5I8J
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![BU of 5i8j by Molmil](/molmil-images/mine/5i8j) | Crystal structure of Dmd from phage RB69 | Descriptor: | Dmd discriminator of mRNA degradation | Authors: | Wei, Y, Zhang, H, Gao, Z.Q, Dong, Y.H. | Deposit date: | 2016-02-19 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural characterizations of phage antitoxin Dmd and its interactions with bacterial toxin RnlA Biochem. Biophys. Res. Commun., 472, 2016
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6E24
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![BU of 6e24 by Molmil](/molmil-images/mine/6e24) | Ternary structure of c-Myc-TBP-TAF1 | Descriptor: | Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein | Authors: | Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2018-07-10 | Release date: | 2019-10-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Multiple direct interactions of TBP with the MYC oncoprotein. Nat.Struct.Mol.Biol., 26, 2019
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8HMB
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![BU of 8hmb by Molmil](/molmil-images/mine/8hmb) | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with benidipine (BEN) | Descriptor: | (3R)-1-benzylpiperidin-3-yl methyl (2R,3R,4R,5R,6S)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wei, Y, Yu, Z, Zhao, Y. | Deposit date: | 2022-12-02 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors. Nat Commun, 15, 2024
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8HLP
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![BU of 8hlp by Molmil](/molmil-images/mine/8hlp) | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo) | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wei, Y, Yu, Z, Zhao, Y. | Deposit date: | 2022-11-30 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors. Nat Commun, 15, 2024
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8HMA
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![BU of 8hma by Molmil](/molmil-images/mine/8hma) | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with tetrandrine (TET) | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman, ... | Authors: | Wei, Y, Yu, Z, Zhao, Y. | Deposit date: | 2022-12-02 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors. Nat Commun, 15, 2024
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6E7O
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![BU of 6e7o by Molmil](/molmil-images/mine/6e7o) | Crystal structure of deglycosylated human EPDR1 | Descriptor: | Mammalian ependymin-related protein 1 | Authors: | Wei, Y, Prive, G.G. | Deposit date: | 2018-07-27 | Release date: | 2019-01-23 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters. Commun Biol, 2, 2019
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6E8N
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![BU of 6e8n by Molmil](/molmil-images/mine/6e8n) | Crystal structure of glycosylated human EPDR1 | Descriptor: | Mammalian ependymin-related protein 1, NONAETHYLENE GLYCOL | Authors: | Wei, Y, Prive, G.G. | Deposit date: | 2018-07-30 | Release date: | 2019-01-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters. Commun Biol, 2, 2019
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6P6C
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![BU of 6p6c by Molmil](/molmil-images/mine/6p6c) | |
6P6B
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![BU of 6p6b by Molmil](/molmil-images/mine/6p6b) | |
1JKM
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![BU of 1jkm by Molmil](/molmil-images/mine/1jkm) | BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE | Descriptor: | BREFELDIN A ESTERASE | Authors: | Wei, Y, Contreras, A.J, Sheffield, P, Osterlund, T, Derewenda, U, Matern, U.O, Derewenda, Z.S. | Deposit date: | 1998-02-04 | Release date: | 1999-02-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase. Nat.Struct.Biol., 6, 1999
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8WFJ
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![BU of 8wfj by Molmil](/molmil-images/mine/8wfj) | |
8WFL
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![BU of 8wfl by Molmil](/molmil-images/mine/8wfl) | |
8WFI
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![BU of 8wfi by Molmil](/molmil-images/mine/8wfi) | |
8WFK
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![BU of 8wfk by Molmil](/molmil-images/mine/8wfk) | |
1FTN
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![BU of 1ftn by Molmil](/molmil-images/mine/1ftn) | CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12) | Authors: | Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S. | Deposit date: | 1997-03-13 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of RhoA-GDP and its functional implications. Nat.Struct.Biol., 4, 1997
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1P68
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![BU of 1p68 by Molmil](/molmil-images/mine/1p68) | Solution structure of S-824, a de novo designed four helix bundle | Descriptor: | De novo designed protein S-824 | Authors: | Wei, Y, Kim, S, Fela, D, Baum, J, Hecht, M.H. | Deposit date: | 2003-04-29 | Release date: | 2003-11-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a de novo protein from a designed combinatorial library. Proc.Natl.Acad.Sci.Usa, 100, 2003
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1ESC
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![BU of 1esc by Molmil](/molmil-images/mine/1esc) | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | Descriptor: | ESTERASE | Authors: | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | Deposit date: | 1994-10-07 | Release date: | 1995-10-15 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A novel variant of the catalytic triad in the Streptomyces scabies esterase. Nat.Struct.Biol., 2, 1995
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4I8O
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6E16
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![BU of 6e16 by Molmil](/molmil-images/mine/6e16) | Ternary structure of c-Myc-TBP-TAF1 | Descriptor: | Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein | Authors: | Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2018-07-09 | Release date: | 2019-10-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Multiple direct interactions of TBP with the MYC oncoprotein. Nat.Struct.Mol.Biol., 26, 2019
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1JFR
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1F1J
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4EFB
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![BU of 4efb by Molmil](/molmil-images/mine/4efb) | Crystal structure of DNA ligase | Descriptor: | 4-amino-2-(cyclopentyloxy)-6-{[(1R,2S)-2-hydroxycyclopentyl]oxy}pyrimidine-5-carboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ... | Authors: | Wei, Y, Wang, T, Charifson, P, Xu, W. | Deposit date: | 2012-03-29 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of DNA ligase To be Published
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4EFE
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![BU of 4efe by Molmil](/molmil-images/mine/4efe) | crystal structure of DNA ligase | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, SULFATE ION, ... | Authors: | Wei, Y, Wang, T, Charifson, P, Xu, W. | Deposit date: | 2012-03-29 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | crystal structure of DNA ligase To be Published
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1ESE
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![BU of 1ese by Molmil](/molmil-images/mine/1ese) | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | Descriptor: | DIETHYL PHOSPHONATE, ESTERASE | Authors: | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | Deposit date: | 1994-10-07 | Release date: | 1995-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel variant of the catalytic triad in the Streptomyces scabies esterase. Nat.Struct.Biol., 2, 1995
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1ESD
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![BU of 1esd by Molmil](/molmil-images/mine/1esd) | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | Descriptor: | ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP | Authors: | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | Deposit date: | 1994-10-07 | Release date: | 1995-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A novel variant of the catalytic triad in the Streptomyces scabies esterase. Nat.Struct.Biol., 2, 1995
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