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PDB: 80 件
1FUY
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CRYSTAL STRUCTURE OF BETAA169L/BETAC170W DOUBLE MUTANT OF TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUORO-INDOLE-PROPANOL PHOSPHATE
分子名称: 5-FLUOROINDOLE PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Weyand, M, Schlichting, I.
登録日2000-09-18
公開日2001-01-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for the impaired channeling and allosteric inter-subunit communication in the beta A169L/beta C170W mutant of tryptophan synthase.
J.Biol.Chem., 275, 2000
7NXZ
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Synthetic glycoform of Human Interleukin 6
分子名称: Interleukin-6
著者Weyand, M, Unverzagt, C.
登録日2021-03-19
公開日2021-04-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance.
Angew.Chem.Int.Ed.Engl., 60, 2021
1QI9
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BU of 1qi9 by Molmil
X-RAY SIRAS STRUCTURE DETERMINATION OF A VANADIUM-DEPENDENT HALOPEROXIDASE FROM ASCOPHYLLUM NODOSUM AT 2.0 A RESOLUTION
分子名称: VANADATE ION, Vanadium-dependent bromoperoxidase
著者Weyand, M, Hecht, H.-J, Kiess, M, Liaud, M.F, Vilter, H, Schomburg, D.
登録日1999-06-10
公開日2000-06-10
最終更新日2023-06-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution.
J.Mol.Biol., 293, 1999
1QOQ
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BU of 1qoq by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH INDOLE GLYCEROL PHOSPHATE
分子名称: INDOLE-3-GLYCEROL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
著者Weyand, M, Schlichting, I.
登録日1999-11-15
公開日2000-11-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Wild-Type Tryptophan Synthase Complexed with the Natural Substrate Indole-3-Glycerol Phosphate.
Biochemistry, 38, 1999
8ANC
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BU of 8anc by Molmil
14-3-3 sigma sirtuin-3 phospho-peptide complex
分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
著者Weyand, M, Steegborn, C, Debbert, L.
登録日2022-08-05
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献14-3-3 sigma sirtuin-3 phospho-peptide complex
To Be Published
8ANB
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BU of 8anb by Molmil
14-3-3 sigma sirtuin-1 phospho-peptide complex
分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
著者Weyand, M, Steegborn, C, Debbert, L.
登録日2022-08-05
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献14-3-3 sigma sirtuin-1 phospho-peptide complex
To Be Published
3UAL
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BU of 3ual by Molmil
Crystal Structure of 14-3-3 epsilon with Mlf1 peptide
分子名称: 14-3-3 protein epsilon, Myeloid leukemia factor 1, TERTIARY-BUTYL ALCOHOL
著者Weyand, M, Ottmann, C.
登録日2011-10-21
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights of the MLF1/14-3-3 interaction.
Febs J., 279, 2012
1QOP
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BU of 1qop by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH INDOLE PROPANOL PHOSPHATE
分子名称: INDOLE-3-PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Weyand, M, Schlichting, I.
登録日1999-11-15
公開日2000-11-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of Wild-Type Tryptophan Synthase Complexed with the Natural Substrate Indole-3-Glycerol Phosphate
Biochemistry, 38, 1999
4BGC
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BU of 4bgc by Molmil
T1 domain of the renal potassium channel Kv1.3
分子名称: POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3
著者Weyand, M, Kremer, W, Kalbitzer, H.R.
登録日2013-03-25
公開日2013-10-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献1.2 A X-Ray Structure of the Renal Potassium Channel Kv1.3 T1 Domain.
Protein J., 32, 2013
1K8Y
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CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH D,L-ALPHA-GLYCEROL-3-PHOSPHATE
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
登録日2001-10-26
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
J.Biol.Chem., 277, 2002
4BUZ
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BU of 4buz by Molmil
SIR2 COMPLEX STRUCTURE MIXTURE OF EX-527 INHIBITOR AND REACTION PRODUCTS OR OF REACTION SUBSTRATES P53 PEPTIDE AND NAD
分子名称: (1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide, 1,2-ETHANEDIOL, 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, ...
著者Weyand, M, Lakshminarasimhan, M, Gertz, M, Steegborn, C.
登録日2013-06-24
公開日2013-07-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ex-527 Inhibits Sirtuins by Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism
Proc.Natl.Acad.Sci.USA, 110, 2013
1K7E
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BU of 1k7e by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
分子名称: N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
登録日2001-10-19
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.
J.Biol.Chem., 277, 2002
1K8Z
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BU of 1k8z by Molmil
CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
分子名称: N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
登録日2001-10-26
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
J.Biol.Chem., 277, 2002
1K7X
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BU of 1k7x by Molmil
CRYSTAL STRUCTURE OF THE BETA-SER178PRO MUTANT OF TRYPTOPHAN SYNTHASE
分子名称: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
著者Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
登録日2001-10-22
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
J.Biol.Chem., 277, 2002
1K7F
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BU of 1k7f by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]VALINE ACID
分子名称: N-[1H-INDOL-3-YL-ACETYL]VALINE ACID, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
著者Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
登録日2001-10-19
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.
J.Biol.Chem., 277, 2002
1K3U
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BU of 1k3u by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]ASPARTIC ACID
分子名称: N-[1H-INDOL-3-YL-ACETYL]ASPARTIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
登録日2001-10-04
公開日2002-07-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.
J.Biol.Chem., 277, 2002
3CU8
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BU of 3cu8 by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
分子名称: 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ...
著者Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C.
登録日2008-04-16
公開日2009-05-05
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol. Cell. Biol., 30, 2010
3LW1
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BU of 3lw1 by Molmil
Binary complex of 14-3-3 sigma and p53 pT387-peptide
分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ...
著者Schumacher, B, Mondry, J, Thiel, P, Weyand, M, Ottmann, C.
登録日2010-02-23
公開日2010-03-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer
Febs Lett., 584, 2010
1Z2C
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BU of 1z2c by Molmil
Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
分子名称: Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A.
登録日2005-03-08
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
3NKX
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BU of 3nkx by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
分子名称: 14-3-3 protein zeta/delta, PROPANOIC ACID, Peptide of RAF proto-oncogene serine/threonine-protein kinase
著者Schumacher, B, Weyand, M, Ottmann, C.
登録日2010-06-21
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
Mol.Cell.Biol., 30, 2010
3IQU
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BU of 3iqu by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer)
分子名称: 14-3-3 protein sigma, 6-mer from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-21
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQJ
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BU of 3iqj by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (10mer)
分子名称: 10-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-20
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQV
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BU of 3iqv by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer) and stabilisator Fusicoccin
分子名称: 14-3-3 protein sigma, 6-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
著者Ottmann, C, Weyand, M.
登録日2009-08-21
公開日2010-09-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
2WBL
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BU of 2wbl by Molmil
Three-dimensional structure of a binary ROP-PRONE complex
分子名称: RAC-LIKE GTP-BINDING PROTEIN ARAC2, RHO OF PLANTS GUANINE NUCLEOTIDE EXCHANGE FACTOR 8
著者Thomas, C, Fricke, I, Weyand, M, Berken, A.
登録日2009-03-02
公開日2009-04-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献3D Structure of a Binary Rop-Prone Complex: The Final Intermediate for a Complete Set of Molecular Snapshots of the Ropgef Reaction.
Biol.Chem., 390, 2009
7OBZ
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Structure of RsLOV D109G
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, LOV protein, ...
著者Moeglich, A, Krafft, T.G.A, Weyand, M.
登録日2021-04-25
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Light-Oxygen-Voltage Receptor Integrates Light and Temperature.
J.Mol.Biol., 433, 2021

 

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