7E4I
 
 | | Cryo-EM structure of the yeast mitochondrial SAM-Tom40/Tom5/Tom6 complex at 3.0 angstrom | | Descriptor: | Mitochondrial import receptor subunit TOM40, Mitochondrial import receptor subunit TOM5, Mitochondrial import receptor subunit TOM6, ... | | Authors: | Wang, Q, Guan, Z.Y, Qi, L.B, Yan, C.Y, Yin, P. | | Deposit date: | 2021-02-13 | | Release date: | 2021-09-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Structural insight into the SAM-mediated assembly of the mitochondrial TOM core complex.
Science, 373, 2021
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6K83
 | | Structure of RGLG1 mutant-D207G | | Descriptor: | CALCIUM ION, E3 ubiquitin-protein ligase RGLG1, MAGNESIUM ION | | Authors: | Wang, Q, Wu, Y. | | Deposit date: | 2019-06-11 | | Release date: | 2020-06-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | RGLG1 mutant-D207G
To Be Published
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6K86
 | | The closed state of RGLG1 mutant-E378A | | Descriptor: | E3 ubiquitin-protein ligase RGLG1, MAGNESIUM ION, SODIUM ION | | Authors: | Wang, Q, Wu, Y. | | Deposit date: | 2019-06-11 | | Release date: | 2020-06-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.593 Å) | | Cite: | The closed state of RGLG1 mutant-E378A
To Be Published
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6K8B
 | | The open state of RGLG1 VWA domain | | Descriptor: | CALCIUM ION, E3 ubiquitin-protein ligase RGLG1, MAGNESIUM ION | | Authors: | Wang, Q, Wu, Y. | | Deposit date: | 2019-06-11 | | Release date: | 2020-06-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | The open state of RGLG1 VWA domain
To Be Published
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5XYB
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5Y24
 | | Crystal structure of AimR from Bacillus phage SPbeta in complex with its signalling peptide | | Descriptor: | AimR transcriptional regulator, BROMIDE ION, GLY-MET-PRO-ARG-GLY-ALA | | Authors: | Wang, Q, Guan, Z.Y, Zou, T.T, Yin, P. | | Deposit date: | 2017-07-24 | | Release date: | 2018-09-19 | | Last modified: | 2018-11-28 | | Method: | X-RAY DIFFRACTION (1.922 Å) | | Cite: | Structural basis of the arbitrium peptide-AimR communication system in the phage lysis-lysogeny decision.
Nat Microbiol, 3, 2018
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6AEE
 | | Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G | | Descriptor: | 9 Mer Peptide (RL9) From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Wang, Q, Song, H, Qi, J, Gao, G.F. | | Deposit date: | 2018-08-04 | | Release date: | 2019-07-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.303 Å) | | Cite: | Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex.
Cell. Mol. Immunol., 2019
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6AED
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8HMG
 | | The open state of RGLG2-VWA | | Descriptor: | CALCIUM ION, E3 ubiquitin-protein ligase RGLG2, MAGNESIUM ION, ... | | Authors: | Wang, Q. | | Deposit date: | 2022-12-03 | | Release date: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Ca2+-based Allosteric Switches and Shape Shifting in RGLG1 VWA domain
To Be Published
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8HMH
 | | The closed state of RGLG2-VWA | | Descriptor: | E3 ubiquitin-protein ligase RGLG2, MAGNESIUM ION | | Authors: | Wang, Q. | | Deposit date: | 2022-12-03 | | Release date: | 2023-12-27 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | The regulation of RGLG2-VWA by Ca 2+ ions.
Biochim Biophys Acta Proteins Proteom, 1872, 2024
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7D58
 | | cryo-EM structure of human RNA polymerase III in elongating state | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | | Deposit date: | 2020-09-25 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
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7D59
 | | cryo-EM structure of human RNA polymerase III in apo state | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | | Deposit date: | 2020-09-25 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
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5YGU
 | | Crystal structure of Escherichia coli (strain K12) mRNA Decapping Complex RppH-DapF | | Descriptor: | Diaminopimelate epimerase, IODIDE ION, L(+)-TARTARIC ACID, ... | | Authors: | Wang, Q, Guan, Z.Y, Zhang, D.L, Zou, T.T, Yin, P. | | Deposit date: | 2017-09-27 | | Release date: | 2018-06-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | DapF stabilizes the substrate-favoring conformation of RppH to stimulate its RNA-pyrophosphohydrolase activity in Escherichia coli.
