8FZA
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![BU of 8fza by Molmil](/molmil-images/mine/8fza) | Class I type III preQ1 riboswitch from E. coli | Descriptor: | 7-DEAZA-7-AMINOMETHYL-GUANINE, MANGANESE (II) ION, PreQ1 Riboswitch (30-MER) | Authors: | Wedekind, J.E, Schroeder, G.M, Jenkins, J.L. | Deposit date: | 2023-01-27 | Release date: | 2023-08-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and function analysis of a type III preQ 1 -I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence. J.Biol.Chem., 299, 2023
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1EBH
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![BU of 1ebh by Molmil](/molmil-images/mine/1ebh) | |
8FB3
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![BU of 8fb3 by Molmil](/molmil-images/mine/8fb3) | |
1EBG
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![BU of 1ebg by Molmil](/molmil-images/mine/1ebg) | |
1HXQ
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![BU of 1hxq by Molmil](/molmil-images/mine/1hxq) | THE STRUCTURE OF NUCLEOTIDYLATED GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE FROM ESCHERICHIA COLI AT 1.86 ANGSTROMS RESOLUTION | Descriptor: | FE (III) ION, HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Wedekind, J.E, Frey, P.A, Rayment, I. | Deposit date: | 1996-06-16 | Release date: | 1997-10-22 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | The structure of nucleotidylated histidine-166 of galactose-1-phosphate uridylyltransferase provides insight into phosphoryl group transfer. Biochemistry, 35, 1996
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1HXP
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![BU of 1hxp by Molmil](/molmil-images/mine/1hxp) | NUCLEOTIDE TRANSFERASE | Descriptor: | BETA-MERCAPTOETHANOL, FE (III) ION, HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, ... | Authors: | Wedekind, J.E, Frey, P.A, Rayment, I. | Deposit date: | 1995-06-09 | Release date: | 1996-11-08 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A resolution. Biochemistry, 34, 1995
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4RZD
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![BU of 4rzd by Molmil](/molmil-images/mine/4rzd) | Crystal Structure of a PreQ1 Riboswitch | Descriptor: | 7-DEAZA-7-AMINOMETHYL-GUANINE, PreQ1-III Riboswitch (Class 3) | Authors: | Wedekind, J.E, Liberman, J.A, Salim, M. | Deposit date: | 2014-12-20 | Release date: | 2015-07-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics. Proc.Natl.Acad.Sci.USA, 112, 2015
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5D5L
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![BU of 5d5l by Molmil](/molmil-images/mine/5d5l) | |
3Q51
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![BU of 3q51 by Molmil](/molmil-images/mine/3q51) | |
1NUV
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![BU of 1nuv by Molmil](/molmil-images/mine/1nuv) | The Leadzyme Ribozyme Bound to Mg(H2O)6(II) and Sr(II) at 1.8 A resolution | Descriptor: | 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Wedekind, J.E, Mckay, D.B. | Deposit date: | 2003-02-01 | Release date: | 2003-08-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications
for catalytic mechanism and allo site ion regulation. BIOCHEMISTRY, 42, 2003
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1NUJ
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![BU of 1nuj by Molmil](/molmil-images/mine/1nuj) | THE LEADZYME STRUCTURE BOUND TO MG(H20)6(II) AT 1.8 A RESOLUTION | Descriptor: | 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION | Authors: | Wedekind, J.E, Mckay, D.B. | Deposit date: | 2003-01-31 | Release date: | 2003-08-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications
for catalytic mechanism and allo site ion regulation. BIOCHEMISTRY, 42, 2003
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4JCG
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![BU of 4jcg by Molmil](/molmil-images/mine/4jcg) | Recombinant wild type Nitrosomonas europaea cytochrome c552 | Descriptor: | Cytochrome c-552, HEME C | Authors: | Wedekind, J.E, Can, M, Krucinska, J, Bren, K.L. | Deposit date: | 2013-02-21 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural Characterization of Nitrosomonas europaea Cytochrome c-552 Variants with Marked Differences in Electronic Structure. Chembiochem, 14, 2013
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1ZFX
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![BU of 1zfx by Molmil](/molmil-images/mine/1zfx) | The Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage site | Descriptor: | 5'-R(*CP*GP*GP*UP*GP*AP*UP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | Authors: | Wedekind, J.E. | Deposit date: | 2005-04-20 | Release date: | 2006-02-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer. Biochemistry, 45, 2006
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1ZFT
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1ZFV
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![BU of 1zfv by Molmil](/molmil-images/mine/1zfv) | The structure of an all-RNA minimal Hairpin Ribozyme with Mutation G8A at the cleavage site | Descriptor: | 5'-R(*CP*GP*GP*UP*GP*AP*AP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | Authors: | Wedekind, J.E. | Deposit date: | 2005-04-20 | Release date: | 2006-02-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer. Biochemistry, 45, 2006
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429D
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![BU of 429d by Molmil](/molmil-images/mine/429d) | |
3I2S
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![BU of 3i2s by Molmil](/molmil-images/mine/3i2s) | Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10 | Descriptor: | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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3I2R
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![BU of 3i2r by Molmil](/molmil-images/mine/3i2r) | Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9 | Descriptor: | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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3I2Q
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![BU of 3i2q by Molmil](/molmil-images/mine/3i2q) | Crystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9 | Descriptor: | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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3I2U
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![BU of 3i2u by Molmil](/molmil-images/mine/3i2u) | Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10 | Descriptor: | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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2OUE
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![BU of 2oue by Molmil](/molmil-images/mine/2oue) | |
3CQS
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![BU of 3cqs by Molmil](/molmil-images/mine/3cqs) | A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases | Descriptor: | 13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 19-mer ribozyme strand, ... | Authors: | Torelli, A.T, Spitale, R.C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2008-04-03 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme Biochem.Biophys.Res.Commun., 371, 2008
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4FXW
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![BU of 4fxw by Molmil](/molmil-images/mine/4fxw) | Structure of phosphorylated SF1 complex with U2AF65-UHM domain | Descriptor: | SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit | Authors: | Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. | Deposit date: | 2012-07-03 | Release date: | 2013-01-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
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7REX
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![BU of 7rex by Molmil](/molmil-images/mine/7rex) | |
6XH0
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![BU of 6xh0 by Molmil](/molmil-images/mine/6xh0) | |