8CN0
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![BU of 8cn0 by Molmil](/molmil-images/mine/8cn0) | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-21 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A To Be Published
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7MX6
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![BU of 7mx6 by Molmil](/molmil-images/mine/7mx6) | Leishmania major dihydroorotate dehydrogenase in complex with [4-(1H-pyrrol-1-yl)phenyl]methanol | 分子名称: | 4-(1H-pyrrol-1-yl)aniline, Dihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, ... | 著者 | Pinheiro, M.P, Hunter, W.N, Cardoso, I.A, Nonato, M.C. | 登録日 | 2021-05-18 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Leishmania major dihydroorotate dehydrogenase in complex with [4-(1H-pyrrol-1-yl)phenyl]methanol To be Published
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8CNB
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![BU of 8cnb by Molmil](/molmil-images/mine/8cnb) | Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | 主引用文献 | Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A To Be Published
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8CNA
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![BU of 8cna by Molmil](/molmil-images/mine/8cna) | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | 分子名称: | ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.463 Å) | 主引用文献 | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA To Be Published
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8CMZ
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![BU of 8cmz by Molmil](/molmil-images/mine/8cmz) | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-21 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.252 Å) | 主引用文献 | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A To Be Published
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8CND
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![BU of 8cnd by Molmil](/molmil-images/mine/8cnd) | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | 分子名称: | ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.972 Å) | 主引用文献 | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA To Be Published
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7MYD
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![BU of 7myd by Molmil](/molmil-images/mine/7myd) | Leishmania major dihydroorotate dehydrogenase in complex with 5-amino-2-(1H-pyrrol-1-yl)benzonitrile | 分子名称: | 5-azanyl-2-pyrrol-1-yl-benzenecarbonitrile, Dihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, ... | 著者 | Pinheiro, M.P, Cardoso, I.A, Hunter, W.N, Nonato, M.C. | 登録日 | 2021-05-20 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Leishmania major dihydroorotate dehydrogenase in complex with 5-amino-2-(1H-pyrrol-1-yl)benzonitrile To Be Published
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6YGV
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![BU of 6ygv by Molmil](/molmil-images/mine/6ygv) | tRNA-Guanine Transglycosylase (TGT) in co-crystallized complex with (E)-N-ethyl-4-oxo-4-phenylbut-2-enamide | 分子名称: | GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION, ... | 著者 | Nguyen, A, Heyder, L, Heine, A, Diederich, W, Klebe, G. | 登録日 | 2020-03-27 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Ligands disturb dimer contacts To Be Published
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6YJ6
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![BU of 6yj6 by Molmil](/molmil-images/mine/6yj6) | Structure of the TFIIIC subcomplex tauA | 分子名称: | Transcription factor tau 131 kDa subunit, Transcription factor tau 55 kDa subunit, Transcription factor tau 95 kDa subunit,Transcription factor tau 95 kDa subunit | 著者 | Vorlaender, M.K, Muller, C.W. | 登録日 | 2020-04-02 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the TFIIIC subcomplex tau A provides insights into RNA polymerase III pre-initiation complex formation. Nat Commun, 11, 2020
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7DVN
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![BU of 7dvn by Molmil](/molmil-images/mine/7dvn) | Crystal structure of a MarR family protein in complex with a lipid-like effector molecule from the psychrophilic bacterium Paenisporosarcina sp. TG-14 | 分子名称: | MarR family transcriptional regulator, PALMITIC ACID | 著者 | Lee, C.W, Hwang, J, Do, H, Lee, J.H. | 登録日 | 2021-01-14 | 公開日 | 2021-11-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a MarR family protein from the psychrophilic bacterium Paenisporosarcina sp. TG-14 in complex with a lipid-like molecule. Iucrj, 8, 2021
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2M5N
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![BU of 2m5n by Molmil](/molmil-images/mine/2m5n) | Atomic-resolution structure of a cross-beta protofilament | 分子名称: | Transthyretin | 著者 | Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M. | 登録日 | 2013-02-27 | 公開日 | 2013-07-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril. Proc.Natl.Acad.Sci.USA, 110, 2013
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8C67
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![BU of 8c67 by Molmil](/molmil-images/mine/8c67) | Crystal structure of Ab25 Fab | 分子名称: | antibody 25 heavy chain, antibody 25 light chain | 著者 | Nyblom, M, Izadi, A, Tang, D, Bahnan, W, Happonen, L, Malmstroem, J, Shannon, O, Malmstroem, L, Nordenfelt, P. | 登録日 | 2023-01-11 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Engineering of IgG1 hinge to the flexible IgG3 hinge enhances immune defense against streptococci To Be Published
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7N47
