2VWL
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![BU of 2vwl by Molmil](/molmil-images/mine/2vwl) | Aminopyrrolidine Factor Xa inhibitor | Descriptor: | 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3R,5S)-1-{[2-FLUORO-4-(2-OXO-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-5-HYDROXYMETHYL-PYRROLIDIN-3-YL)-AMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Groebke-Zbinden, K, Banner, D.W, Benz, J.M, Blasco, F, Decoret, G, Himber, J, Kuhn, B, Panday, N, Ricklin, F, Risch, P, Schlatter, D, Stahl, M, Unger, R, Haap, W. | Deposit date: | 2008-06-26 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit. Eur.J.Med.Chem., 44, 2009
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2E5R
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![BU of 2e5r by Molmil](/molmil-images/mine/2e5r) | Solution structure of the ZZ domain of Dystrobrevin alpha (Dystrobrevin-alpha) | Descriptor: | Dystrobrevin alpha, ZINC ION | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-22 | Release date: | 2007-06-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the ZZ domain of Dystrobrevin alpha (Dystrobrevin-alpha) To be Published
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1CVI
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![BU of 1cvi by Molmil](/molmil-images/mine/1cvi) | CRYSTAL STRUCTURE OF HUMAN PROSTATIC ACID PHOSPHATASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... | Authors: | Jakob, C.G, Lewinski, K, Kuciel, R, Ostrowski, W, Lebioda, L. | Deposit date: | 1999-08-23 | Release date: | 1999-08-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of human prostatic acid phosphatase . Prostate, 42, 2000
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2E6N
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![BU of 2e6n by Molmil](/molmil-images/mine/2e6n) | Solution structure of the TUDOR domain of Staphylococcal nuclease domain-containing protein 1 | Descriptor: | Staphylococcal nuclease domain-containing protein 1 | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-27 | Release date: | 2007-07-03 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the TUDOR domain of Staphylococcal nuclease domain-containing protein 1 To be Published
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2EPP
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![BU of 2epp by Molmil](/molmil-images/mine/2epp) | Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278 | Descriptor: | POZ-, AT hook-, and zinc finger-containing protein 1, ... | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2008-02-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278 To be Published
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1ASX
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![BU of 1asx by Molmil](/molmil-images/mine/1asx) | APICAL DOMAIN OF THE CHAPERONIN FROM THERMOPLASMA ACIDOPHILUM | Descriptor: | PHOSPHATE ION, THERMOSOME | Authors: | Klumpp, M, Baumeister, W, Essen, L.-O. | Deposit date: | 1997-08-11 | Release date: | 1997-12-03 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the substrate binding domain of the thermosome, an archaeal group II chaperonin. Cell(Cambridge,Mass.), 91, 1997
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2EQY
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![BU of 2eqy by Molmil](/molmil-images/mine/2eqy) | Solution structure of the ARID domain of Jarid1b protein | Descriptor: | Jumonji, AT rich interactive domain 1B | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the ARID domain of Jarid1b protein To be Published
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2E5Q
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![BU of 2e5q by Molmil](/molmil-images/mine/2e5q) | Solution structure of the TUDOR domain of PHD finger protein 19, isoform b [Homo sapiens] | Descriptor: | PHD finger protein 19 | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-22 | Release date: | 2007-06-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the TUDOR domain of PHD finger protein 19,
isoform b [Homo sapiens] To be Published
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2E70
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![BU of 2e70 by Molmil](/molmil-images/mine/2e70) | Solution structure of the fifth KOW motif of human transcription elongation factor SPT5 | Descriptor: | Transcription elongation factor SPT5 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-05 | Release date: | 2007-07-10 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the fifth KOW motif of human transcription elongation factor SPT5 To be Published
