289D
 
 | | TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2 | | Descriptor: | 2,5-BIS{[4-(N-CYCLOPROPYLDIAMINOMETHYL)PHENYL]}FURAN, DNA (5'-R(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | | Authors: | Trent, J.O, Clark, G.R, Kumar, A, Wilson, W.D, Boykin, D.W, Hall, J.E, Tidwell, R.R, Blagburn, B.L, Neidle, S. | | Deposit date: | 1996-10-10 | | Release date: | 1996-12-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2.
J.Med.Chem., 39, 1996
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298D
 | | TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2 | | Descriptor: | 2,5-BIS{[4-(N-ISOPROPYL)DIAMINOMETHYL]PHENYL}FURAN, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | | Authors: | Trent, J.O, Clark, G.R, Kumar, A, Wilson, W.D, Boykin, D.W, Hall, J.E, Tidwell, R.R, Blagburn, B.L, Neidle, S. | | Deposit date: | 1996-10-10 | | Release date: | 1996-12-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2.
J.Med.Chem., 39, 1996
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8DUT
 | | Duplex-G-quadruplex-duplex (DGD) class_1 | | Descriptor: | Duplex-G-quadruplex-duplex (46-MER) | | Authors: | Monsen, R.C, Chua, E.Y.D, Hopkins, J.B, Chaires, J.B, Trent, J.O. | | Deposit date: | 2022-07-27 | | Release date: | 2023-02-08 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 angstrom resolution with cryo-EM.
Nucleic Acids Res., 51, 2023
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6NUI
 | | Human Guanylate Kinase | | Descriptor: | Guanylate kinase | | Authors: | Sabo, T.M, Khan, N, Ban, D, Trigo-Mourino, P, Carneiro, M.G, Trent, J.O, Konrad, M, Lee, D. | | Deposit date: | 2019-02-01 | | Release date: | 2019-06-26 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.
J.Biol.Chem., 294, 2019
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1B3C
 | | SOLUTION STRUCTURE OF A BETA-NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING | | Descriptor: | PROTEIN (NEUROTOXIN CSE-I) | | Authors: | Jablonsky, M.J, Jackson, P.L, Trent, J.O, Watt, D.D, Krishna, N.R. | | Deposit date: | 1998-12-08 | | Release date: | 1998-12-16 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a beta-neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Biochem.Biophys.Res.Commun., 254, 1999
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1PCG
 | | Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions | | Descriptor: | ESTRADIOL, estrogen receptor, peptide inhibitor | | Authors: | Leduc, A.M, Trent, J.O, Wittliff, J.L, Bramlett, K.S, Briggs, S.L, Chirgadze, N.Y, Wang, Y, Burris, T.P, Spatola, A.F. | | Deposit date: | 2003-05-16 | | Release date: | 2003-10-28 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
Proc.Natl.Acad.Sci.USA, 100, 2003
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1OO7
 | | DNA.RNA HYBRID DUPLEX CONTAINING A 5-PROPYNE DNA STRAND AND PURINE-RICH RNA STRAND, NMR, 4 STRUCTURES | | Descriptor: | 5'-D(*GP*(5PC)P*(PDU)P*(PDU)P*(5PC)P*(PDU)P*(5PC)P*(PDU)P*(PDU)P*C)-3', 5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3' | | Authors: | Gyi, J.I, Gao, D, Conn, G.L, Trent, J.O, Brown, T, Lane, A.N. | | Deposit date: | 2003-03-03 | | Release date: | 2003-11-11 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications
Nucleic Acids Res., 31, 2003
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2KRR
 | | Solution structure of the RBD1,2 domains from human nucleolin | | Descriptor: | Nucleolin | | Authors: | Arumugam, N, Miller, C, Maliekal, J, Bates, P.J, Trent, J.O, Lane, A.N. | | Deposit date: | 2009-12-22 | | Release date: | 2010-05-05 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RBD1,2 domains from human nucleolin.
J.Biomol.Nmr, 47, 2010
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2B3C
 | | SOLUTION STRUCTURE OF A BETA-NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING | | Descriptor: | PROTEIN (NEUROTOXIN CSE-I) | | Authors: | Jablonsky, M.J, Jackson, P.L, Trent, J.O, Watt, D.D, Krishna, N.R. | | Deposit date: | 1998-12-09 | | Release date: | 1998-12-16 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a beta-neurotoxin from the New World scorpion Centruroides sculpturatus Ewing.
Biochem.Biophys.Res.Commun., 254, 1999
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252D
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