7TPS
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![BU of 7tps by Molmil](/molmil-images/mine/7tps) | Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Demonte, D.W, Maurer, M.F, Akutsu, M, Kimbung, Y.R, Logan, D.T, Walse, B. | Deposit date: | 2022-01-26 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity. Nat Commun, 13, 2022
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8AB9
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![BU of 8ab9 by Molmil](/molmil-images/mine/8ab9) | Complex III2 from Yarrowia lipolytica, ascorbate-reduced, b-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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2J6Z
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![BU of 2j6z by Molmil](/molmil-images/mine/2j6z) | Structural and functional characterisation of partner-switching regulating the environmental stress response in B. subtilis | Descriptor: | PHOSPHOSERINE PHOSPHATASE RSBU | Authors: | Hardwick, S.W, Pane-Farre, J, Delumeau, O, Marles-Wright, J, Murray, J.W, Hecker, M, Lewis, R.J. | Deposit date: | 2006-10-05 | Release date: | 2007-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis. J. Biol. Chem., 282, 2007
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8AB6
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![BU of 8ab6 by Molmil](/molmil-images/mine/8ab6) | Complex III2 from Yarrowia lipolytica, combined datasets, consensus refinement | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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2J5C
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![BU of 2j5c by Molmil](/molmil-images/mine/2j5c) | Rational conversion of substrate and product specificity in a monoterpene synthase. Structural insights into the molecular basis of rapid evolution. | Descriptor: | 1,8-CINEOLE SYNTHASE, BETA-MERCAPTOETHANOL | Authors: | Kampranis, S.C, Ioannidis, D, Purvis, A, Mahrez, W, Ninga, E, Katerelos, N.A, Anssour, S, Dunwell, J.M, Makris, A.M, Goodenough, P.W, Johnson, C.B. | Deposit date: | 2006-09-14 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights Into the Evolution of Terpene Synthase Function. Plant Cell, 19, 2007
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8ABM
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![BU of 8abm by Molmil](/molmil-images/mine/8abm) | Complex III2 from Yarrowia lipolytica, apo, b-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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6PF9
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![BU of 6pf9 by Molmil](/molmil-images/mine/6pf9) | Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)phenyl)acetic acid. | Descriptor: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, METHOTREXATE, ... | Authors: | Czyzyk, D.J, Valhondo, M, Jorgensen, W.L, Anderson, K.S. | Deposit date: | 2019-06-21 | Release date: | 2019-10-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
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8AB7
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![BU of 8ab7 by Molmil](/molmil-images/mine/8ab7) | Complex III2 from Yarrowia lipolytica, atovaquone and antimycin A bound | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8ABB
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![BU of 8abb by Molmil](/molmil-images/mine/8abb) | Complex III2 from Yarrowia lipolytica, ascorbate-reduced, c-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8ABA
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![BU of 8aba by Molmil](/molmil-images/mine/8aba) | Complex III2 from Yarrowia lipolytica, ascorbate-reduced, int-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8ABJ
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![BU of 8abj by Molmil](/molmil-images/mine/8abj) | Complex III2 from Yarrowia lipolytica, antimycin A bound, c-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8ABH
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![BU of 8abh by Molmil](/molmil-images/mine/8abh) | Complex III2 from Yarrowia lipolytica, antimycin A bound, b-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8AC4
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![BU of 8ac4 by Molmil](/molmil-images/mine/8ac4) | Complex III2 from Yarrowia lipolytica, apo, c-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-05 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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3W96
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![BU of 3w96 by Molmil](/molmil-images/mine/3w96) | Crystal Structure of Human Nucleosome Core Particle lacking H2A N-terminal region | Descriptor: | 146-mer DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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8ABF
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![BU of 8abf by Molmil](/molmil-images/mine/8abf) | Complex III2 from Yarrowia lipolytica, oxidised with ferricyanide, int-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8ABK
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![BU of 8abk by Molmil](/molmil-images/mine/8abk) | Complex III2 from Yarrowia lipolytica, decylubiquinol bound, b-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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3WAA
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![BU of 3waa by Molmil](/molmil-images/mine/3waa) | The nucleosome containing human H2A.Z.2 | Descriptor: | DNA (146-MER), Histone H2A.V, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | Deposit date: | 2013-04-30 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2 Acta Crystallogr.,Sect.D, 69, 2013
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8ABE
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![BU of 8abe by Molmil](/molmil-images/mine/8abe) | Complex III2 from Yarrowia lipolytica, oxidised with ferricyanide, b-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8ABG
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![BU of 8abg by Molmil](/molmil-images/mine/8abg) | Complex III2 from Yarrowia lipolytica, oxidised with ferricyanide, c-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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8AC3
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![BU of 8ac3 by Molmil](/molmil-images/mine/8ac3) | Complex III2 from Yarrowia lipolytica, apo, int-position | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-05 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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2XLP
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![BU of 2xlp by Molmil](/molmil-images/mine/2xlp) | Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: Asn78Ser mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Orru, R, Fraaije, M.W, Mattevi, A. | Deposit date: | 2010-07-21 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Joint functions of protein residues and NADP(H) in oxygen activation by flavin-containing monooxygenase. J. Biol. Chem., 285, 2010
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1APX
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![BU of 1apx by Molmil](/molmil-images/mine/1apx) | |
8AB8
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![BU of 8ab8 by Molmil](/molmil-images/mine/8ab8) | Complex III2, b-position, with decylubiquinone and ascorbate-reduced | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | Authors: | Wieferig, J.P, Kuhlbrandt, W. | Deposit date: | 2022-07-04 | Release date: | 2023-01-11 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM. Iucrj, 10, 2023
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4XW6
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![BU of 4xw6 by Molmil](/molmil-images/mine/4xw6) | X-ray structure of PKAc with ADP, free phosphate ion, CP20, magnesium ions | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Gerlits, O, Tian, J, Das, A, Taylor, S, Langan, P, Heller, T.W, Kovalevsky, A. | Deposit date: | 2015-01-28 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Phosphoryl Transfer Reaction Snapshots in Crystals: INSIGHTS INTO THE MECHANISM OF PROTEIN KINASE A CATALYTIC SUBUNIT. J.Biol.Chem., 290, 2015
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6PBJ
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![BU of 6pbj by Molmil](/molmil-images/mine/6pbj) | The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase with Gly190Pro mutation | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Jiao, W, Fan, Y, Blackmore, N.J, Parker, E.J. | Deposit date: | 2019-06-13 | Release date: | 2020-04-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis . J.Biol.Chem., 295, 2020
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