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PDB: 77 件
8FB3
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PreQ1-1 (type-1) riboswitch with stacked metabolites and a C10-G34 base pair in the expression platform
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, MAGNESIUM ION, RNA (34-MER) Riboswitch
著者Wedekind, J.E, Schroeder, G.M, Jenkins, J.L.
登録日2022-11-29
公開日2023-02-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A riboswitch separated from its ribosome-binding site still regulates translation.
Nucleic Acids Res., 51, 2023
3Q51
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Structural analysis of a class I PreQ1 riboswitch aptamer in the metabolite-free state.
分子名称: MAGNESIUM ION, PREQ1 RIBOSWITCH, SULFATE ION
著者Wedekind, J.E, Jenkins, J.L, Krucinska, J.
登録日2010-12-26
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation.
J.Biol.Chem., 286, 2011
8FZA
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Class I type III preQ1 riboswitch from E. coli
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, MANGANESE (II) ION, PreQ1 Riboswitch (30-MER)
著者Wedekind, J.E, Schroeder, G.M, Jenkins, J.L.
登録日2023-01-27
公開日2023-08-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and function analysis of a type III preQ 1 -I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence.
J.Biol.Chem., 299, 2023
1EBH
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OCTAHEDRAL COORDINATION AT THE HIGH AFFINITY METAL SITE IN ENOLASE; CRYSTALLOGRAPHIC ANALYSIS OF THE MG++-ENZYME FROM YEAST AT 1.9 ANGSTROMS RESOLUTION
分子名称: CHLORIDE ION, ENOLASE, MAGNESIUM ION
著者Wedekind, J.E, Reed, G.H, Rayment, I.
登録日1994-11-01
公開日1995-04-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Octahedral coordination at the high-affinity metal site in enolase: crystallographic analysis of the MgII--enzyme complex from yeast at 1.9 A resolution.
Biochemistry, 34, 1995
1HXQ
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THE STRUCTURE OF NUCLEOTIDYLATED GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE FROM ESCHERICHIA COLI AT 1.86 ANGSTROMS RESOLUTION
分子名称: FE (III) ION, HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE, ...
著者Wedekind, J.E, Frey, P.A, Rayment, I.
登録日1996-06-16
公開日1997-10-22
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The structure of nucleotidylated histidine-166 of galactose-1-phosphate uridylyltransferase provides insight into phosphoryl group transfer.
Biochemistry, 35, 1996
5D5L
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BU of 5d5l by Molmil
PreQ1-II riboswitch with an engineered G-U wobble pair bound to Cs+
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, CESIUM ION, MAGNESIUM ION, ...
著者Wedekind, J.E, Liberman, J.A, Salim, M.
登録日2015-08-10
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cesium(I) binding to G-U-wobble base pairs in preQ1 riboswitches with implications for crystallographic phasing
to be published
4RZD
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Crystal Structure of a PreQ1 Riboswitch
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, PreQ1-III Riboswitch (Class 3)
著者Wedekind, J.E, Liberman, J.A, Salim, M.
登録日2014-12-20
公開日2015-07-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics.
Proc.Natl.Acad.Sci.USA, 112, 2015
1HXP
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NUCLEOTIDE TRANSFERASE
分子名称: BETA-MERCAPTOETHANOL, FE (III) ION, HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, ...
著者Wedekind, J.E, Frey, P.A, Rayment, I.
登録日1995-06-09
公開日1996-11-08
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A resolution.
Biochemistry, 34, 1995
1NUV
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The Leadzyme Ribozyme Bound to Mg(H2O)6(II) and Sr(II) at 1.8 A resolution
分子名称: 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION, ...
著者Wedekind, J.E, Mckay, D.B.
登録日2003-02-01
公開日2003-08-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation.
BIOCHEMISTRY, 42, 2003
1NUJ
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THE LEADZYME STRUCTURE BOUND TO MG(H20)6(II) AT 1.8 A RESOLUTION
分子名称: 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION
著者Wedekind, J.E, Mckay, D.B.
登録日2003-01-31
公開日2003-08-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation.
BIOCHEMISTRY, 42, 2003
1EBG
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BU of 1ebg by Molmil
CHELATION OF SER 39 TO MG2+ LATCHES A GATE AT THE ACTIVE SITE OF ENOLASE: STRUCTURE OF THE BIS(MG2+) COMPLEX OF YEAST ENOLASE AND THE INTERMEDIATE ANALOG PHOSPHONOACETOHYDROXAMATE AT 2.1 ANGSTROMS RESOLUTION
分子名称: ENOLASE, MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID
著者Wedekind, J.E, Reed, G.H, Rayment, I.
