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PDB: 12920 件

8DN3
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Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
著者Liu, X, Wang, W.
登録日2022-07-10
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Asymmetric gating of a human hetero-pentameric glycine receptor.
Nat Commun, 14, 2023
2WHV
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CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 (ALL CATION BINDING SITES OCCUPIED BY CALCIUM)
分子名称: CADHERIN-23, CALCIUM ION, CHLORIDE ION, ...
著者Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P.
登録日2009-05-07
公開日2010-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
2WJH
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Structure and function of the FeoB G-domain from Methanococcus jannaschii
分子名称: CITRATE ANION, FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, ...
著者Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O.
登録日2009-05-26
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
6B0D
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An E. coli DPS protein from ferritin superfamily
分子名称: DNA protection during starvation protein, FORMIC ACID, SODIUM ION
著者Rui, W, Ruslan, S, Ronan, K, Adam, J.S.
登録日2017-09-14
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献SIMBAD: a sequence-independent molecular-replacement pipeline.
Acta Crystallogr D Struct Biol, 74, 2018
1J1N
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Structure Analysis of AlgQ2, A Macromolecule(Alginate)-Binding Periplasmic Protein Of Sphingomonas Sp. A1., Complexed with an Alginate Tetrasaccharide
分子名称: AlgQ2, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid
著者Momma, K, Mikami, B, Mishima, Y, Hashimoto, W, Murata, K.
登録日2002-12-11
公開日2003-06-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1, complexed with an alginate tetrasaccharide at 1.6-A resolution
J.BIOL.CHEM., 278, 2003
6M4R
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Structure of Human Serum Albumin
分子名称: Serum albumin
著者Xiang, W, Su, J.
登録日2020-03-09
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure of Human Serum Albumin
To Be Published
6J11
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MERS-CoV spike N-terminal domain and 7D10 scFv complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-terminal domain of Spike glycoprotein, ...
著者Zhou, H, Zhang, S, Zhang, S, Tang, W, Wang, X.
登録日2018-12-27
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein.
Nat Commun, 10, 2019
8EEC
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Crystal structure of HPK1 citron-homology domain
分子名称: Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHATE ION
著者Wu, P, Lehoux, I, Wang, W.
登録日2022-09-06
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献HPK1 Citron Homology Domain Serves as a Scaffold to Promote Phosphorylation of SLP76
To Be Published
6EDL
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hALK in complex with compound 1 (S)-N-(1-(2,4-difluorophenyl)ethyl)-3-(3-methyl-1H-pyrazol-5-yl)imidazo[1,2-b]pyridazin-6-amine
分子名称: ALK tyrosine kinase receptor, N-[(1S)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1H-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine
著者Lane, W, Saikatendu, K.
登録日2018-08-09
公開日2019-05-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors.
J.Med.Chem., 62, 2019
6M73
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Crystal structure of Enterococcus hirae L-lactate oxidase in complex with D-lactate form ligand
分子名称: 1,2-ETHANEDIOL, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Yoshida, H, Hiraka, K, Tsugawa, W, Sode, K.
登録日2020-03-16
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of lactate oxidase from Enterococcus hirae revealed new aspects of active site loop function: Product-inhibition mechanism and oxygen gatekeeper
Protein Sci., 31, 2022
6M74
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Crystal structure of Enterococcus hirae L-lactate oxidase M207L in complex with D-lactate form ligand
分子名称: 1,2-ETHANEDIOL, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Yoshida, H, Hiraka, K, Tsugawa, W, Sode, K.
登録日2020-03-16
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure of lactate oxidase from Enterococcus hirae revealed new aspects of active site loop function: Product-inhibition mechanism and oxygen gatekeeper
Protein Sci., 31, 2022
1J97
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Phospho-Aspartyl Intermediate Analogue of Phosphoserine phosphatase
分子名称: MAGNESIUM ION, PHOSPHATE ION, Phosphoserine Phosphatase
著者Cho, H, Wang, W, Kim, R, Yokota, H, Damo, S, Kim, S.-H, Wemmer, D, Kustu, S, Yan, D, Berkeley Structural Genomics Center (BSGC)
登録日2001-05-24
公開日2001-07-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.
