3GWZ
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![BU of 3gwz by Molmil](/molmil-images/mine/3gwz) | Structure of the Mitomycin 7-O-methyltransferase MmcR | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, MmcR, ... | Authors: | Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S. | Deposit date: | 2009-04-01 | Release date: | 2010-04-07 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural characterization of the mitomycin 7-O-methyltransferase. Proteins, 79, 2011
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5DU2
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![BU of 5du2 by Molmil](/molmil-images/mine/5du2) | Structural analysis of EspG2 glycosyltransferase | Descriptor: | EspG2 glycosyltransferase | Authors: | Michalska, K, Elshahawi, S.I, Bigelow, L, Babnigg, G, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-09-18 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural analysis of EspG2 glycosyltransferase To Be Published
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1QZL
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![BU of 1qzl by Molmil](/molmil-images/mine/1qzl) | GCATGCT + Cobalt | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT (II) ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-17 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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3GXO
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![BU of 3gxo by Molmil](/molmil-images/mine/3gxo) | Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A | Descriptor: | CALCIUM ION, MmcR, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S. | Deposit date: | 2009-04-02 | Release date: | 2010-04-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural characterization of the mitomycin 7-O-methyltransferase. Proteins, 79, 2011
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1QYL
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![BU of 1qyl by Molmil](/molmil-images/mine/1qyl) | GCATGCT + Vanadium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', VANADIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be Published
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1QYK
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![BU of 1qyk by Molmil](/molmil-images/mine/1qyk) | GCATGCT + Barium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', BARIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1R2O
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![BU of 1r2o by Molmil](/molmil-images/mine/1r2o) | d(GCATGCT) + Ni2+ | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', NICKEL (II) ION | Authors: | Cardin, J.C, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-29 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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2LUZ
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![BU of 2luz by Molmil](/molmil-images/mine/2luz) | Solution NMR Structure of CalU16 from Micromonospora echinospora, Northeast Structural Genomics Consortium (NESG) Target MiR12 | Descriptor: | CalU16 | Authors: | Ramelot, T.A, Yang, Y, Lee, H, Pederson, K, Lee, D, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Wrobel, R.L, Bingman, C.A, Singh, S, Thorson, J.S, Prestegard, J.H, Montelione, G.T, Phillips Jr, G.N, Kennedy, M.A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-06-22 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19. Acs Chem.Biol., 9, 2014
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3PKP
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![BU of 3pkp by Molmil](/molmil-images/mine/3pkp) | Q83S Variant of S. Enterica RmlA with dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, MAGNESIUM ION | Authors: | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-11-11 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution. J.Biol.Chem., 286, 2011
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2HDL
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![BU of 2hdl by Molmil](/molmil-images/mine/2hdl) | Solution structure of Brak/CXCL14 | Descriptor: | Small inducible cytokine B14 | Authors: | Peterson, F.C, Thorpe, J.A, Harder, A.G, Volkman, B.F, Schwarze, S.R. | Deposit date: | 2006-06-20 | Release date: | 2006-10-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Determinants Involved in the Regulation of CXCL14/BRAK Expression by the 26 S Proteasome. J.Mol.Biol., 363, 2006
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4M60
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![BU of 4m60 by Molmil](/molmil-images/mine/4m60) | Crystal structure of macrolide glycosyltransferases OleD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Oleandomycin glycosyltransferase, SODIUM ION | Authors: | Olmos Jr, J.L, Martinez III, E, Wang, F, Helmich, K.E, Singh, S, Xu, W, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-08-08 | Release date: | 2013-09-04 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structure of macrolide glycosyltransferases OleD To be Published
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4M7P
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![BU of 4m7p by Molmil](/molmil-images/mine/4m7p) | Ensemble refinement of protein crystal structure of macrolide glycosyltransferases OleD | Descriptor: | Oleandomycin glycosyltransferase, SODIUM ION | Authors: | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-08-12 | Release date: | 2013-09-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structure of macrolide glycosyltransferases OleD To be Published
