3PJ6
 
 | | Crystal Structures of Multidrug-Resistant Clinical Isolate 769 HIV-1 Protease Variants | | 分子名称: | HIV protease | | 著者 | Yedidi, R.S, Proteasa, G, Martinez-Cajas, J.L, Vickrey, J.F, Martin, P.D, Wawrzak, Z, Kovari, L.C. | | 登録日 | 2010-11-08 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants.
Acta Crystallogr.,Sect.D, 67, 2011
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6AOO
 | | 2.15 Angstrom Resolution Crystal Structure of Malate Dehydrogenase from Haemophilus influenzae | | 分子名称: | Malate dehydrogenase, SULFATE ION | | 著者 | Minasov, G, Wawrzak, Z, Skarina, T, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-08-16 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | 2.15 Angstrom Resolution Crystal Structure of Malate Dehydrogenase from Haemophilus influenzae.
To Be Published
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6BNF
 | | Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, mono-zinc complex | | 分子名称: | ACETATE ION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Di Leo, R, Savchenko, A, Anderson, W.F, Satchell, K.J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-11-16 | | 公開日 | 2018-01-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis.
ACS Chem. Biol., 2018
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6B3P
 | | Crystal structure of CBMbc (family CBM26) from Eubacterium rectale Amy13K in Complex with Maltoheptaose | | 分子名称: | 1,2-ETHANEDIOL, Amy13K, FORMIC ACID, ... | | 著者 | Cockburn, D.W, Wawrzak, Z, Perez Medina, K, Koropatkin, N.M. | | 登録日 | 2017-09-22 | | 公開日 | 2017-11-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Novel carbohydrate binding modules in the surface anchored alpha-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut.
Mol. Microbiol., 107, 2018
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6BNC
 | | Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, Thr315Ala mutant di-zinc and PEG complex | | 分子名称: | CHLORIDE ION, POLYETHYLENE GLYCOL (N=34), Phosphoethanolamine transferase, ... | | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Savchenko, A, Anderson, W.F, Satchell, K.J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-11-16 | | 公開日 | 2018-01-31 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis.
ACS Chem. Biol., 13, 2018
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6AZI
 | | 1.75 Angstrom Resolution Crystal Structure of D-alanyl-D-alanine Endopeptidase from Enterobacter cloacae in Complex with Covalently Bound Boronic Acid | | 分子名称: | BORATE ION, D-alanyl-D-alanine endopeptidase | | 著者 | Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-09-11 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-05-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | 1.75 Angstrom Resolution Crystal Structure of D-alanyl-D-alanine Endopeptidase from Enterobacter cloacae in Complex with Covalently Bound Boronic Acid.
To be Published
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6AZ5
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4MJZ
 | | 2.75 Angstrom Resolution Crystal Structure of Putative Orotidine-monophosphate-decarboxylase from Toxoplasma gondii. | | 分子名称: | DI(HYDROXYETHYL)ETHER, NITRATE ION, Orotidine 5'-phosphate decarboxylase, ... | | 著者 | Minasov, G, Wawrzak, Z, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-09-04 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | 2.75 Angstrom Resolution Crystal Structure of Putative Orotidine-monophosphate-decarboxylase from Toxoplasma gondii.
TO BE PUBLISHED
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3IFS
 | | 2.0 Angstrom Resolution Crystal Structure of Glucose-6-phosphate Isomerase (pgi) from Bacillus anthracis. | | 分子名称: | CHLORIDE ION, Glucose-6-phosphate isomerase, LITHIUM ION, ... | | 著者 | Minasov, G, Wawrzak, Z, Onopriyenko, O, Gordon, E, Peterson, S.N, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-07-24 | | 公開日 | 2009-08-11 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | | 主引用文献 | 2.0 Angstrom Resolution Crystal Structure of Glucose-6-phosphate Isomerase (pgi) from Bacillus anthracis.
To be Published
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3IG4
 | | Structure of a putative aminopeptidase P from Bacillus anthracis | | 分子名称: | MANGANESE (II) ION, SULFATE ION, Xaa-pro aminopeptidase | | 著者 | Anderson, S.M, Wawrzak, Z, Skarina, T, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-07-27 | | 公開日 | 2009-08-04 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure of a putative aminopeptidase P from Bacillus anthracis
To be Published
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3IMI
 | | 2.01 Angstrom resolution crystal structure of a HIT family protein from Bacillus anthracis str. 'Ames Ancestor' | | 分子名称: | HIT family protein, SULFATE ION, ZINC ION | | 著者 | Halavaty, A.S, Wawrzak, Z, Skarina, T, Onopriyenko, O, Gordon, E, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-08-10 | | 公開日 | 2009-08-18 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | 2.01 Angstrom resolution crystal structure of a HIT family protein from Bacillus anthracis str. 'Ames Ancestor'
To be Published
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4NVR
 | | 2.22 Angstrom Resolution Crystal Structure of a Putative Acyltransferase from Salmonella enterica | | 分子名称: | CALCIUM ION, CHLORIDE ION, Putative acyltransferase | | 著者 | Minasov, G, Wawrzak, Z, Skarina, T, Gordon, E, Stam, J, Kwon, K, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-12-05 | | 公開日 | 2013-12-18 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | 2.22 Angstrom Resolution Crystal Structure of a Putative Acyltransferase from Salmonella enterica.