Nucleic Acids Res., 46, 2018
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5YWJ
 | | Global regulatory element SarX | | Descriptor: | HTH-type transcriptional regulator SarX | | Authors: | Wang, Q. | | Deposit date: | 2017-11-29 | | Release date: | 2018-12-05 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Crystal structure of SarX from Staphylococcus aureus
To Be Published
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5ZY5
 | | spCOMT apo structure | | Descriptor: | Probable catechol O-methyltransferase 1 | | Authors: | Wang, Q, Xu, L. | | Deposit date: | 2018-05-22 | | Release date: | 2019-05-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.295 Å) | | Cite: | structural and functional investigations of spCOMT
To Be Published
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5ZY6
 | | catechol methyltransferase spCOMT | | Descriptor: | Probable catechol O-methyltransferase 1, S-ADENOSYLMETHIONINE | | Authors: | Wang, Q, Xu, L. | | Deposit date: | 2018-05-22 | | Release date: | 2019-05-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | structural insight into spCOMT
To Be Published
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8IHO
 | | Crystal structures of SARS-CoV-2 papain-like protease in complex with covalent inhibitors | | Descriptor: | Papain-like protease nsp3, ZINC ION, covalent inhibitor | | Authors: | Wang, Q, Hu, H, Li, M, Xu, Y. | | Deposit date: | 2023-02-23 | | Release date: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease.
Int J Mol Sci, 24, 2023
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7VG3
 | | Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA | | Descriptor: | CALCIUM ION, Dicer-like 3, TAS1a RNA forward strand (5'-phosphorylated), ... | | Authors: | Wang, Q, Du, J. | | Deposit date: | 2021-09-14 | | Release date: | 2021-10-27 | | Last modified: | 2021-12-15 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
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7VG2
 | | Cryo-EM structure of Arabidopsis DCL3 in complex with a 40-bp RNA | | Descriptor: | CALCIUM ION, Dicer-like 3, TAS1a forward strand (5'-phosphorylation), ... | | Authors: | Wang, Q, Du, J. | | Deposit date: | 2021-09-14 | | Release date: | 2021-10-27 | | Last modified: | 2021-12-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
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7Y9K
 | | Crystal structure of P450 BM3-TMK from Bacillus megaterium | | Descriptor: | Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-25 | | Release date: | 2023-06-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Engineering of a P450-based Kemp eliminase with a new mechanism
Chinese J Catal, 47, 2023
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7Y9J
 | | Crystal structure of P450 BM3-TMK from Bacillus megaterium in complex with 5-nitro-1,2-benzisoxazole | | Descriptor: | 5-nitro-1,2-benzoxazole, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-24 | | Release date: | 2023-06-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Engineering of a P450-based Kemp eliminase with a new mechanism
Chinese J Catal, 47, 2023
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7XL7
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7Y9L
 | | Crystal structure of P450 BM3-2F from Bacillus megaterium in complex with 2-Hydroxy-5-Nitrobenzonitrile | | Descriptor: | 5-nitro-2-oxidanyl-benzenecarbonitrile, Bifunctional cytochrome P450/NADPH--P450 reductase, NICKEL (II) ION, ... | | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-25 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Crystal structure of P450 BM3-2F from Bacillus megaterium in complex with 2-Hydroxy-5-Nitrobenzonitrile
to be published
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7Y9M
 | | Crystal structure of P450 BM3-2F from Bacillus megaterium | | Descriptor: | Bifunctional cytochrome P450/NADPH--P450 reductase, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-25 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Crystal structure of P450 BM3-2F from Bacillus megaterium
to be published
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7YTL
 | | Structure of a oxidoreductase in complex with quinone | | Descriptor: | Apoptosis inducing factor mitochondria associated 2, FLAVIN-ADENINE DINUCLEOTIDE, UBIQUINONE-1 | | Authors: | Lv, Y, Sun, Q, Wang, Q, Zhu, D. | | Deposit date: | 2022-08-15 | | Release date: | 2023-08-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Structural insights into FSP1 catalysis and ferroptosis inhibition.
Nat Commun, 14, 2023
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