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PDB: 300 results

6UEX
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BU of 6uex by Molmil
Crystal structure of S. aureus LcpA in complex with octaprenyl-pyrophosphate-GlcNAc
Descriptor: 2-(acetylamino)-2-deoxy-1-O-[(S)-hydroxy{[(S)-hydroxy{[(2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]oxy}phosphoryl]oxy}phosphoryl]-alpha-D-glucopyranose, GLYCEROL, Regulatory protein MsrR, ...
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2019-09-23
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
6UF6
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BU of 6uf6 by Molmil
Crystal structure of B. subtilis TagU
Descriptor: GLYCEROL, Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU, SULFATE ION
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2019-09-23
Release date:2020-01-29
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
6UF3
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BU of 6uf3 by Molmil
Crystal structure of B. subtilis TagV
Descriptor: Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2019-09-23
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
6UF5
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BU of 6uf5 by Molmil
Crystal structure of B. subtilis TagT
Descriptor: Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagT
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2019-09-23
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
6U2D
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BU of 6u2d by Molmil
PmtCD peptide exporter basket domain
Descriptor: ABC transporter ATP-binding protein, IODIDE ION, SULFATE ION
Authors:Zeytuni, N, Strynadka, N.C.J.
Deposit date:2019-08-19
Release date:2020-10-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
1EAI
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BU of 1eai by Molmil
COMPLEX OF ASCARIS CHYMOTRPSIN/ELASTASE INHIBITOR WITH PORCINE ELASTASE
Descriptor: PROTEIN (CHYMOTRYPSIN/ELASTASE ISOINHIBITOR 1), PROTEIN (ELASTASE)
Authors:Huang, K, Strynadka, N.C.J, Bernard, V.D, Peanasky, R.J, James, M.N.G.
Deposit date:1999-03-25
Release date:1999-04-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase.
Structure, 2, 1994
1ERO
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BU of 1ero by Molmil
X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID
Descriptor: (1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID, TEM-1 BETA-LACTAMASE
Authors:Ness, S, Martin, R, Kindler, A.M, Paetzel, M, Gold, M, Jones, J.B, Strynadka, N.C.J.
Deposit date:2000-04-06
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).
Biochemistry, 39, 2000
5WC3
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BU of 5wc3 by Molmil
SpoIIIAG
Descriptor: SpoIIIAG, Stage III sporulation engulfment assemblyprotein
Authors:Zeytuni, N, Hong, C, Worrall, L.J, Huang, R.K, Yu, Z, Strynadka, N.C.J.
Deposit date:2017-06-29
Release date:2017-08-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in Bacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1KN9
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BU of 1kn9 by Molmil
CRYSTAL STRUCTURE OF A BACTERIAL SIGNAL PEPTIDASE APO-ENZYME, IMPLICATIONS FOR SIGNAL PEPTIDE BINDING AND THE SER-LYS DYAD MECHANISM.
Descriptor: Signal peptidase I
Authors:Paetzel, M, Dalbey, R.E, Strynadka, N.C.J.
Deposit date:2001-12-18
Release date:2002-01-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
J.Biol.Chem., 277, 2002
8V31
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BU of 8v31 by Molmil
Structure of Alistipes sp. 3-Keto-2-hydroxy-glucal-hydratase AL2
Descriptor: Glycosyl hydrolase, MAGNESIUM ION
Authors:Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2023-11-25
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An alternative broad-specificity pathway for glycan breakdown in bacteria
To Be Published
6PEP
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BU of 6pep by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgIJ from the Salmonella SPI-1 injectisome needle complex
Descriptor: Protein InvG, Protein PrgH, Protein PrgI, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6PEE
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BU of 6pee by Molmil
InvG secretin domain beta-barrel from Salmonella SPI-1 injectisome NC-base
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Protein InvG
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6PEM
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BU of 6pem by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q15
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BU of 6q15 by Molmil
Structure of the Salmonella SPI-1 injectisome needle complex
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q14
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BU of 6q14 by Molmil
Structure of the Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q16
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BU of 6q16 by Molmil
Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
8VA1
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BU of 8va1 by Molmil
S. aureus TarL H300N in complex with CDP-ribitol (single tetramer)
Descriptor: CDP-ribitol, Teichoic acid ribitol-phosphate polymerase TarL
Authors:Li, F.K.K, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2023-12-10
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
8VBW
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BU of 8vbw by Molmil
Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form
Descriptor: (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1
Authors:Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J.
Deposit date:2023-12-12
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
8VBV
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BU of 8vbv by Molmil
Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Cephalexin) inhibited form
Descriptor: (2S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 1
Authors:Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J.
Deposit date:2023-12-12
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
8V34
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BU of 8v34 by Molmil
Crystal structure of S. aureus TarK N-terminal domain
Descriptor: CDP-glycerol glycerophosphotransferase family protein
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2023-11-26
Release date:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
8VBT
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BU of 8vbt by Molmil
Structure of the monofunctional Staphylococcus aureus PBP1 in its apo form
Descriptor: Penicillin-binding protein 1
Authors:Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J.
Deposit date:2023-12-12
Release date:2024-05-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
8V33
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BU of 8v33 by Molmil
Crystal structure of S. aureus TarL N-terminal domain
Descriptor: SUCCINIC ACID, Teichoic acid ribitol-phosphate polymerase TarL
Authors:Li, F.K.K, Strynadka, N.C.J.
Deposit date:2023-11-26
Release date:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
8VBU
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BU of 8vbu by Molmil
Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Oxacillin) inhibited form
Descriptor: (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Penicillin-binding protein 1
Authors:Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J.
Deposit date:2023-12-12
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
6N7O
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BU of 6n7o by Molmil
Crystal structure of GIL01 gp7
Descriptor: GIL01 gp7, IODIDE ION
Authors:Caveney, N.A, Strynadka, N.C.J.
Deposit date:2018-11-27
Release date:2019-05-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor.
Structure, 27, 2019
6NJO
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BU of 6njo by Molmil
Structure of the assembled ATPase EscN from the enteropathogenic E. coli (EPEC) type III secretion system
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J.
Deposit date:2019-01-03
Release date:2019-02-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019

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