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PDB: 484 件

7E2G
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Cryo-EM structure of hDisp1NNN-3C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1,Protein dispatched homolog 1
著者Li, W, Wang, L, Gong, X.
登録日2021-02-05
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
2MY9
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Solution structure of N-terminal domain of human TIG3
分子名称: Retinoic acid receptor responder protein 3
著者Wei, H, Wang, L, Xia, B.
登録日2015-01-21
公開日2015-04-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of tumor suppressors TIG3 and H-REV107.
Febs Lett., 589, 2015
4OHE
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LEOPARD Syndrome-Associated SHP2/G464A mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
4OHD
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LEOPARD Syndrome-Associated SHP2/A461T mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
4OHI
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LEOPARD Syndrome-Associated SHP2/Q510E mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
4OHL
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LEOPARD Syndrome-Associated SHP2/T468M mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
4OHH
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LEOPARD Syndrome-Associated SHP2/Q506P mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
7XC6
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Photobacterium phosphoreum fatty acid reductase complex LuxC-LuxE
分子名称: Long-chain acyl-protein thioester reductase, LuxE
著者Tian, Q, Huo, Y, Wang, L.
登録日2022-03-23
公開日2022-04-20
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Cryo-EM structure of the fatty acid reductase LuxC-LuxE complex provides insights into bacterial bioluminescence.
J.Biol.Chem., 298, 2022
2G9F
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Crystal structure of intein-tagged mouse PNGase C-terminal domain
分子名称: CHLORIDE ION, GLYCEROL, peptide N-glycanase
著者Zhou, X, Zhao, G, Wang, L, Li, G, Lennarz, W.J, Schindelin, H.
登録日2006-03-06
公開日2006-10-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2H53
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Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
分子名称: small heat shock protein Hsp26
著者White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
登録日2006-05-25
公開日2006-08-01
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (11.5 Å)
主引用文献Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2H50
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Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
分子名称: small heat shock protein Hsp26
著者White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
登録日2006-05-25
公開日2006-08-01
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (10.8 Å)
主引用文献Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2HPL
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Crystal structure of the mouse p97/PNGase complex
分子名称: C-terminal of mouse p97/VCP, PNGase
著者Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H.
登録日2006-07-17
公開日2007-05-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2HPJ
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Crystal structure of the PUB domain of mouse PNGase
分子名称: GLYCEROL, PNGase
著者Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H.
登録日2006-07-17
公開日2007-05-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2I74
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Crystal structure of mouse Peptide N-Glycanase C-terminal domain in complex with mannopentaose
分子名称: ACETATE ION, GLYCEROL, PNGase, ...
著者Zhou, X, Zhao, G, Wang, L, Li, G, Lennarz, W.J, Schindelin, H.
登録日2006-08-30
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IBJ
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Structure of House Fly Cytochrome B5
分子名称: Cytochrome b5, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L.
登録日2006-09-11
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Comparison of cytochromes b(5) from insects and vertebrates.
Proteins, 67, 2007
2I89
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Structure of septuple mutant of Rat Outer Mitochondrial Membrane Cytochrome B5
分子名称: Cytochrome b5 type B, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L, Sun, N.
登録日2006-09-01
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A histidine/tryptophan pi-stacking interaction stabilizes the heme-independent folding core of microsomal apocytochrome b5 relative to that of mitochondrial apocytochrome b5.
Biochemistry, 45, 2006
2J9I
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Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens.
分子名称: GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1
著者Wyatt, K, White, H.E, Wang, L, Bateman, O.A, Slingsby, C, Orlova, E.V, Wistow, G.
登録日2006-11-09
公開日2006-12-13
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens.
Structure, 14, 2006
2JAS
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Structure of deoxyadenosine kinase from M.mycoides with bound dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DEOXYGUANOSINE KINASE, MAGNESIUM ION
著者Welin, M, Wang, L, Eriksson, S, Eklund, H.
登録日2006-11-30
公開日2007-01-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
2JA1
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Thymidine kinase from B. cereus with TTP bound as phosphate donor.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ...
著者Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H.
登録日2006-11-17
公開日2007-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2J9R
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Thymidine kinase from B. anthracis in complex with dT.
分子名称: PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ...
著者Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H.
登録日2006-11-15
公開日2007-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2JAT
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Structure of deoxyadenosine kinase from M.mycoides with products dcmp and a flexible dcdp bound
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, DEOXYGUANOSINE KINASE, MAGNESIUM ION, ...
著者Welin, M, Wang, L, Eriksson, S, Eklund, H.
登録日2006-11-30
公開日2007-01-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
2JAQ
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Structure of deoxyadenosine kinase from M. mycoides with bound dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DEOXYGUANOSINE KINASE
著者Welin, M, Wang, L, Eriksson, S, Eklund, H.
登録日2006-11-30
公開日2007-01-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
2MI2
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Solution structure of the E. coli TatB protein in DPC micelles
分子名称: Sec-independent protein translocase protein TatB
著者Zhang, Y, Wang, L, Hu, Y, Jin, C.
登録日2013-12-08
公開日2014-04-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the TatB component of the twin-arginine translocation system.
Biochim.Biophys.Acta, 1838, 2014
2M5N
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Atomic-resolution structure of a cross-beta protofilament
分子名称: Transthyretin
著者Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M.
登録日2013-02-27
公開日2013-07-17
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5M
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Atomic-resolution structure of a triplet cross-beta amyloid fibril
分子名称: Transthyretin
著者Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M.
登録日2013-02-27
公開日2013-12-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (12.2 Å), SOLID-STATE NMR
主引用文献Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013

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