7R6R
 
 | | Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex | | Descriptor: | DNA (5'-D(P*CP*CP*CP*GP*CP*TP*TP*GP*AP*CP*AP*GP*CP*CP*AP*CP*CP*GP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*CP*GP*GP*TP*GP*GP*CP*TP*GP*TP*CP*AP*AP*GP*CP*GP*GP*G)-3'), Immunity repressor | | Authors: | McGinnis, R.J, Brambley, C.A, Stamey, B, Green, W.C, Gragg, K.N, Cafferty, E.R, Terwilliger, T.C, Hammel, M, Hollis, T.J, Miller, J.M, Gainey, M.D, Wallen, J.R. | | Deposit date: | 2021-06-23 | | Release date: | 2022-07-20 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.13 Å) | | Cite: | A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun, 13, 2022
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1VQJ
 | | GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 (V35I) | | Descriptor: | GENE V PROTEIN | | Authors: | Zhang, H, Skinner, M.M, Sandberg, W.S, Wang, A.H.-J, Terwilliger, T.C. | | Deposit date: | 1996-08-14 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Context dependence of mutational effects in a protein: the crystal structures of the V35I, I47V and V35I/I47V gene V protein core mutants.
J.Mol.Biol., 259, 1996
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1VQH
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8U21
 | | A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP E6 | | Descriptor: | Green Fluorescent Protein Variant E6, ccGFP E6 | | Authors: | Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. | | Deposit date: | 2023-09-05 | | Release date: | 2024-01-31 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
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8U24
 | | A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 9 | | Descriptor: | Green Fluorescent Protein Variant #9, ccGFP 9 | | Authors: | Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. | | Deposit date: | 2023-09-05 | | Release date: | 2024-01-31 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
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3TX8
 | | Crystal structure of a succinyl-diaminopimelate desuccinylase (ArgE) from Corynebacterium glutamicum ATCC 13032 at 2.97 A resolution | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase | | Authors: | Joint Center for Structural Genomics (JCSG), Brunger, A.T, Terwilliger, T.C, Read, R.J, Adams, P.D, Levitt, M, Schroder, G.F. | | Deposit date: | 2011-09-22 | | Release date: | 2011-10-26 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.972 Å) | | Cite: | Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.
Acta Crystallogr.,Sect.D, 68, 2012
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4LMP
 | | Mycobacterium tuberculosis L-alanine dehydrogenase x-ray structure in complex with N6-methyl adenosine | | Descriptor: | Alanine dehydrogenase, GLYCEROL, N-methyladenosine, ... | | Authors: | Kim, H.-B, Hung, L.-W, Goulding, C.W, Terwilliger, T.C, Kim, C.-Y, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | | Deposit date: | 2013-07-10 | | Release date: | 2013-11-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Drug target analysis by dye-ligand affinity chromatography
To be Published
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2MLT
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4P0M
 | | Crystal structure of an evolved putative penicillin-binding protein homolog, Rv2911, from Mycobacterium tuberculosis | | Descriptor: | D-alanyl-D-alanine carboxypeptidase | | Authors: | Krieger, I, Yu, M, Bursey, E, Hung, L.-W, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2014-02-21 | | Release date: | 2014-03-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Subfamily-Specific Adaptations in the Structures of Two Penicillin-Binding Proteins from Mycobacterium tuberculosis.
Plos One, 9, 2014
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1U5H
 | | Structure of Citrate Lyase beta subunit from Mycobacterium tuberculosis | | Descriptor: | FORMIC ACID, citE | | Authors: | Goulding, C.W, Lekin, T, Kim, C.Y, Segelke, B, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-07-27 | | Release date: | 2004-10-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J.Mol.Biol., 365, 2007
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4JJT
 | | The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv | | Descriptor: | ACETATE ION, Enoyl-CoA hydratase, GLYCEROL | | Authors: | Tan, K, Holowicki, J, Endres, M, Kim, C.-Y, Kim, H, Hung, L.-W, Terwilliger, T.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | | Deposit date: | 2013-03-08 | | Release date: | 2013-03-27 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.496 Å) | | Cite: | The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv
To be Published
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1YHB
 | | CRYSTAL STRUCTURES OF Y41H AND Y41F MUTANTS OF GENE V PROTEIN FROM FF PHAGE SUGGEST POSSIBLE PROTEIN-PROTEIN INTERACTIONS IN GVP-SSDNA COMPLEX | | Descriptor: | GENE V PROTEIN | | Authors: | Guan, Y, Zhang, H, Konings, R.N.H, Hilbers, C.W, Terwilliger, T.C, Wang, A.H.-J. | | Deposit date: | 1994-04-14 | | Release date: | 1994-06-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of Y41H and Y41F mutants of gene V protein from Ff phage suggest possible protein-protein interactions in the GVP-ssDNA complex.
Biochemistry, 33, 1994
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1YHA
 | | CRYSTAL STRUCTURES OF Y41H AND Y41F MUTANTS OF GENE V PROTEIN FROM FF PHAGE SUGGEST POSSIBLE PROTEIN-PROTEIN INTERACTIONS IN GVP-SSDNA COMPLEX | | Descriptor: | GENE V PROTEIN | | Authors: | Guan, Y, Zhang, H, Konings, R.N.H, Hilbers, C.W, Terwilliger, T.C, Wang, A.H.-J. | | Deposit date: | 1994-04-14 | | Release date: | 1994-06-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of Y41H and Y41F mutants of gene V protein from Ff phage suggest possible protein-protein interactions in the GVP-ssDNA complex.
