4C1I
| Selective Inhibitors of PDE2, PDE9, and PDE10: Modulators of Activity of the Central Nervous System | 分子名称: | (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol, CGMP-DEPENDENT 3', 5'-CYCLIC PHOSPHODIESTERASE, ... | 著者 | Jorgensen, M, Kehler, J, Langgard, M, Svenstrup, N, Tagmose, L. | 登録日 | 2013-08-12 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Chapter 4: Selective Inhibitors of Pde2, Pde9, and Pde10: Modulators of Activity of the Central Nervous System To be Published
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7PQT
| Apo human Kv3.1 cryo-EM structure | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | 著者 | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | 登録日 | 2021-09-20 | 公開日 | 2022-08-17 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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7PQU
| Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563) | 分子名称: | 1-(4-methylphenyl)sulfonyl-N-(1,3-oxazol-2-ylmethyl)pyrrole-3-carboxamide, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1 | 著者 | Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W. | 登録日 | 2021-09-20 | 公開日 | 2022-08-17 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators. Pnas Nexus, 1, 2022
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8B9V
| Crystal structure of Lu AF82422 in complex with alpha-synuclein 110-120 | 分子名称: | Alpha-synuclein 110-120, Lu AF82422 Fab heavy chain, Lu AF82422 Fab light chain, ... | 著者 | Bjerregaard-Andersen, K, Carr, K, Krogh, B.O, Kallunki, P, Tagmose, L, David, L. | 登録日 | 2022-10-10 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of Lu AF82422 in complex with alpha-synuclein 110-120 To Be Published
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