2DY5
 
 | | Crystal structure of rat heme oxygenase-1 in complex with heme and 2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane | | 分子名称: | 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE, CHLORIDE ION, Heme oxygenase 1, ... | | 著者 | Sugishima, M, Takahashi, H, Fukuyama, K. | | 登録日 | 2006-09-06 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | X-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase
Biochemistry, 46, 2007
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2E7E
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1UBB
 | | Crystal structure of rat HO-1 in complex with ferrous heme | | 分子名称: | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Sakamoto, H, Higashimoto, Y, Noguchi, M, Fukuyama, K. | | 登録日 | 2003-04-03 | | 公開日 | 2003-09-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
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2ZXL
 | | Crystal structure of red chlorophyll catabolite reductase from Arabidopsis thaliana | | 分子名称: | Red chlorophyll catabolite reductase, chloroplastic, SODIUM ION, ... | | 著者 | Sugishima, M, Kitamori, Y, Fukuyama, K. | | 登録日 | 2008-12-29 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of red chlorophyll catabolite reductase: enlargement of the ferredoxin-dependent bilin reductase family
J.Mol.Biol., 389, 2009
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2ZXK
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3AGB
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3AGC
 | | F218V mutant of the substrate-bound red chlorophyll catabolite reductase from Arabidopsis thaliana | | 分子名称: | 3-{(2Z,3S,4S)-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-2-[(5R)-2-[(3-ethyl-5-formyl-4-methyl-1H-pyrrol-2-yl)methyl]-5-(methoxycarbonyl)-3-methyl-4-oxo-4,5-dihydrocyclopenta[b]pyrrol-6(1H)-ylidene]-4-methyl-3,4-dihydro-2H-pyrrol-3-yl}propanoic acid, Red chlorophyll catabolite reductase, chloroplastic, ... | | 著者 | Sugishima, M, Fukuyama, K. | | 登録日 | 2010-03-30 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of the substrate-bound forms of red chlorophyll catabolite reductase: implications for site-specific and stereospecific reaction
J.Mol.Biol., 402, 2010
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3AGA
 | | Crystal structure of RCC-bound red chlorophyll catabolite reductase from Arabidopsis thaliana | | 分子名称: | 3-{(2Z,3S,4S)-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-2-[(5R)-2-[(3-ethyl-5-formyl-4-methyl-1H-pyrrol-2-yl)methyl]-5-(methoxycarbonyl)-3-methyl-4-oxo-4,5-dihydrocyclopenta[b]pyrrol-6(1H)-ylidene]-4-methyl-3,4-dihydro-2H-pyrrol-3-yl}propanoic acid, Red chlorophyll catabolite reductase, chloroplastic, ... | | 著者 | Sugishima, M, Fukuyama, K. | | 登録日 | 2010-03-30 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of the substrate-bound forms of red chlorophyll catabolite reductase: implications for site-specific and stereospecific reaction
J.Mol.Biol., 402, 2010
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1ULX
 | | Partially photolyzed structure of CO-bound heme-heme oxygenase complex | | 分子名称: | CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2003-09-16 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
J.Mol.Biol., 341, 2004
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1VGI
 | | Crystal structure of xenon bound rat heme-heme oxygenase-1 complex | | 分子名称: | FORMIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2004-04-26 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
J.Mol.Biol., 341, 2004
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1UGU
 | | Crystal structure of PYP E46Q mutant | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | | 著者 | Sugishima, M, Tanimoto, Y, Hamada, N, Tokunaga, F, Fukuyama, K. | | 登録日 | 2003-06-19 | | 公開日 | 2004-08-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure of photoactive yellow protein (PYP) E46Q mutant at 1.2 A resolution suggests how Glu46 controls the spectroscopic and kinetic characteristics of PYP.
Acta Crystallogr.,Sect.D, 60, 2004
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1WOV
 | | Crystal structure of heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme | | 分子名称: | Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Hagiwara, Y, Zhang, X, Yoshida, T, Migita, C.T, Fukuyama, K. | | 登録日 | 2004-08-26 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of dimeric heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme.
