4P76
| Cellular response to a crystal-forming protein | Descriptor: | Photoconvertible fluorescent protein, SODIUM ION | Authors: | Tsutsui, H, Jinno, Y, Shoda, K, Tomita, A, Matsuda, M, Yamashita, E, Katayama, H, Nakagawa, A, Miyawaki, A. | Deposit date: | 2014-03-26 | Release date: | 2015-04-29 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A diffraction-quality protein crystal processed as an autophagic cargo Mol.Cell, 58, 2015
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1XSS
| Semi-rational engineering of a green-emitting coral fluorescent protein into an efficient highlighter. | Descriptor: | MAGNESIUM ION, SODIUM ION, fluorescent protein | Authors: | Tsutsui, H, Karasawa, S, Shimizu, H, Nukina, N, Miyawaki, A. | Deposit date: | 2004-10-20 | Release date: | 2005-03-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Semi-rational engineering of a coral fluorescent protein into an efficient highlighter Embo Rep., 6, 2005
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6DCG
| Discovery of MK-8353: An Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology | Descriptor: | (3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)-N-(3-{6-[(propan-2-yl)oxy]pyridin-3-yl}-1H-indazol-5-yl)pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | Authors: | Boga, S.B, Deng, Y, Zhu, L, Nan, Y, Cooper, A, Shipps Jr, G.W, Doll, R, Shih, N, Zhu, H, Sun, R, Wang, T, Paliwal, S, Tsui, H, Gao, X, Yao, X, Desai, J, Wang, J, Alhassan, A.B, Kelly, J, Patel, M, Muppalla, K, Gudipati, S, Zhang, L, Buevich, A, Hesk, D, Carr, D, Dayananth, P, Mei, H, Cox, K, Sherborne, B, Hruza, A.W, Xiao, L, Jin, W, Long, B, Liu, G, Taylor, S.A, Kirschmeier, P, Windsor, W.T, Bishop, R, Samatar, A.A. | Deposit date: | 2018-05-06 | Release date: | 2018-08-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology. ACS Med Chem Lett, 9, 2018
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2DDD
| Unique behavior of a histidine responsible for an engineered green-to-red photoconversion process | Descriptor: | MAGNESIUM ION, SODIUM ION, photoconvertible fluorescent protein | Authors: | Shimizu, H, Tsutsui, H, Nukina, N, Miyawaki, A. | Deposit date: | 2006-01-27 | Release date: | 2006-03-07 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The E1 mechanism in photo-induced beta-elimination reactions for green-to-red conversion of fluorescent proteins Chem.Biol., 16, 2009
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2DDC
| Unique behavior of a histidine responsible for an engineered green-to-red photoconversion process | Descriptor: | MAGNESIUM ION, SODIUM ION, photoconvertible fluorescent protein | Authors: | Shimizu, H, Tsutsui, H, Nukina, N, Miyawaki, A. | Deposit date: | 2006-01-27 | Release date: | 2006-03-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The E1 mechanism in photo-induced beta-elimination reactions for green-to-red conversion of fluorescent proteins. Chem.Biol., 16, 2009
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3ATW
| Structure-Based Design, Synthesis, Evaluation of Peptide-mimetic SARS 3CL Protease Inhibitors | Descriptor: | 3C-Like Proteinase, peptide ACE-THR-VAL-ALC-HIS-H | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-01-20 | Release date: | 2011-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AW0
| Structure of SARS 3CL protease with peptidic aldehyde inhibitor | Descriptor: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-LEU-HIS-H | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-03-09 | Release date: | 2011-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AW1
| Structure of SARS 3CL protease auto-proteolysis resistant mutant in the absent of inhibitor | Descriptor: | 3C-Like Proteinase | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-03-09 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AVZ
| Structure of SARS 3CL protease with peptidic aldehyde inhibitor containing cyclohexyl side chain | Descriptor: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-ALC-HIS-H | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | Deposit date: | 2011-03-09 | Release date: | 2011-12-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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1IU4
| Crystal Structure Analysis of the Microbial Transglutaminase | Descriptor: | microbial transglutaminase | Authors: | Kashiwagi, T, Yokoyama, K, Ishikawa, K, Ono, K, Ejima, D, Matsui, H, Suzuki, E. | Deposit date: | 2002-02-27 | Release date: | 2002-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense J.Biol.Chem., 277, 2002
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