Biochemistry, 33, 1994
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8U23
 | | A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 8 | | Descriptor: | Green Fluorescent Protein Variant #8, ccGFP 8 | | Authors: | Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. | | Deposit date: | 2023-09-05 | | Release date: | 2024-01-31 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
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8U20
 | | A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 5 | | Descriptor: | Green Fluorescent Protein Variant #5, ccGFP 5 | | Authors: | Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. | | Deposit date: | 2023-09-05 | | Release date: | 2024-01-31 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
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8U22
 | | A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 7 | | Descriptor: | Green Fluorescent Protein Variant #7, ccGFP 7 | | Authors: | Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. | | Deposit date: | 2023-09-05 | | Release date: | 2024-01-31 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Engineering highly stable variants of Corynactis californica green fluorescent proteins.
Protein Sci., 33, 2024
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4K7Q
 | | Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution | | Descriptor: | Acriflavine resistance protein B, N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide | | Authors: | Hung, L.W, Kim, H.B, Murakami, S, Gupta, G, Kim, C.Y, Terwilliger, T.C. | | Deposit date: | 2013-04-17 | | Release date: | 2013-07-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of AcrB complexed with linezolid at 3.5 Angstrom resolution.
J.Struct.Funct.Genom., 14, 2013
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4HB7
 | | The Structure of Dihydropteroate Synthase from Staphylococcus aureus subsp. aureus Mu50. | | Descriptor: | 1,2-ETHANEDIOL, Dihydropteroate synthase | | Authors: | Cuff, M.E, Holowicki, J, Jedrzejczak, R, Terwilliger, T.C, Rubin, E.J, Guinn, K, Baker, D, Ioerger, T.R, Sacchettini, J.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | | Deposit date: | 2012-09-27 | | Release date: | 2012-10-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Structure of Dihydropteroate Synthase from Staphylococcus aureus subsp. aureus Mu50.
TO BE PUBLISHED
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3LP6
 | | Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution | | Descriptor: | FORMIC ACID, GLYCEROL, Phosphoribosylaminoimidazole carboxylase catalytic subunit | | Authors: | Kim, H, Yu, M, Hung, L.-W, Terwilliger, T.C, Kim, C.-Y, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2010-02-04 | | Release date: | 2010-06-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A
Resolution
To be Published
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4KF5
 | | Crystal Structure of Split GFP complexed with engineered sfCherry with an insertion of GFP fragment | | Descriptor: | fluorescent protein GFP1-9, fluorescent protein sfCherry+GFP10-11 | | Authors: | Nguyen, H.B, Hung, L.-W, Yeates, T.O, Waldo, G.S, Terwilliger, T.C. | | Deposit date: | 2013-04-26 | | Release date: | 2013-12-18 | | Method: | X-RAY DIFFRACTION (2.599 Å) | | Cite: | Split green fluorescent protein as a modular binding partner for protein crystallization.
Acta Crystallogr.,Sect.D, 69, 2013
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4KF4
 | | Crystal Structure of sfCherry | | Descriptor: | fluorescent protein sfCherry | | Authors: | Nguyen, H.B, Hung, L.-W, Yeates, T.O, Waldo, G.S, Terwilliger, T.C. | | Deposit date: | 2013-04-26 | | Release date: | 2013-12-18 | | Method: | X-RAY DIFFRACTION (1.994 Å) | | Cite: | Split green fluorescent protein as a modular binding partner for protein crystallization.
Acta Crystallogr.,Sect.D, 69, 2013
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2FGG
 | | Crystal Structure of Rv2632c | | Descriptor: | Hypothetical protein Rv2632c/MT2708 | | Authors: | Yu, M, Bursey, E.H, Radhakannan, T, Segelke, B.W, Lekin, T, Toppani, D, Kim, C.Y, Kaviratne, T, Woodruff, T, Terwilliger, T.C, Hung, L.W, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2005-12-21 | | Release date: | 2006-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Rv2632c
To be Published
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2FSX
 | | Crystal structure of Rv0390 from M. tuberculosis | | Descriptor: | BROMIDE ION, COG0607: Rhodanese-related sulfurtransferase, SULFATE ION | | Authors: | Bursey, E.H, Radhakannan, T, Yu, M, Segelke, B.W, Lekin, T, Toppani, D, Chang, Y.-B, Kaviratne, T, Woodruff, T, Terwilliger, T.C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2006-01-23 | | Release date: | 2006-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Rv0390 from Mycobacterium tuberculosis
To be Published
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2FVH
 | | Crystal Structure of Rv1848, a Urease Gamma Subunit UreA (Urea amidohydrolase), from Mycobacterium Tuberculosis | | Descriptor: | Urease gamma subunit | | Authors: | Bursey, E.H, Yu, M, TB Structural Genomics Consortium (TBSGC), Lekin, T, Rupp, B, Kim, C.Y, Rho, B.S, Terwilliger, T.C. | | Deposit date: | 2006-01-30 | | Release date: | 2006-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Rv1848, a Urease Gamma Subunit UreA (Urea amidohydrolase), from Mycobacterium Tuberculosis
To be Published
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2KHR
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