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PDB: 109 件
2FEY
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BU of 2fey by Molmil
The structure of stem loop IV of Tetrahymena telomerase RNA
分子名称: stem-loop IV of Tetrahymena telomerase RNA
著者Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G.
登録日2005-12-16
公開日2006-06-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of stem-loop IV of Tetrahymena telomerase RNA.
Embo J., 25, 2006
1ARJ
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BU of 1arj by Molmil
ARG-BOUND TAR RNA, NMR
分子名称: ARGININE, TAR RNA
著者Aboul-Ela, F, Varani, G, Karn, J.
登録日1995-08-30
公開日1996-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.
J.Mol.Biol., 253, 1995
1UUI
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NMR structure of a synthetic small molecule, rbt158, bound to HIV-1 TAR RNA
分子名称: 4-[AMINO(IMINO)METHYL]-1-[2-(3-AMMONIOPROPOXY)-5-METHOXYBENZYL]PIPERAZIN-1-IUM, 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP* CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C)-3'
著者Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F.
登録日2003-12-19
公開日2004-02-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
1UUD
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NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA
分子名称: N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3')
著者Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F.
登録日2003-12-18
公開日2004-03-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
2KX5
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BU of 2kx5 by Molmil
Recognition of HIV TAR RNA by peptide mimetic of Tat protein
分子名称: Cyclic peptide mimetic of Tat protein, HIV TAR RNA
著者Davidson, A, Patora-Komisarska, K, Robinson, J, Varani, G.
登録日2010-04-26
公開日2010-07-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein.
Nucleic Acids Res., 39, 2011
2KM8
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BU of 2km8 by Molmil
Interdomain RRM packing contributes to RNA recognition in the rna15, hrp1, anchor RNA 3' processing ternary complex
分子名称: 5'-R(P*UP*AP*UP*AP*UP*AP*UP*AP*AP*UP*AP*AP*U)-3', Nuclear polyadenylated RNA-binding protein 4, mRNA 3'-end-processing protein RNA15
著者Leeper, T.C, Varani, G.
登録日2009-07-24
公開日2010-07-28
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Novel Protein-Protein Contacts Facilitate mRNA 3'-Processing Signal Recognition by Rna15 and Hrp1.
J.Mol.Biol., 401, 2010
2L2S
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BU of 2l2s by Molmil
Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine
分子名称: 1-{[(4-methylphenyl)sulfanyl]acetyl}piperidine, Peptidyl-prolyl cis-trans isomerase
著者Zheng, S, Barnwal, R, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-27
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine
To be Published
2L8H
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BU of 2l8h by Molmil
Chemical probe bound to HIV TAR RNA
分子名称: 4-methoxynaphthalen-2-amine, ARGININE, HIV TAR RNA
著者Davidson, A, Begley, D, Lau, C, Varani, G.
登録日2011-01-12
公開日2011-03-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Small-Molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-Like Fragments.
J.Mol.Biol., 410, 2011
2L0I
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BU of 2l0i by Molmil
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide
分子名称: DNA-directed RNA polymerase, Regulator of Ty1 transposition protein 103
著者Lunde, B.M, Reichow, S.L, Kim, M, Suh, H, Leeper, T.C, Yang, F, Mutschler, H, Buratowski, S, Meinhart, A, Varani, G.
