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PDB: 38 件
8VGH
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BU of 8vgh by Molmil
CryoEM structure of tryptase in complex with wild type anti-tryptase Fab E104.v1
分子名称: Fab E104.v1 heavy chain, Fab E104.v1 light chain, Tryptase alpha/beta-1
著者Kung, J.E, Johnson, M.C, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGJ
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BU of 8vgj by Molmil
CryoEM structure of tryptase in complex with engineered conformationally rigid anti-tryptase Fab E104.v1.4DS
分子名称: Fab E104.v1.4DS heavy chain, Fab E104.v1.4DS light chain, Tryptase alpha/beta-1
著者Kung, J.E, Johnson, M.C, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGI
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BU of 8vgi by Molmil
CryoEM structure of tryptase in complex with engineered conformationally rigid anti-tryptase Fab E104.v1.2DS
分子名称: Fab E104.v1.2DS heavy chain, Fab E104.v1.2DS light chain, Tryptase alpha/beta-1
著者Kung, J.E, Johnson, M.C, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGK
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BU of 8vgk by Molmil
CryoEM structure of tryptase in complex with engineered conformationally rigid anti-tryptase Fab E104.v1.6DS
分子名称: Fab E104.v1.6DS light chain, Tryptase alpha/beta-1
著者Kung, J.E, Johnson, M.C, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGL
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BU of 8vgl by Molmil
CryoEM structure of Nav1.7 in complex with wild type Fab 7A9
分子名称: Chimeric Nav1.7-NavAb, Fab 7A9 heavy chain, Fab 7A9 light chain
著者Kung, J.E, Jao, C.C, Arthur, C.P, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VEG
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BU of 8veg by Molmil
Crystal structure of an engineered conformationally rigid anti-Tryptase Fab variant E104.v1.4DS.S112F
分子名称: Fab E104.v1.4DS.S112F heavy chain, Fab E104.v1.4DS.S112F light chain
著者Kung, J.E, Sudhamsu, J.
登録日2023-12-18
公開日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM
Biorxiv, 2024
8VGF
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BU of 8vgf by Molmil
Crystal structure of an engineered conformationally rigid anti-Tryptase Fab variant E104.v1.5DS
分子名称: Fab E104.v1.5DS heavy chain, Fab E104.v1.5DS light chain
著者Kung, J.E, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGG
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BU of 8vgg by Molmil
Crystal structure of an engineered conformationally rigid anti-Tryptase Fab variant E104.v1.6DS
分子名称: Fab E104.v1.6DS heavy chain, Fab E104.v1.6DS light chain
著者Kung, J.E, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGE
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BU of 8vge by Molmil
Crystal structure of an engineered conformationally rigid anti-Tryptase Fab variant E104.v1.4DS.A114F
分子名称: Fab E104.v1.4DS.A114F heavy chain, Fab E104.v1.4DS.A114F light chain
著者Kung, J.E, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGM
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BU of 8vgm by Molmil
CryoEM structure of Nav1.7 in complex with engineered conformationally rigid Fab 7A9.4DS
分子名称: Chimeric Nav1.7-NavAb, Fab 7A9.4DS heavy chain, Fab 7A9.4DS light chain
著者Kung, J.E, Jao, C.C, Arthur, C.P, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGQ
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BU of 8vgq by Molmil
CryoEM structure of GNE-1952-alkylated KRAS G12C in complex with engineered conformationally rigid Fab 2H11.4DS
分子名称: 1-{4-[(7M)-6-methyl-7-(5-methyl-2H-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl}propan-1-one, Fab 2H11.4DS heavy chain, Fab 2H11.4DS light chain, ...
著者Kung, J.E, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8VGP
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BU of 8vgp by Molmil
CryoEM structure of Angiopoietin-2 in complex with engineered conformationally rigid Fab 5A12.6DS
分子名称: Angiopoietin-2, CALCIUM ION, Fab 5A12.6DS heavy chain, ...
著者Kung, J.E, Sudhamsu, J.
登録日2023-12-27
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
8TJT
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BU of 8tjt by Molmil
The Fab fragment of an anti-glucagon receptor (GCGR) antibody
分子名称: anti-GCGR Fab heavy chain, anti-GCGR Fab light chain
著者Dai, J, Carter, P.J, Sudhamsu, J, Kung, J.
登録日2023-07-24
公開日2024-02-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG 1 antibody.
Mabs, 16, 2024
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件を2024-10-30に公開中

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