6CWE
 
 | | Structure of alpha-GSA[8,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR | | 分子名称: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(6-phenylhexyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, J, Zajonc, D. | | 登録日 | 2018-03-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Glycolipid recognition by iNKT cells
To Be Published
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3ONG
 | | Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways | | 分子名称: | SUMO-conjugating enzyme UBC9, Ubiquitin-activating enzyme E1-like | | 著者 | Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A. | | 登録日 | 2010-08-28 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
Plos One, 5, 2010
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3ONH
 | | Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways | | 分子名称: | Ubiquitin-activating enzyme E1-like | | 著者 | Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A. | | 登録日 | 2010-08-28 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
Plos One, 5, 2010
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2HSE
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8HUW
 | | Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with S217622 | | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | | 著者 | Wang, J, Zhang, J, Li, J. | | 登録日 | 2022-12-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
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7XZA
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7XZB
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7XZF
 | | Wild type of the N-terminal domain of fucoidan lyase FdlA | | 分子名称: | Fucoidan lyase, GLYCEROL, IMIDAZOLE, ... | | 著者 | Wang, J, Li, M, Pan, X. | | 登録日 | 2022-06-02 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
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7XZ8
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7XZC
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7XZD
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7XZ7
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7XZ9
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7XZE
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7CPX
 | | Lovastatin nonaketide synthase | | 分子名称: | Lovastatin nonaketide synthase, polyketide synthase component, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, J, Wang, Z. | | 登録日 | 2020-08-08 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Structural basis for the biosynthesis of lovastatin.
Nat Commun, 12, 2021
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7CPY
 | | Lovastatin nonaketide synthase with LovC | | 分子名称: | Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... | | 著者 | Wang, J, Wang, Z. | | 登録日 | 2020-08-08 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for the biosynthesis of lovastatin.
Nat Commun, 12, 2021
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2KJ1
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2KIX
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7WSB
 | | The ternary complex structure of FtmOx1 with a-ketoglutarate and 13-oxo-fumitremorgin B | | 分子名称: | 13-Oxofumitremorgin B, 2-OXOGLUTARIC ACID, COBALT (II) ION, ... | | 著者 | Wang, J, Wang, X.Y, Wang, Y.Y, Yan, W.P. | | 登録日 | 2022-01-28 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Dissecting the Mechanism of the Nonheme Iron Endoperoxidase FtmOx1 Using Substrate Analogues.
Jacs Au, 2, 2022
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8U8X
 | | crystal structure of the receptor tyrosine kinase Human HER2 (ERBB2) YVMA mutant kinase domain in complex with inhibitor compound 27 | | 分子名称: | 1-{(1R,3r,5S)-3-[(3M)-4-methyl-3-{3-methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]phenyl}-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-8-azabicyclo[3.2.1]octan-8-yl}propan-1-one, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Wang, J, Mou, T.C. | | 登録日 | 2023-09-18 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Discovery of Potent and Selective Covalent Inhibitors of HER2 WT and HER2 YVMA.
J.Med.Chem., 2024
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7CCP
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8JRL
 | | Crystal structure of P450 TleB with an indole alkaloid | | 分子名称: | (2~{S})-~{N}-[(2~{S})-1-(4-fluoranyl-1~{H}-indol-3-yl)-3-oxidanyl-propan-2-yl]-3-methyl-2-sulfanyl-butanamide, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Wang, J, Yan, W.P. | | 登録日 | 2023-06-17 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Regulation of P450 TleB catalytic flow for the synthesis of sulfur-containing indole alkaloids by substrate structure-directed strategy. and protein engineering.
Sci China Chem, 66, 2023
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6K3E
 | | LSD1/Co-Rest structure with an inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-PCPA derivative, ... | | 著者 | Wang, J. | | 登録日 | 2019-05-17 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | LSD1/Co-Rest structure with an inhibitor
To Be Published
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3PLS
 | | RON in complex with ligand AMP-PNP | | 分子名称: | MAGNESIUM ION, Macrophage-stimulating protein receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Wang, J, Steinbacher, S, Augustin, M, Schreiner, P, Epstein, D, Mulvihill, M.J, Crew, A.P. | | 登録日 | 2010-11-15 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The Crystal Structure of a Constitutively Active Mutant RON Kinase Suggests an Intramolecular Autophosphorylation Hypothesis
Biochemistry, 49, 2010
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5YNW
 | | Crystal structure of an aromatic prenyltransferase FAMD1 from Fischerella ambigua UTEX 1903 in complex with DMASPP and INN | | 分子名称: | 3-[(Z)-2-isocyanoethenyl]-1H-indole, DIMETHYLALLYL S-THIOLODIPHOSPHATE, GLYCEROL, ... | | 著者 | Wang, J, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2017-10-25 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis.
Biochem. Biophys. Res. Commun., 495, 2018
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