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PDB: 33 件
2R0Y
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BU of 2r0y by Molmil
Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide
分子名称: Chromatin structure-remodeling complex protein RSC4, Histone H3 peptide
著者VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R.
登録日2007-08-21
公開日2007-10-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
5VFZ
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BU of 5vfz by Molmil
Integrase from mycobacterium phage Brujita
分子名称: ACETATE ION, GLYCEROL, Gp33, ...
著者VanDemark, A.P, Lunt, B, Hatfull, G.F.
登録日2017-04-10
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.847 Å)
主引用文献Integrase from mycobacterium phage Brujita
To Be Published
7RDE
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BU of 7rde by Molmil
Human Triose Phosphate Isomerase Q181P
分子名称: BROMIDE ION, CALCIUM ION, Triosephosphate isomerase
著者VanDemark, A.P, Kowalski, J.
登録日2021-07-09
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency.
Dis Model Mech, 15, 2022
1JAT
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BU of 1jat by Molmil
Mms2/Ubc13 Ubiquitin Conjugating Enzyme Complex
分子名称: Ubiquitin-Conjugating Enzyme E2-17.5 KDA, Ubiquitin-Conjugating Enzyme Variant Mms2
著者VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C.
登録日2001-05-31
公開日2001-06-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
1JBB
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BU of 1jbb by Molmil
Ubiquitin Conjugating Enzyme, Ubc13
分子名称: ubiquitin conjugating enzyme E2-17.5 KDA
著者VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C.
登録日2001-06-03
公開日2001-06-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
Cell(Cambridge,Mass.), 105, 2001
3BIP
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BU of 3bip by Molmil
Crystal structure of yeast Spt16 N-terminal Domain
分子名称: FACT complex subunit SPT16
著者VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T.
登録日2007-11-30
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
J.Biol.Chem., 283, 2008
3BIT
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BU of 3bit by Molmil
Crystal structure of yeast Spt16 N-terminal Domain
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, FACT complex subunit SPT16, ...
著者VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T.
登録日2007-11-30
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
J.Biol.Chem., 283, 2008
3BIQ
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BU of 3biq by Molmil
Crystal structure of yeast Spt16 N-terminal Domain
分子名称: FACT complex subunit SPT16, GLYCEROL
著者VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T.
登録日2007-11-30
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
J.Biol.Chem., 283, 2008
2GCJ
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BU of 2gcj by Molmil
Crystal Structure of the Pob3 middle domain
分子名称: Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region
著者VanDemark, A.P.
登録日2006-03-14
公開日2006-05-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition.
Mol.Cell, 22, 2006
2GCL
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BU of 2gcl by Molmil
Structure of the Pob3 Middle domain
分子名称: CHLORIDE ION, Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region
著者VanDemark, A.P.
登録日2006-03-14
公開日2006-05-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition.
Mol.Cell, 22, 2006
2R10
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BU of 2r10 by Molmil
Structure of an acetylated Rsc4 tandem bromodomain Histone Chimera
分子名称: 1,2-ETHANEDIOL, Chromatin structure-remodeling complex protein RSC4, LINKER, ...
著者VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R.
登録日2007-08-21
公開日2007-10-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
2R0S
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BU of 2r0s by Molmil
Crystal Structure of the Rsc4 tandem bromodomain
分子名称: Chromatin structure-remodeling complex protein RSC4
著者VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R.
登録日2007-08-21
公開日2007-10-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
2R3C
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BU of 2r3c by Molmil
Structure of the gp41 N-peptide in complex with the HIV entry inhibitor PIE1
分子名称: CHLORIDE ION, HIV entry inhibitor PIE1, YTTRIUM (III) ION, ...
著者VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S.
登録日2007-08-29
公開日2007-10-02
最終更新日2018-08-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R0V
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BU of 2r0v by Molmil
Structure of the Rsc4 tandem bromodomain acetylated at K25
分子名称: Chromatin structure-remodeling complex protein RSC4, SULFATE ION
著者VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R.
登録日2007-08-21
公開日2007-10-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
2R5B
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BU of 2r5b by Molmil
Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7
分子名称: HIV entry inhibitor PIE7, SULFATE ION, gp41 N-peptide
著者VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S.
登録日2007-09-03
公開日2007-10-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R5D
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BU of 2r5d by Molmil
Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HIV entry inhibitor PIE7, ...
著者VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S.
登録日2007-09-03
公開日2007-10-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
8EXZ
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BU of 8exz by Molmil
Structure of GDAP1 containing CMT mutant T157P
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Googins, M.R, VanDemark, A.P.
登録日2022-10-26
公開日2023-11-08
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structure of GDAP1 containing CMT mutant T157P
To Be Published
6UIH
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BU of 6uih by Molmil
Crystal structure of the core domain from the GST-like protein GDAP1
分子名称: Ganglioside-induced differentiation-associated protein 1
著者Googins, M.R, VanDemark, A.P.
登録日2019-09-30
公開日2020-04-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.826 Å)
主引用文献Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily.
Faseb J., 34, 2020
4ZVJ
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BU of 4zvj by Molmil
Structure of human triose phosphate isomerase K13M
分子名称: POTASSIUM ION, SODIUM ION, Triosephosphate isomerase
著者Amrich, C.G, Smith, C, Heroux, A, VanDemark, A.P.
登録日2015-05-18
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6996 Å)
主引用文献Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim. Biophys. Acta, 1852, 2015
6NLH
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BU of 6nlh by Molmil
Structure of human triose phosphate isomerase R189A
分子名称: BROMIDE ION, PHOSPHATE ION, SODIUM ION, ...
著者Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P.
登録日2019-01-08
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
3THF
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BU of 3thf by Molmil
Crystal structure of the SD2 domain from Drosophila Shroom
分子名称: Protein Shroom
著者Mohan, S, VanDemark, A.P.
登録日2011-08-18
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6951 Å)
主引用文献Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction.
Mol Biol Cell, 23, 2012
3V46
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BU of 3v46 by Molmil
Crystal Structure of Yeast Cdc73 C-Terminal Domain
分子名称: Cell division control protein 73
著者Amrich, C.G, VanDemark, A.P.
登録日2011-12-14
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012
5E8B
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BU of 5e8b by Molmil
Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R126A
分子名称: BENZAMIDINE, RNA polymerase-associated protein RTF1, SODIUM ION
著者Wier, A.D, Heroux, A, VanDemark, A.P.
登録日2015-10-14
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol. Cell, 64, 2016
4POD
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BU of 4pod by Molmil
Structure of Triosephosphate Isomerase I170V mutant human enzyme.
分子名称: BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ...
著者Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P.
登録日2014-02-25
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
5EMX
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BU of 5emx by Molmil
Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R124A R126A R128A
分子名称: RNA polymerase-associated protein RTF1
著者Wier, A.D, Heroux, A, VanDemark, A.P.
登録日2015-11-06
公開日2016-10-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol.Cell, 64, 2016

 

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