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1NT8
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![BU of 1nt8 by Molmil](/molmil-images/mine/1nt8) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 2.00 A | Descriptor: | 5'-d(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-01-29 | Release date: | 2003-02-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Analysis of two Holliday Junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1NVN
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![BU of 1nvn by Molmil](/molmil-images/mine/1nvn) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 1.8 A | Descriptor: | 5'-D(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Teixeira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-02-04 | Release date: | 2003-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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4LY7
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![BU of 4ly7 by Molmil](/molmil-images/mine/4ly7) | Ancestral RNase H | Descriptor: | Ribonuclease H, SULFATE ION | Authors: | Hart, K.M, Harms, M.J, Schmidt, B.H, Elya, C, Thornton, J.W, Marqusee, S. | Deposit date: | 2013-07-30 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Thermodynamic system drift in protein evolution. Plos Biol., 12, 2014
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1NQS
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![BU of 1nqs by Molmil](/molmil-images/mine/1nqs) | Structural Characterisation of the Holliday Junction formed by the sequence d(TCGGTACCGA) at 1.97 A | Descriptor: | 5'-d(TpCpGpGpTpApCpCpGpA)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-01-22 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural Analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1NVY
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![BU of 1nvy by Molmil](/molmil-images/mine/1nvy) | |
1FPW
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![BU of 1fpw by Molmil](/molmil-images/mine/1fpw) | STRUCTURE OF YEAST FREQUENIN | Descriptor: | CALCIUM ION, CALCIUM-BINDING PROTEIN NCS-1 | Authors: | Ames, J.B, Hendricks, K.B, Strahl, T, Huttner, I.G, Thorner, J. | Deposit date: | 2000-08-31 | Release date: | 2000-10-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae. Biochemistry, 39, 2000
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4XR9
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![BU of 4xr9 by Molmil](/molmil-images/mine/4xr9) | Crystal structure of CalS8 from Micromonospora echinospora cocrystallized with NAD and TDP-glucose | Descriptor: | CalS8, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-01-20 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of CalS8 from Micromonospora echinospora To Be Published
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3PKQ
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![BU of 3pkq by Molmil](/molmil-images/mine/3pkq) | Q83D Variant of S. Enterica RmlA with dGTP | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Glucose-1-phosphate thymidylyltransferase, ... | Authors: | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-11-11 | Release date: | 2011-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution. J.Biol.Chem., 286, 2011
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4PIW
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![BU of 4piw by Molmil](/molmil-images/mine/4piw) | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12 | Descriptor: | TDP-4-keto-6-deoxy-D-glucose transaminase family protein | Authors: | Wang, F, Xu, W, Helmich, K.E, Singh, S, Yennamalli, R.M, Miller, M.D, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-05-09 | Release date: | 2014-07-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12 To Be Published
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2L65
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![BU of 2l65 by Molmil](/molmil-images/mine/2l65) | HADDOCK calculated model of the complex of the resistance protein CalC and Calicheamicin-Gamma | Descriptor: | 2,4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-thio-beta-D-allopyranose, 3-O-methyl-alpha-L-rhamnopyranose, ... | Authors: | Singh, S, Markley, J.L, Thorson, J.S, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2010-11-15 | Release date: | 2011-03-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chem.Biol., 1, 2006
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4Q31
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![BU of 4q31 by Molmil](/molmil-images/mine/4q31) | The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ... | Authors: | Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-04-10 | Release date: | 2014-05-07 | Last modified: | 2017-03-08 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Struct Dyn, 3, 2016
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3OTI
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![BU of 3oti by Molmil](/molmil-images/mine/3oti) | Crystal Structure of CalG3, Calicheamicin Glycostyltransferase, TDP and calicheamicin T0 bound form | Descriptor: | CHLORIDE ION, CalG3, Calicheamicin T0, ... | Authors: | Chang, A, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2010-09-11 | Release date: | 2010-12-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.597 Å) | Cite: | Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc.Natl.Acad.Sci.USA, 108, 2011
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2GKD
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![BU of 2gkd by Molmil](/molmil-images/mine/2gkd) | |