Crystal Structure of Rice BGlu1 E386G/Y341A Mutant Complexed with Cellotetraose | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCP
 | | Crystal Structure of Rice BGlu1 E386A Mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, GLYCEROL, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCS
 | | Crystal Structure of Rice BGlu1 E386S Mutant Complexed with alpha-Glucosyl Fluoride | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, GLYCEROL, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCN
 | | Crystal Structure of Rice BGlu1 E386G Mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCT
 | | Crystal Structure of Rice BGlu1 E386G Mutant Complexed with Cellotetraose | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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3SCR
 | | Crystal Structure of Rice BGlu1 E386S Mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, GLYCEROL, ... | | 著者 | Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. | | 登録日 | 2011-06-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
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1HV1
 | | DISSECTING ELECTROSTATIC INTERACTIONS AND THE PH-DEPENDENT ACTIVITY OF A FAMILY 11 GLYCOSIDASE | | 分子名称: | ENDO-1,4-BETA-XYLANASE | | 著者 | Joshi, M.D, Sidhu, G, Nielsen, J.E, Brayer, G.D, Withers, S.G, McIntosh, L.P. | | 登録日 | 2001-01-05 | | 公開日 | 2001-09-14 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase.
Biochemistry, 40, 2001
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1J01
 | | Crystal Structure Of The Xylanase Cex With Xylobiose-Derived Inhibitor Isofagomine lactam | | 分子名称: | (3S,4R)-3-hydroxy-2-oxopiperidin-4-yl beta-D-xylopyranoside, beta-1,4-xylanase | | 著者 | Williams, S.J, Notenboom, V, Wicki, J, Rose, D.R, Withers, S.G. | | 登録日 | 2002-10-25 | | 公開日 | 2002-11-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A New, Simple, High-Affinity Glycosidase Inhibitor: Analysis of Binding through X-ray Crystallography, Mutagenesis, and Kinetic Analysis
J.Am.Chem.Soc., 122, 2000
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1KBK
 | | Mechanistic Analyses of Catalysis in Human Pancreatic Alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | | 著者 | Rydberg, E.H, Li, C, Maurus, R, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-06 | | 公開日 | 2002-04-10 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids.
Biochemistry, 41, 2002
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1KBB
 | | Mechanistic Analyses of Catalysis in Human Pancreatic alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids | | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION, ... | | 著者 | Rydberg, E.H, Li, C, Maurus, R, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-05 | | 公開日 | 2002-04-10 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids.
Biochemistry, 41, 2002
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1JZ2
 | | E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE (ORTHORHOMBIC) | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-2-fluoro-beta-D-galactopyranose, Beta-Galactosidase, ... | | 著者 | Juers, D.H, McCarter, J.D, Mackenzie, L, Withers, S.G, Matthews, B.W. | | 登録日 | 2001-09-13 | | 公開日 | 2001-12-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase
Biochemistry, 40, 2001
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1KB3
 | | Three Dimensional Structure Analysis of the R195A Variant of Human Pancreatic Alpha Amylase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-05 | | 公開日 | 2002-05-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
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1KGU
 | | THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337A VARIANT OF HUMAN PANCREATIC ALPHA-AMYLASE | | 分子名称: | ALPHA-AMYLASE, PANCREATIC, CALCIUM ION | | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-28 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
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1KGX
 | | Three Dimensional Structure Analysis of the R195Q Variant of Human Pancreatic Alpha Amylase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-28 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
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1KGW
 | | THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337Q VARIANT OF HUMAN PANCREATIC ALPHA-MYLASE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2001-11-28 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
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1M04
 | | Mutant Streptomyces plicatus beta-hexosaminidase (D313N) in complex with product (GlcNAc) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ... | | 著者 | Williams, S.J, Mark, B.L, Vocadlo, D.J, James, M.N.G, Withers, S.G. | | 登録日 | 2002-06-11 | | 公開日 | 2002-12-11 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical
role in substrate-assisted catalysis by orienting the 2-acetamido group
and stabilizing the transition state.
J.Biol.Chem., 277, 2002
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2WAR
 | | Hen Egg White Lysozyme E35Q chitopentaose complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LYSOZYME C | | 著者 | Davies, G.J, Withers, S.G, Vocadlo, D.J. | | 登録日 | 2009-02-13 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Chitopentaose Complex of a Mutant Hen Egg-White Lysozyme Displays No Distortion of the -1 Sugar Away from a 4C1 Chair Conformation
Aust.J.Chem., 62, 2009
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2WBK
 | | Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis | | 分子名称: | 1,2-ETHANEDIOL, 2,4-dinitrophenyl 2-deoxy-2-fluoro-beta-D-mannopyranoside, BETA-MANNOSIDASE, ... | | 著者 | Offen, W.A, Zechel, D.L, Withers, S.G, Gilbert, H.J, Davies, G.J. | | 登録日 | 2009-03-02 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the Michaelis Complex of Beta-Mannosidase, Man2A, Provides Insight Into the Conformational Itinerary of Mannoside Hydrolysis.
Cell(Cambridge,Mass.), 18, 2009
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