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PDB: 63 results
8SFJ
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BU of 8sfj by Molmil
WT CRISPR-Cas12a with a 10bp R-loop
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*AP*CP*TP*TP*AP*TP*CP*AP*CP*TP*AP*AP*AP*AP*GP*AP*TP*CP*GP*GP*AP*AP*G)-3'), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*T)-3'), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:WT CRISPR-Cas12a with a 10bp R-loop
To Be Published
8SFL
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BU of 8sfl by Molmil
WT CRISPR-Cas12a with a 15bp R-loop
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (40-MER), RNA (34-MER)
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:WT CRISPR-Cas12a with a 15bp R-loop
To Be Published
8SFO
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BU of 8sfo by Molmil
WT CRISPR-Cas12a with a 20bp R-loop and nontarget strand in the RuvC active site.
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (35-MER), DNA (40-MER), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:WT CRISPR-Cas12a with a 20bp R-loop and nontarget strand in the RuvC active site.
To Be Published
8SFQ
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BU of 8sfq by Molmil
WT CRISPR-Cas12a post nontarget strand-cleavage with the the RuvC active site exposed.
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (34-MER), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*T)-3'), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:WT CRISPR-Cas12a post nontarget strand-cleavage with the the RuvC active site exposed.
To Be Published
8SFN
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BU of 8sfn by Molmil
WT CRISPR-Cas12a with a 16bp R-loop and nontarget strand in the RuvC active site.
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (30-MER), DNA (31-MER), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:WT CRISPR-Cas12a with a 16bp R-loop and nontarget strand in the RuvC active site.
To Be Published
8SFP
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BU of 8sfp by Molmil
WT CRISPR-Cas12a with the target strand in the RuvC active site.
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (40-MER), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*TP*A)-3'), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:WT CRISPR-Cas12a with the target strand in the RuvC active site.
To Be Published
8SFI
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BU of 8sfi by Molmil
WT CRISPR-Cas12a with a 8bp R-loop
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*TP*TP*AP*TP*CP*AP*CP*TP*AP*AP*AP*AP*GP*AP*TP*CP*GP*GP*AP*AP*G)-3'), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*TP*A)-3'), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:WT CRISPR-Cas12a with a 8bp R-loop
To Be Published
8SFH
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BU of 8sfh by Molmil
WT CRISPR-Cas12a with a 5bp R-loop
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (32-MER), RNA (27-MER)
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:WT CRISPR-Cas12a with a 5bp R-loop
To Be Published
8SFR
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BU of 8sfr by Molmil
WT CRISPR-Cas12a post nontarget strand cleavage.
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (34-MER), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*T)-3'), ...
Authors:Strohkendl, I, Taylor, D.W.
Deposit date:2023-04-11
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:WT CRISPR-Cas12a post nontarget strand cleavage.
To Be Published
8S9V
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BU of 8s9v by Molmil
CRISPR-Cas type III-D effector complex bound to a self-target RNA in the pre-cleavage state
Descriptor: CRISPR RNA, Cas10, Cas7-2x, ...
Authors:Schwartz, E.A, Taylor, D.W.
Deposit date:2023-03-30
Release date:2024-04-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Nat Commun, 15, 2024
8S9X
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BU of 8s9x by Molmil
CRISPR-Cas type III-D effector complex bound to self-target RNA in a post-cleavage state
Descriptor: CRISPR RNA, Cas10, Cas7-2x, ...
Authors:Schwartz, E.A, Taylor, D.W.
Deposit date:2023-03-30
Release date:2024-04-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Nat Commun, 15, 2024
7JHY
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BU of 7jhy by Molmil
Type IV-B CRISPR Complex
Descriptor: Csf2 (Cas7), Csf4 (Cas11), RNA (31-MER)
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2020-07-21
Release date:2021-03-31
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of a type IV CRISPR-Cas ribonucleoprotein complex.
Iscience, 24, 2021
7L1F
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BU of 7l1f by Molmil
SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate
Descriptor: Non-structural protein 7, Non-structural protein 8, RNA (5'-R(P*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*UP*CP*UP*UP*AP*G)-3'), ...
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2020-12-14
Release date:2021-02-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication.
Mol.Cell, 81, 2021
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數據於2024-10-30公開中

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