8OLG
| DI2 Abeta fibril from tg-SwDI mouse | Descriptor: | Amyloid-beta protein 42 | Authors: | Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F. | Deposit date: | 2023-03-30 | Release date: | 2023-11-29 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nat.Neurosci., 26, 2023
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5D1M
| Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (P199A) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, ... | Authors: | Liang, Y.-H, Li, S, Weissman, A.M, Ji, X. | Deposit date: | 2015-08-04 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.581 Å) | Cite: | Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B. J.Biol.Chem., 290, 2015
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5ICQ
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6RH3
| Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | Deposit date: | 2019-04-18 | Release date: | 2019-07-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation. Mol.Cell, 75, 2019
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5WBC
| Designed Artificial Cupredoxins - WT | Descriptor: | ACETATE ION, GLYCEROL, Streptavidin, ... | Authors: | Mann, S.I, Heinisch, T, Weitz, A.C, Hendrich, M.R, Ward, T.R, Borovik, A.S. | Deposit date: | 2017-06-28 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Modular Artificial Cupredoxins. J. Am. Chem. Soc., 138, 2016
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5WDI
| Structure of Human Sts-2 histidine phosphatase domain | Descriptor: | SULFATE ION, Ubiquitin-associated and SH3 domain-containing protein A | Authors: | Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B. | Deposit date: | 2017-07-05 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2. Biochemistry, 56, 2017
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5W5G
| Structure of Human Sts-1 histidine phosphatase domain | Descriptor: | Ubiquitin-associated and SH3 domain-containing protein B | Authors: | Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B. | Deposit date: | 2017-06-15 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2. Biochemistry, 56, 2017
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8OYI
| particulate methane monooxygenase with 2,2,2-trifluoroethanol bound | Descriptor: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ... | Authors: | Tucci, F.J, Rosenzweig, A.C. | Deposit date: | 2023-05-04 | Release date: | 2023-11-08 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.19 Å) | Cite: | Product analog binding identifies the copper active site of particulate methane monooxygenase. Nat Catal, 6, 2023
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6FLQ
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6HAM
| Adenylate kinase | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE | Authors: | Kantaev, R, Inbal, R, Goldenzweig, A, Barak, Y, Dym, O, Peleg, Y, Albek, S, Fleishman, S.J, Haran, G. | Deposit date: | 2018-08-08 | Release date: | 2019-08-28 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Manipulating the Folding Landscape of a Multidomain Protein. J.Phys.Chem.B, 122, 2018
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6HAP
| Adenylate kinase | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE | Authors: | Kantaev, R, Inbal, R, Goldenzweig, A, Barak, Y, Dym, O, Peleg, Y, Albek, S, Fleishman, S.J, Haran, G. | Deposit date: | 2018-08-08 | Release date: | 2019-08-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Manipulating the Folding Landscape of a Multidomain Protein. J.Phys.Chem.B, 122, 2018
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6CPD
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6DAM
| Crystal structure of lanthanide-dependent methanol dehydrogenase XoxF from Methylomicrobium buryatense 5G | Descriptor: | LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF, PYRROLOQUINOLINE QUINONE, ... | Authors: | Deng, Y, Ro, S.Y, Rosenzweig, A.C. | Deposit date: | 2018-05-01 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and function of the lanthanide-dependent methanol dehydrogenase XoxF from the methanotroph Methylomicrobium buryatense 5GB1C. J. Biol. Inorg. Chem., 23, 2018
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4YDX
| Crystal structure of cisplatin bound to a human copper chaperone (monomer) - new refinement | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, Copper transport protein ATOX1, PLATINUM (II) ION, ... | Authors: | Shabalin, I.G, Boal, A.K, Dauter, Z, Jaskolski, M, Minor, W, Rosenzweig, A.C, Wlodawer, A. | Deposit date: | 2015-02-23 | Release date: | 2015-03-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr.,Sect.D, 71, 2015
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6E1C
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1WQ1
| RAS-RASGAP COMPLEX | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, H-RAS, ... | Authors: | Scheffzek, K, Ahmadian, M.R, Kabsch, W, Wiesmueller, L, Lautwein, A, Schmitz, F, Wittinghofer, A. | Deposit date: | 1997-07-03 | Release date: | 1998-07-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science, 277, 1997
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6FOG
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6FOH
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1AIO
| CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA CONTAINING THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN | Descriptor: | Cisplatin, DNA (5'-D(*CP*CP*(BRU)P*CP*TP*[PT(NH3)2(GP*GP)]*TP*CP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3') | Authors: | Takahara, P.M, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J. | Deposit date: | 1997-04-23 | Release date: | 1997-04-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin. Nature, 377, 1995
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1X8N
| 1.08 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Complexed With Nitric Oxide at pH 7.4 | Descriptor: | NITRIC OXIDE, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kondrashov, D.A, Roberts, S.A, Weichsel, A, Montfort, W.R. | Deposit date: | 2004-08-18 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding Biochemistry, 43, 2004
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1X8O
| 1.01 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Complexed With Nitric Oxide at pH 5.6 | Descriptor: | NITRIC OXIDE, Nitrophorin 4, PHOSPHATE ION, ... | Authors: | Kondrashov, D.A, Roberts, S.A, Weichsel, A, Montfort, W.R. | Deposit date: | 2004-08-18 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.01 Å) | Cite: | Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding Biochemistry, 43, 2004
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1X8Q
| 0.85 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus in Complex with Water at pH 5.6 | Descriptor: | Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kondrashov, D.A, Roberts, S.A, Weichsel, A, Montfort, W.R. | Deposit date: | 2004-08-18 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding Biochemistry, 43, 2004
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6FVT
| 26S proteasome, s1 state | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | Authors: | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | Deposit date: | 2018-03-05 | Release date: | 2018-08-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating. Cell Rep, 24, 2018
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1U0X
| Crystal structure of nitrophorin 4 under pressure of xenon (200 psi) | Descriptor: | AMMONIA, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Nienhaus, K, Maes, E.M, Weichsel, A, Montfort, W.R, Nienhaus, G.U. | Deposit date: | 2004-07-14 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural dynamics controls nitric oxide affinity in nitrophorin 4 J.Biol.Chem., 279, 2004
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6FVW
| 26S proteasome, s4 state | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | Authors: | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | Deposit date: | 2018-03-05 | Release date: | 2018-08-29 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating. Cell Rep, 24, 2018
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