登録日2010-07-06
公開日2010-09-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
2LOL
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NMR structure of an acyl-carrier protein from Rickettsia prowazekii, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
分子名称: Acyl carrier protein
著者Barnwal, R, Gonen, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-01-25
公開日2012-02-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of an acyl-carrier protein from Rickettsia prowazekii, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
To be Published
2L2Q
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Solution Structure of cellobiose-specific phosphotransferase IIB component protein from Borrelia burgdorferi
分子名称: PTS system, cellobiose-specific IIB component (CelA)
著者Yang, F, Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-08-25
公開日2010-09-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of cellobiose-specific phosphotransferase IIB component protein from Borrelia burgdorferi
To be Published
2LHJ
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BU of 2lhj by Molmil
NMR structure of the high mobility group protein-like protein NHP1 from Babesia bovis T2Bo (BaboA.00841.a)
分子名称: High mobility group protein homolog NHP1
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-11
公開日2011-08-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H and 15N Assigned Chemical Shifts for high mobility group protein-like protein NHP1 from Babesia bovis
To be Published
2LBB
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Solution structure of acyl CoA binding protein from Babesia bovis T2Bo
分子名称: Acyl CoA binding protein
著者Yang, F, Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-03-29
公開日2011-04-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of acyl CoA binding protein from Babesia bovis T2Bo
To be Published
1Z31
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BU of 1z31 by Molmil
The structure of an enzyme-activating fragment of human telomerase RNA
分子名称: human telomerase PJ6 hairpin
著者Leeper, T.C, Varani, G.
登録日2005-03-10
公開日2005-03-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of an enzyme-activating fragment of human telomerase RNA.
RNA, 11, 2005
2A9X
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BU of 2a9x by Molmil
TAR RNA recognition by a cyclic peptidomimetic of Tat protein
分子名称: BIV TAR RNA, BIV-2 cyclic peptide
著者Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G.
登録日2005-07-12
公開日2005-11-01
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry, 44, 2005
5T3Y
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BU of 5t3y by Molmil
Solution structure of response regulator protein from Burkholderia multivorans
分子名称: Two-component system response regulator
著者Yang, F, Lim, Y.-B, Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2016-08-26
公開日2016-09-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of response regulator protein from Burkholderia multivorans
To Be Published
2AQC
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BU of 2aqc by Molmil
NMR Structural analysis of archaeal Nop10
分子名称: Ribosome biogenesis protein Nop10, ZINC ION
著者Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
登録日2005-08-17
公開日2005-11-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
2AQA
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BU of 2aqa by Molmil
NMR structural analysis of Nop10p from Saccharomyces cerevisiae
分子名称: H/ACA ribonucleoprotein complex subunit 3
著者Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
登録日2005-08-17
公開日2005-11-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
5UZZ
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BU of 5uzz by Molmil
Structure of wild type pre-miR21 apical loop
分子名称: 14-mer Peptide, pre-miR21
著者Shortridge, M.D, Varani, G.
登録日2017-02-27
公開日2017-06-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol., 12, 2017
1IKD
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BU of 1ikd by Molmil
ACCEPTOR STEM, NMR, 30 STRUCTURES
分子名称: TRNA ALA ACCEPTOR STEM
著者Ramos, A, Varani, G.
登録日1996-11-15
公開日1997-04-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the acceptor stem of Escherichia coli tRNA Ala: role of the G3.U70 base pair in synthetase recognition.
Nucleic Acids Res., 25, 1997
1KP7
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BU of 1kp7 by Molmil
Conserved RNA Structure within the HCV IRES eIF3 Binding Site
分子名称: Hepatitis C Virus Internal Ribosome Entry Site Fragment
著者Gallego, J, Klinck, R, Collier, A.J, Cole, P.T, Harris, S.J, Harrison, G.P, Aboul-ela, F, Walker, S, Varani, G.
登録日2001-12-29
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A conserved RNA structure within the HCV IRES eIF3-binding site.
Nat.Struct.Biol., 9, 2002
5J0M
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BU of 5j0m by Molmil
Ground state sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
分子名称: Apical region (29-mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat
著者Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M.
登録日2016-03-28
公開日2016-06-08
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J1O
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Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
分子名称: Apical region (29mer) of the HIV-1 TAR element, Cyclic peptide mimetic of Tat
著者Borkar, A.N, Bardaro, M.F, Varani, G, Vendruscolo, M.
登録日2016-03-29
公開日2016-06-08
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
2APO
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Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
分子名称: POTASSIUM ION, Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ...
著者Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
登録日2005-08-16
公開日2005-11-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
5J2W
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Intermediate state lying on the pathway of release of Tat from HIV-1 TAR.
分子名称: Apical region (29mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat
著者Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M.
登録日2016-03-30
公開日2016-06-08
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016

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