登録日1994-04-27
公開日1995-04-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Chelation of serine 39 to Mg2+ latches a gate at the active site of enolase: structure of the bis(Mg2+) complex of yeast enolase and the intermediate analog phosphonoacetohydroxamate at 2.1-A resolution.
Biochemistry, 33, 1994
1ZFV
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The structure of an all-RNA minimal Hairpin Ribozyme with Mutation G8A at the cleavage site
分子名称: 5'-R(*CP*GP*GP*UP*GP*AP*AP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ...
著者Wedekind, J.E.
登録日2005-04-20
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
1ZFX
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The Structure of a minimal all-RNA Hairpin Ribozyme with the mutant G8U at the cleavage site
分子名称: 5'-R(*CP*GP*GP*UP*GP*AP*UP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ...
著者Wedekind, J.E.
登録日2005-04-20
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
1ZFT
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BU of 1zft by Molmil
The crystal structure of an all-RNA minimal Hairpin Ribozyme with mutant G8I at the cleavage site
分子名称: 5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ...
著者Wedekind, J.E.
登録日2005-04-20
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
429D
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BU of 429d by Molmil
CRYSTAL STRUCTURE OF A LEADZYME; METAL BINDING AND IMPLICATIONS FOR CATALYSIS
分子名称: MAGNESIUM ION, RNA (5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3'), RNA (5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3')
著者Wedekind, J.E, McKay, D.B.
登録日1998-09-29
公開日1999-03-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a lead-dependent ribozyme revealing metal binding sites relevant to catalysis.
Nat.Struct.Biol., 6, 1999
3I2S
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BU of 3i2s by Molmil
Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10
分子名称: 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ...
著者Wedekind, J.E, Spitale, R.C, Krucinska, J.
登録日2009-06-29
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.
Biochemistry, 48, 2009
3I2R
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Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9
分子名称: 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ...
著者Wedekind, J.E, Spitale, R.C, Krucinska, J.
登録日2009-06-29
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.
Biochemistry, 48, 2009
3I2Q
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Crystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9
分子名称: 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ...
著者Wedekind, J.E, Spitale, R.C, Krucinska, J.
登録日2009-06-29
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.
Biochemistry, 48, 2009
3I2U
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Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10
分子名称: 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ...
著者Wedekind, J.E, Spitale, R.C, Krucinska, J.
登録日2009-06-29
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.
Biochemistry, 48, 2009
2OUE
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Crystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolution
分子名称: COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ...
著者Wedekind, J.E.
登録日2007-02-10
公開日2007-03-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
4JCG
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BU of 4jcg by Molmil
Recombinant wild type Nitrosomonas europaea cytochrome c552
分子名称: Cytochrome c-552, HEME C
著者Wedekind, J.E, Can, M, Krucinska, J, Bren, K.L.
登録日2013-02-21
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Characterization of Nitrosomonas europaea Cytochrome c-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
7REX
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PreQ1-1 (type-1) riboswitch in complex with tandem stacked metabolites
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, MAGNESIUM ION, RNA (34-MER)
著者Jenkins, J.L, Schroeder, G.M, Wedekind, J.E.
登録日2021-07-13
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
Nat Commun, 13, 2022
8TOZ
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Class III PreQ1 riboswitch double mutant U8C/A85G
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, Class-III preQ1 riboswitch
著者Srivastava, Y, Jenkins, J.L, Wedekind, J.E.
登録日2023-08-04
公開日2024-08-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献New insights into Class III PreQ1 metabolite binding
To Be Published
3Q50
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Structural analysis of a class I PreQ1 riboswitch aptamer in the metabolite-bound state
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, PREQ1 RIBOSWITCH, SULFATE ION
著者Jenkins, J.L, Krucinska, J, Wedekind, J.E.
登録日2010-12-26
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation.
J.Biol.Chem., 286, 2011
2FGP
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Crystal structure of a minimal, all RNA hairpin ribozyme with modifications (g8dap, u39c) at ph 8.6
分子名称: 5'-R(*CP*GP*GP*UP*GP*AP*(N6G)P*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ...
著者Salter, J.D, Wedekind, J.E.
登録日2005-12-22
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006

 

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