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PDB: 5 件

3S56
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BU of 3s56 by Molmil
HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug saquinavir
分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETATE ION, Protease
著者Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日2011-05-20
公開日2012-03-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors.
Protein Sci., 21, 2012
3S45
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BU of 3s45 by Molmil
wild-type HIV-2 protease with antiviral drug amprenavir
分子名称: CHLORIDE ION, IMIDAZOLE, Protease, ...
著者Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日2011-05-18
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors.
Protein Sci., 21, 2012
3S54
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BU of 3s54 by Molmil
HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, CHLORIDE ION, ...
著者Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日2011-05-20
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors.
Protein Sci., 21, 2012
3S53
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BU of 3s53 by Molmil
HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, IODIDE ION, PHOSPHATE ION, ...
著者Tie, Y.-F, Wang, Y.-F, Weber, I.T.
登録日2011-05-20
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors.
Protein Sci., 21, 2012
3S43
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BU of 3s43 by Molmil
HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug amprenavir
分子名称: GLYCEROL, IODIDE ION, Protease, ...
著者Wang, Y.-F, Tie, Y.-F, Weber, I.T.
登録日2011-05-18
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors.
Protein Sci., 21, 2012

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件を2024-11-06に公開中

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