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![BU of 7n47 by Molmil](/molmil-images/mine/7n47) | The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988514 | 分子名称: | 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... | 著者 | Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. | 登録日 | 2021-06-03 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
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7N55
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![BU of 7n55 by Molmil](/molmil-images/mine/7n55) | The crystal structure of the mutant I38T PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988514 | 分子名称: | 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... | 著者 | Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. | 登録日 | 2021-06-04 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
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7N8F
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![BU of 7n8f by Molmil](/molmil-images/mine/7n8f) | The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988288 | 分子名称: | Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, Polymerase acidic protein, ... | 著者 | Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. | 登録日 | 2021-06-14 | 公開日 | 2022-06-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
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2ME2
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![BU of 2me2 by Molmil](/molmil-images/mine/2me2) | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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7N8U
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![BU of 7n8u by Molmil](/molmil-images/mine/7n8u) | |
8IAN
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![BU of 8ian by Molmil](/molmil-images/mine/8ian) | Crystal structure of CtPL-H210S/F214I mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PET hydrolase | 著者 | Li, X, Shi, B.L, Zeng, Z.Y, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-02-08 | 公開日 | 2023-04-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Functional tailoring of a PET hydrolytic enzyme expressed in Pichia pastoris. Bioresour Bioprocess, 10, 2023
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8IQU
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![BU of 8iqu by Molmil](/molmil-images/mine/8iqu) | Structure of MtbFadD23 with PhU-AMS | 分子名称: | 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, Fatty-acid-CoA ligase FadD23 | 著者 | Yan, M.R, Zhang, W. | 登録日 | 2023-03-17 | 公開日 | 2023-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis for the development of potential inhibitors targeting FadD23 from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.F, 79, 2023
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1RCT
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![BU of 1rct by Molmil](/molmil-images/mine/1rct) | Crystal structure of Human purine nucleoside phosphorylase complexed with INOSINE | 分子名称: | INOSINE, Purine nucleoside phosphorylase, SULFATE ION | 著者 | Canduri, F, dos Santos, D.M, Silva, R.G, Mendes, M.A, Palma, M.S, de Azevedo Jr, W.F, Basso, L.A, Santos, D.S. | 登録日 | 2003-11-04 | 公開日 | 2004-01-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of human purine nucleoside phosphorylase complexed with inosine and ddI Biochem.Biophys.Res.Commun., 313, 2004
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7MZO
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![BU of 7mzo by Molmil](/molmil-images/mine/7mzo) | Crystal structure of the UcaD lectin-binding domain | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | 登録日 | 2021-05-24 | 公開日 | 2022-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. Plos Pathog., 18, 2022
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7MZQ
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![BU of 7mzq by Molmil](/molmil-images/mine/7mzq) | Crystal structure of the UcaD lectin-binding domain in complex with fucose | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD, beta-L-fucopyranose | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | 登録日 | 2021-05-24 | 公開日 | 2022-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. Plos Pathog., 18, 2022
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7N9O
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![BU of 7n9o by Molmil](/molmil-images/mine/7n9o) | Estrogen Receptor Alpha Ligand Binding Domain in Complex with Aliphatic SERD S-C10(15) | 分子名称: | 10-{[3,17beta-dihydroxyestra-1,3,5(10)-trien-7beta-yl]sulfanyl}-N-methyl-N-propyldecanamide, Estrogen receptor | 著者 | Diennet, M, El Ezzy, M, Thiombane, K, Cotnoir-White, D, Poupart, J, Gao, Z, Mendoza, S.R, Marinier, A, Gleason, J, Mader, S.C, Fanning, S.W. | 登録日 | 2021-06-18 | 公開日 | 2022-07-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Estrogen Receptor Alpha Ligand Binding Domain in Complex with Aliphatic SERD S-C10(15) To Be Published
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7MZS
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![BU of 7mzs by Molmil](/molmil-images/mine/7mzs) | Crystal structure of the UcaD lectin-binding domain in complex with galactose | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD, alpha-D-galactopyranose | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | 登録日 | 2021-05-24 | 公開日 | 2022-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli. Plos Pathog., 18, 2022
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4QKO
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![BU of 4qko by Molmil](/molmil-images/mine/4qko) | The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms | 分子名称: | BROMIDE ION, MAGNESIUM ION, Pyocin-S2, ... | 著者 | Grinter, R, Josts, I, Roszak, A.W, Cogdell, C.J, Walker, D. | 登録日 | 2014-06-07 | 公開日 | 2015-06-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights into pyocin S2 To be Published
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