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1BMV
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![BU of 1bmv by Molmil](/molmil-images/mine/1bmv) | PROTEIN-RNA INTERACTIONS IN AN ICOSAHEDRAL VIRUS AT 3.0 ANGSTROMS RESOLUTION | Descriptor: | PROTEIN (ICOSAHEDRAL VIRUS - A DOMAIN), PROTEIN (ICOSAHEDRAL VIRUS - B AND C DOMAIN), RNA (5'-R(*GP*GP*UP*CP*AP*AP*AP*AP*UP*GP*C)-3') | Authors: | Chen, Z, Stauffacher, C, Li, Y, Schmidt, T, Bomu, W, Kamer, G, Shanks, M, Lomonossoff, G, Johnson, J.E. | Deposit date: | 1989-10-09 | Release date: | 1989-10-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Protein-RNA interactions in an icosahedral virus at 3.0 A resolution. Science, 245, 1989
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1BQB
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![BU of 1bqb by Molmil](/molmil-images/mine/1bqb) | AUREOLYSIN, STAPHYLOCOCCUS AUREUS METALLOPROTEINASE | Descriptor: | CALCIUM ION, PROTEIN (AUREOLYSIN), ZINC ION | Authors: | Medrano, F.J, Banbula, A, Potempa, J, Travis, J, Bode, W. | Deposit date: | 1998-07-14 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Amino-acid sequence and three-dimensional structure of the Staphylococcus aureus metalloproteinase at 1.72 A resolution. Structure, 6, 1998
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2ECR
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![BU of 2ecr by Molmil](/molmil-images/mine/2ecr) | Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase | Descriptor: | flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase | Authors: | Kim, S.H, Hisano, T, Iwasaki, W, Ebihara, A, Miki, K. | Deposit date: | 2007-02-13 | Release date: | 2008-01-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins, 70, 2008
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2VG2
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![BU of 2vg2 by Molmil](/molmil-images/mine/2vg2) | Rv2361 with IPP | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, DIPHOSPHATE, ... | Authors: | Naismith, J.H, Wang, W, Dong, C. | Deposit date: | 2007-11-07 | Release date: | 2007-11-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
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2VDF
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![BU of 2vdf by Molmil](/molmil-images/mine/2vdf) | Structure of the OpcA adhesion from Neisseria meningitidis determined by crystallization from the cubic mesophase | Descriptor: | N-OCTANE, OUTER MEMBRANE PROTEIN, SULFATE ION | Authors: | Cherezov, V, Liu, W, Derrick, J.P, Luan, B, Aksimentiev, A, Katritch, V, Caffrey, M. | Deposit date: | 2007-10-05 | Release date: | 2007-10-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins, 71, 2008
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2VG3
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![BU of 2vg3 by Molmil](/molmil-images/mine/2vg3) | Rv2361 with citronellyl pyrophosphate | Descriptor: | CHLORIDE ION, GERANYL DIPHOSPHATE, GLYCEROL, ... | Authors: | Naismith, J.H, Wang, W, Dong, C. | Deposit date: | 2007-11-08 | Release date: | 2008-05-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structural basis of chain length control in Rv1086. J. Mol. Biol., 381, 2008
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2V11
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![BU of 2v11 by Molmil](/molmil-images/mine/2v11) | Crystal Structure of Renin with Inhibitor 6 | Descriptor: | (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE, RENIN | Authors: | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | Deposit date: | 2007-05-21 | Release date: | 2007-07-03 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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1C0K
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![BU of 1c0k by Molmil](/molmil-images/mine/1c0k) | CRYSTAL STRUCTURE ANALYSIS OF D-AMINO ACID OXIDASE IN COMPLEX WITH L-LACTATE | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, PROTEIN (D-AMINO ACID OXIDASE) | Authors: | Umhau, S, Molla, G, Diederichs, K, Pilone, M.S, Ghisla, S, Welte, W, Pollegioni, L. | Deposit date: | 1999-07-16 | Release date: | 2000-11-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation. Proc.Natl.Acad.Sci.USA, 97, 2000
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2V6V