Proc.Natl.Acad.Sci.USA, 98, 2001
1IEH
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SOLUTION STRUCTURE OF A SOLUBLE SINGLE-DOMAIN ANTIBODY WITH HYDROPHOBIC RESIDUES TYPICAL OF A VL/VH INTERFACE
分子名称: BRUC.D4.4
著者Vranken, W, Tolkatchev, D, Xu, P, Tanha, J, Chen, Z, Narang, S, Ni, F.
登録日2001-04-09
公開日2002-08-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of a llama single-domain antibody with hydrophobic residues typical of the VH/VL interface.
Biochemistry, 41, 2002
5J3F
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NMR solution structure of [Rp, Rp]-PT dsDNA
分子名称: DNA (5'-D(*CP*GP*(RSG)P*CP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*(RSG)P*CP*CP*G)-3')
著者Lan, W, Hu, Z, Cao, C.
登録日2016-03-30
公開日2016-11-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation into physiological DNA phosphorothioate modification
Sci Rep, 6, 2016
5C58
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A double mutant of serratia marcescens hemophore receptor HasR in complex with its hemophore HasA and heme
分子名称: HasR protein, Hemophore HasA, PROTOPORPHYRIN IX CONTAINING FE
著者Becker, S, Diederichs, K, Welte, W.
登録日2015-06-19
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献Binding of HasA by its transmembrane receptor HasR follows a conformational funnel mechanism.
Eur.Biophys.J., 49, 2020
8ENA
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Thaumatin native-SAD structure determined at 5 keV with a helium environmet
分子名称: Thaumatin-1
著者Karasawa, A, Andi, B, Ruchs, M.R, Shi, W, McSweeney, S, Hendrickson, W.A, Liu, Q.
登録日2022-09-29
公開日2022-11-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Multi-crystal native-SAD phasing at 5 keV with a helium environment.
Iucrj, 9, 2022
8EN9
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TehA native-SAD structure determined at 5 keV with a helium environment
分子名称: CHLORIDE ION, SODIUM ION, Tellurite resistance protein TehA homolog, ...
著者Karasawa, A, Andi, B, Ruchs, M.R, Shi, W, McSweeney, S, Hendrickson, W.A, Liu, Q.
登録日2022-09-29
公開日2022-11-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Multi-crystal native-SAD phasing at 5 keV with a helium environment.
Iucrj, 9, 2022
8EFO
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PZM21-bound mu-opioid receptor-Gi complex
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
8EW4
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Human Serum Albumin with Cobalt (II) and Myristic Acid - crystal 1
分子名称: COBALT (II) ION, MYRISTIC ACID, Serum albumin
著者Gucwa, M, Cooper, D.R, Unciano, J, Lea, K, Kim, L, Lenkiewicz, J, Starban, I, Stewart, A.J, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-10-21
公開日2022-11-09
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids
Chem Sci, 14, 2023
6LZP
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The solution structure of N-terminal elongated hSNF5 RPT1 domain
分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
著者Lee, W, Han, J, Kim, I, Suh, J.Y.
登録日2020-02-19
公開日2020-12-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction.
Int J Mol Sci, 21, 2020
8EY5
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Human Serum Albumin with Cobalt (II) and Myristic Acid - crystal 3
分子名称: COBALT (II) ION, MYRISTIC ACID, Serum albumin
著者Gucwa, M, Cooper, D.R, Stewart, A.J, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-10-26
公開日2022-11-09
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids
Chem Sci, 14, 2023
8EW7
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Human Serum Albumin with Cobalt (II) and Myristic Acid - crystal 2
分子名称: COBALT (II) ION, MYRISTIC ACID, Serum albumin
著者Gucwa, M, Cooper, D.R, Stewart, A.J, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-10-21
公開日2022-11-09
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids
Chem Sci, 14, 2023
8EFQ
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DAMGO-bound mu-opioid receptor-Gi complex
分子名称: DAMGO, ETHANOLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E.
登録日2022-09-08
公開日2022-11-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
5C5C
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Human metabotropic glutamate receptor 7, extracellular ligand binding domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Dong, A, Dobrovetsky, E, Hutchinson, A, Tempel, W, Edwards, A.M, Bountra, C, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2015-06-19
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.862 Å)
主引用文献Human metabotropic glutamate receptor 7, extracellular ligand binding domain
to be published
6MKS
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Cryo-EM structure of NLRC4-CARD filament
分子名称: Chimera protein of NLR family CARD domain-containing protein 4 and EGFP
著者Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
登録日2018-09-26
公開日2018-11-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018

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