7RIT
| Drug-free A. baumannii MsbA | Descriptor: | ATP-dependent lipid A-core flippase | Authors: | Thelot, F, Liao, M. | Deposit date: | 2021-07-20 | Release date: | 2021-10-06 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science, 374, 2021
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7R6L
| 5 prime exon-free pre-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | Descriptor: | Group I intron, 3 prime fragment plus 3 prime exon, 5 prime fragment, ... | Authors: | Thelot, F, Liu, D, Liao, M, Yin, P. | Deposit date: | 2021-06-22 | Release date: | 2022-05-04 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat.Methods, 19, 2022
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7R6N
| Exon-free state of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic trimeric construct | Descriptor: | Group I intron, MAGNESIUM ION | Authors: | Thelot, F, Liu, D, Liao, M, Yin, P. | Deposit date: | 2021-06-22 | Release date: | 2022-05-04 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat.Methods, 19, 2022
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7R6M
| Post-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | Descriptor: | Group I intron, Ligated exon mimic of the Group I intron, MAGNESIUM ION | Authors: | Thelot, F, Liu, D, Liao, M, Yin, P. | Deposit date: | 2021-06-22 | Release date: | 2022-05-04 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly. Nat.Methods, 19, 2022
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7MEW
| E. coli MsbA in complex with G247 | Descriptor: | (2E)-3-{1-cyclopropyl-7-[(1S)-1-(3,6-dichloro-2-fluorophenyl)ethoxy]naphthalen-2-yl}prop-2-enoic acid, ATP-dependent lipid A-core flippase | Authors: | Thelot, F, Liao, M. | Deposit date: | 2021-04-08 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science, 374, 2021
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7MET
| A. baumannii MsbA in complex with TBT1 decoupler | Descriptor: | 2-(4-chlorobenzamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid, ATP-dependent lipid A-core flippase | Authors: | Thelot, F, Liao, M. | Deposit date: | 2021-04-07 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science, 374, 2021
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