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![BU of 2v6v by Molmil](/molmil-images/mine/2v6v) | The structure of the Bem1p PX domain | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BUD EMERGENCE PROTEIN 1 | Authors: | Stahelin, R.V, Karathanassis, D, Murray, D, Williams, R.L, Cho, W. | Deposit date: | 2007-07-21 | Release date: | 2007-07-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Membrane Binding Analysis of the Phox Homology Domain of Bem1P: Basis of Phosphatidylinositol 4-Phosphate Specificity. J.Biol.Chem., 282, 2007
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2WPA
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![BU of 2wpa by Molmil](/molmil-images/mine/2wpa) | Optimisation of 6,6-Dimethyl Pyrrolo 3,4-c pyrazoles: Identification of PHA-793887, a Potent CDK Inhibitor Suitable for Intravenous Dosing | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, N-{6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1,4,5,6-TETRAHYDROPYRROLO[3,4-C]PYRAZOL-3-YL}-3-METHYLBUTANAMIDE, ... | Authors: | Brasca, M.G, Albanese, C, Alzani, R, Amici, R, Avanzi, N, Ballinari, D, Bischoff, J, Borghi, D, Casale, E, Croci, V, Fiorentini, F, Isacchi, A, Mercurio, C, Nesi, M, Orsini, P, Pastori, W, Pesenti, E, Pevarello, P, Roussel, P, Varasi, M, Volpi, D, Vulpetti, A, Ciomei, M. | Deposit date: | 2009-08-03 | Release date: | 2010-02-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Optimization of 6,6-Dimethyl Pyrrolo[3,4-C]Pyrazoles: Identification of Pha-793887, a Potent Cdk Inhibitor Suitable for Intravenous Dosing. Bioorg.Med.Chem., 18, 2010
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2BU8
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![BU of 2bu8 by Molmil](/molmil-images/mine/2bu8) | crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DICHLORO-ACETIC ACID, MAGNESIUM ION, ... | Authors: | Knoechel, T.R, Tucker, A.D, Robinson, C.M, Phillips, C, Taylor, W, Bungay, P.J, Kasten, S.A, Roche, T.E, Brown, D.G. | Deposit date: | 2005-06-08 | Release date: | 2006-02-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands. Biochemistry, 45, 2006
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1BV8
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![BU of 1bv8 by Molmil](/molmil-images/mine/1bv8) | |
1BPR
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![BU of 1bpr by Molmil](/molmil-images/mine/1bpr) | NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE | Descriptor: | DNAK | Authors: | Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P. | Deposit date: | 1998-08-11 | Release date: | 1999-03-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction. Biochemistry, 37, 1998
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2BNW
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![BU of 2bnw by Molmil](/molmil-images/mine/2bnw) | Structural basis for cooperative binding of Ribbon-Helix-Helix Omega repressor to direct DNA heptad repeats | Descriptor: | 5'-D(*CP*TP*TP*GP*TP*GP*AP*TP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*AP *TP*CP*AP*CP*AP*AP*GP*C)-3', ORF OMEGA | Authors: | Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. | Deposit date: | 2005-04-05 | Release date: | 2006-03-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription. Nucleic Acids Res., 34, 2006
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2WVN
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![BU of 2wvn by Molmil](/molmil-images/mine/2wvn) | Structure of the HET-s N-terminal domain | Descriptor: | SMALL S PROTEIN | Authors: | Greenwald, J, Buhtz, C, Ritter, C, Kwiatkowski, W, Choe, S, Saupe, S.J, Riek, R. | Deposit date: | 2009-10-19 | Release date: | 2010-07-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | The Mechanism of Prion Inhibition by Het-S. Mol.Cell, 38, 2010
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1C6O
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![BU of 1c6o by Molmil](/molmil-images/mine/1c6o) | CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C6 FROM THE GREEN ALGAE SCENEDESMUS OBLIQUUS | Descriptor: | CYTOCHROME C6, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Schnackenberg, J, Than, M.E, Mann, K, Wiegand, G, Huber, R, Reuter, W. | Deposit date: | 1999-04-07 | Release date: | 2000-04-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Amino acid sequence, crystallization and structure determination of reduced and oxidized cytochrome c6 from the green alga Scenedesmus obliquus. J.Mol.Biol., 290, 1999
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