5K4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4y by Molmil](/molmil-images/mine/5k4y) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei refined to 1.77 angstroms | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Adjogatse, E.A, Erskine, P.T, Cooper, J.B. | Deposit date: | 2016-05-22 | Release date: | 2018-01-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
|
|
5K4Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4q by Molmil](/molmil-images/mine/5k4q) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ refined to 2.3 angstroms | Descriptor: | GLYCEROL, L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Adjogatse, E.K, Cooper, J.B, Erskine, P.T. | Deposit date: | 2016-05-21 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
|
|
5K50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k50 by Molmil](/molmil-images/mine/5k50) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ and L-allo-threonine refined to 2.23 angstroms | Descriptor: | ACETATE ION, ALLO-THREONINE, GLYCEROL, ... | Authors: | Adjogatse, E.A, Erskine, P.T, Cooper, J.B. | Deposit date: | 2016-05-22 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
|
|
6AV9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6av9 by Molmil](/molmil-images/mine/6av9) | CryoEM structure of Mical Oxidized Actin (Class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | Deposit date: | 2017-09-01 | Release date: | 2018-01-17 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
|
|
6AVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6avb by Molmil](/molmil-images/mine/6avb) | CryoEM structure of Mical Oxidized Actin (Class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | Deposit date: | 2017-09-01 | Release date: | 2018-01-17 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
|
|
5K4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4w by Molmil](/molmil-images/mine/5k4w) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NADH and L-threonine refined to 1.72 angstroms | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-threonine 3-dehydrogenase, ... | Authors: | Adjogatse, E.A, Erskine, P.T, Cooper, J.B. | Deposit date: | 2016-05-22 | Release date: | 2018-01-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
|
|
5K4U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4u by Molmil](/molmil-images/mine/5k4u) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei showing different active site loop conformations between dimer subunits, refined to 1.9 angstroms | Descriptor: | ACETATE ION, GLYCEROL, L-threonine 3-dehydrogenase, ... | Authors: | Adjogatse, E.K, Cooper, J.B, Erskine, P.T. | Deposit date: | 2016-05-22 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
|
|
5K4T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4t by Molmil](/molmil-images/mine/5k4t) | |
5K4V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k4v by Molmil](/molmil-images/mine/5k4v) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ refined to 2.2 angstroms | Descriptor: | ACETATE ION, GLYCEROL, L-threonine 3-dehydrogenase, ... | Authors: | Adjogatse, E.A, Erskine, P.T, Cooper, J.B. | Deposit date: | 2016-05-22 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
|
|
5UBO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ubo by Molmil](/molmil-images/mine/5ubo) | Mical-oxidized Actin complex with Gelsolin Segment 1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Grintsevich, E.E, Sawaya, M.R, Reisler, E. | Deposit date: | 2016-12-21 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation. Nat Commun, 8, 2017
|
|
6E0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e0g by Molmil](/molmil-images/mine/6e0g) | Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein | Descriptor: | mitochondrial 2-cys-peroxiredoxin | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun, 10, 2019
|
|
6E0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e0f by Molmil](/molmil-images/mine/6e0f) | Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress | Descriptor: | mitochondrial 2-cys-peroxiredoxin | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun, 10, 2019
|
|
6OG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6og1 by Molmil](/molmil-images/mine/6og1) | Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, pre-state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Hyperactive disaggregase ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | Deposit date: | 2019-04-01 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nat Commun, 10, 2019
|
|
6OAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oax by Molmil](/molmil-images/mine/6oax) | Structure of the hyperactive ClpB mutant K476C, bound to casein, pre-state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Hyperactive disaggregase ClpB, ... | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | Deposit date: | 2019-03-18 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nat Commun, 10, 2019
|
|
6OAY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oay by Molmil](/molmil-images/mine/6oay) | Structure of the hyperactive ClpB mutant K476C, bound to casein, post-state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Hyperactive disaggregase ClpB, ... | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | Deposit date: | 2019-03-18 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nat Commun, 10, 2019
|
|
6OG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6og2 by Molmil](/molmil-images/mine/6og2) | Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, post-state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Hyperactive disaggregase ClpB | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | Deposit date: | 2019-04-01 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nat Commun, 10, 2019
|
|
6OG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6og3 by Molmil](/molmil-images/mine/6og3) | Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, NTD-trimer | Descriptor: | Alpha S1-casein, Hyperactive disaggregase ClpB | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | Deposit date: | 2019-04-01 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nat Commun, 10, 2019
|
|
8FCT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fct by Molmil](/molmil-images/mine/8fct) | Cryo-EM structure of p97:UBXD1 lariat mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fcp by Molmil](/molmil-images/mine/8fcp) | Cryo-EM structure of p97:UBXD1 para state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fcl by Molmil](/molmil-images/mine/8fcl) | Cryo-EM structure of p97:UBXD1 closed state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fcq by Molmil](/molmil-images/mine/8fcq) | Cryo-EM structure of p97:UBXD1 PUB-in state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fcr by Molmil](/molmil-images/mine/8fcr) | Cryo-EM structure of p97:UBXD1 H4-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (4.12 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fcm by Molmil](/molmil-images/mine/8fcm) | Cryo-EM structure of p97:UBXD1 open state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fco by Molmil](/molmil-images/mine/8fco) | Cryo-EM structure of p97:UBXD1 meta state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FCN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fcn by Molmil](/molmil-images/mine/8fcn) | Cryo-EM structure of p97:UBXD1 VIM-only state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 | Authors: | Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
|
|