Biochemistry, 44, 2005
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1WOW
 | | Crystal structure of heme oxygenase-2 from Synechocystis sp. PCC 6803 complexed with heme in ferrous form | | 分子名称: | Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Hagiwara, Y, Zhang, X, Yoshida, T, Migita, C.T, Fukuyama, K. | | 登録日 | 2004-08-26 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of dimeric heme oxygenase-2 from Synechocystis sp. PCC 6803 in complex with heme.
Biochemistry, 44, 2005
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1WE1
 | | Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC6803 in complex with heme | | 分子名称: | CHLORIDE ION, Heme oxygenase 1, ISOPROPYL ALCOHOL, ... | | 著者 | Sugishima, M, Migita, C.T, Zhang, X, Yoshida, T, Fukuyama, K. | | 登録日 | 2004-05-21 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC 6803 in complex with heme
Eur.J.Biochem., 271, 2004
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4QCD
 | | Neutron crystal structure of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin IXalpha at room temperature. | | 分子名称: | BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase, trideuteriooxidanium | | 著者 | Unno, M, Ishikawa-Suto, K, Ishihara, M, Hagiwara, Y, Sugishima, M, Wada, K, Fukuyama, K. | | 登録日 | 2014-05-10 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-03-20 | | 実験手法 | NEUTRON DIFFRACTION (1.932 Å), X-RAY DIFFRACTION | | 主引用文献 | Insights into the Proton Transfer Mechanism of a Bilin Reductase PcyA Following Neutron Crystallography.
J. Am. Chem. Soc., 137, 2015
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7CCY
 | | Crystal structure of the 2-iodoporphobilinogen-bound holo form of human hydroxymethylbilane synthase | | 分子名称: | 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | | 著者 | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | | 登録日 | 2020-06-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
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7CD0
 | | Crystal structure of the 2-iodoporphobilinogen-bound ES2 intermediate form of human hydroxymethylbilane synthase | | 分子名称: | 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | | 著者 | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | | 登録日 | 2020-06-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
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7CCZ
 | | Crystal structure of the ES2 intermediate form of human hydroxymethylbilane synthase | | 分子名称: | 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | | 著者 | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | | 登録日 | 2020-06-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
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7CCX
 | | Crystal structure of the holo form of human hydroxymethylbilane synthase | | 分子名称: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | | 著者 | Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M. | | 登録日 | 2020-06-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
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3I94
 | | Crystal structure of PcyA-biliverdin XIII alpha complex | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methy l]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Phycocyanobilin:ferredoxin oxidoreductase, SULFATE ION | | 著者 | Hagiwara, Y, Sugishima, M, Fukuyama, K. | | 登録日 | 2009-07-10 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA).
to be published
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3I8U
 | | Crystal structure of PcyA-181,182-dihydrobiliverdin complex | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methy l]-5-[(Z)-(4-ethyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Phycocyanobilin:ferredoxin oxidoreductase | | 著者 | Hagiwara, Y, Sugishima, M, Fukuyama, K. | | 登録日 | 2009-07-10 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA).
To be Published
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3I95
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5B4J
 | | Crystal structure of I86D mutant of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin (data 3) | | 分子名称: | BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase | | 著者 | Hagiwara, Y, Wada, K, Irikawa, T, Unno, M, Fukuyama, K, Sugishima, M. | | 登録日 | 2016-04-04 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
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5B4H
 | | Crystal structure of I86D mutant of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin (data 1) | | 分子名称: | BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase | | 著者 | Hagiwara, Y, Wada, K, Irikawa, T, Unno, M, Fukuyama, K, Sugishima, M. | | 登録日 | 2016-04-04 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
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5B4I
 | | Crystal structure of I86D mutant of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin (data 2) | | 分子名称: | BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase | | 著者 | Hagiwara, Y, Wada, K, Irikawa, T, Unno, M, Fukuyama, K, Sugishima, M. | | 登録日 | 2016-04-04 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | Atomic-resolution structure of the phycocyanobilin:ferredoxin oxidoreductase I86D mutant in complex with fully protonated biliverdin
FEBS Lett., 590, 2016
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