TO BE PUBLISHED
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3KBO
 | | 2.14 Angstrom Crystal Structure of Putative Oxidoreductase (ycdW) from Salmonella typhimurium in Complex with NADP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Glyoxylate/hydroxypyruvate reductase A, ... | | 著者 | Minasov, G, Wawrzak, Z, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-10-20 | | 公開日 | 2009-10-27 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | 2.14 Angstrom Crystal Structure of Putative Oxidoreductase (ycdW) from Salmonella typhimurium in Complex with NADP.
To be Published
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3L4D
 | | Crystal structure of sterol 14-alpha demethylase (CYP51) from Leishmania infantum in complex with fluconazole | | 分子名称: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-12-19 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Substrate Preferences and Catalytic Parameters Determined by Structural Characteristics of Sterol 14{alpha}-Demethylase (CYP51) from Leishmania infantum.
J.Biol.Chem., 286, 2011
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3KSW
 | | Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with an inhibitor VNF ((4-(4-chlorophenyl)-N-[2-(1H-imidazol-1-yl)-1-phenylethyl]benzamide) | | 分子名称: | 4'-chloro-N-[(1R)-2-(1H-imidazol-1-yl)-1-phenylethyl]biphenyl-4-carboxamide, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha demethylase | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-11-23 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi.
J.Biol.Chem., 285, 2010
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4OFX
 | | Crystal Structure of a Putative Cystathionine beta-Synthase from Coxiella burnetii | | 分子名称: | Cystathionine beta-synthase, SODIUM ION | | 著者 | Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-01-15 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal Structure of a Putative Cystathionine beta-Synthase from Coxiella burnetii
To be Published
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4N3O
 | | 2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni. | | 分子名称: | CALCIUM ION, Putative D-glycero-D-manno-heptose 7-phosphate kinase | | 著者 | Minasov, G, Wawrzak, Z, Gordon, E, Onopriyenko, O, Grimshaw, S, Kwon, K, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-10-07 | | 公開日 | 2013-10-16 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni.
TO BE PUBLISHED
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5HT0
 | | Crystal structure of an Antibiotic_NAT family aminoglycoside acetyltransferase HMB0038 from an uncultured soil metagenomic sample in complex with coenzyme A | | 分子名称: | Aminoglycoside acetyltransferase HMB0005, COENZYME A, SULFATE ION | | 著者 | Xu, Z, Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-01-26 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.752 Å) | | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
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5HMN
 | | Crystal structure of an aminoglycoside acetyltransferase HMB0005 from an uncultured soil metagenomic sample, unknown active site density modeled as polyethylene glycol | | 分子名称: | AAC3-I, COENZYME A, TETRAETHYLENE GLYCOL | | 著者 | Xu, Z, Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-01-16 | | 公開日 | 2016-02-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.018 Å) | | 主引用文献 | Crystal structure of an aminoglycoside acetyltransferase HMB0005 from an uncultured soil metagenomic sample, unknown active site density modeled as polyethylene glycol
To Be Published
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3K1S
 | | Crystal Structure of the PTS Cellobiose Specific Enzyme IIA from Bacillus anthracis | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PTS system, ... | | 著者 | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-09-28 | | 公開日 | 2009-10-13 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the PTS Cellobiose Specific Enzyme IIA from Bacillus anthracis
To be Published
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4MLG
 | | Structure of RS223-Beta-xylosidase | | 分子名称: | Beta-xylosidase, CALCIUM ION, SULFATE ION | | 著者 | Jordan, D, Braker, J, Wagschal, K, Lee, C, Dubrovska, I, Anderson, S, Wawrzak, Z. | | 登録日 | 2013-09-06 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of RS223-Beta-xylosidase
To be Published
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3L8L
 | | Gramicidin D complex with sodium iodide | | 分子名称: | GRAMICIDIN D, IODIDE ION, METHANOL, ... | | 著者 | Olczak, A, Glowka, M.L, Szczesio, M, Bojarska, J, Wawrzak, Z, Duax, W.L. | | 登録日 | 2009-12-31 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The first crystal structure of a gramicidin complex with sodium: high-resolution study of a nonstoichiometric gramicidin D-NaI complex.
Acta Crystallogr.,Sect.D, 66, 2010
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4O96
 | | 2.60 Angstrom resolution crystal structure of a protein kinase domain of type III effector NleH2 (ECs1814) from Escherichia coli O157:H7 str. Sakai | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, type III effector protein kinase | | 著者 | Anderson, S.M, Halavaty, A.S, Wawrzak, Z, Kudritska, M, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-01-01 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Type III Effector NleH2 from Escherichia coli O157:H7 str. Sakai Features an Atypical Protein Kinase Domain.
Biochemistry, 53, 2014
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3K1O
 | | Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole | | 分子名称: | 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-6-O-{4-[4-(4-{1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenyl}-1-(1H-1,2,4-triazol-1-yl)-D-erythro-hexitol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14 alpha-demethylase | | 著者 | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | | 登録日 | 2009-09-28 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi.
J.Biol.Chem., 285, 2010
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3LAC
 | | Crystal structure of Bacillus anthracis pyrrolidone-carboxylate peptidase, pcP | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Pyrrolidone-carboxylate peptidase | | 著者 | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Hasseman, J, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-01-06 | | 公開日 | 2010-01-19 | | 最終更新日 | 2011-12-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of Bacillus anthracis pyrrolidone-carboxylate peptidase, pcP
To be Published
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