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PDB: 283 results

6UU5
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BU of 6uu5 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked with GTP, UTP, CTP, and dinucleotide GpA for 30 minutes)
Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (5.403 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU9
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BU of 6uu9 by Molmil
E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes)
Descriptor: 2',3'-DIDEOXYADENOSINE-5'-MONOPHOSPHATE, DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (5.4 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU4
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BU of 6uu4 by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.305 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU2
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BU of 6uu2 by Molmil
E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.404 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UTV
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BU of 6utv by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP, UTP, GTP, and ddATP for 150 seconds)
Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UUA
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BU of 6uua by Molmil
E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.002 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU3
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BU of 6uu3 by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.002 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU0
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BU of 6uu0 by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
364D
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BU of 364d by Molmil
3.0 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA
Descriptor: MAGNESIUM ION, RNA (5'-R(*CP*CP*CP*CP*AP*UP*GP*CP*GP*AP*GP*AP*GP*UP*AP*GP*G P*GP*AP*AP*CP*UP*GP*CP*CP*AP*GP*GP*CP*AP*U)-3'), RNA (5'-R(*CP*CP*GP*AP*UP*GP*GP*UP*AP*GP*UP*GP*UP*GP*GP*GP*G *UP*C)-3'), ...
Authors:Correll, C.C, Freeborn, B, Moore, P.B, Steitz, T.A.
Deposit date:1997-12-08
Release date:1998-01-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain.
Cell(Cambridge,Mass.), 91, 1997
1EFG
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BU of 1efg by Molmil
THE CRYSTAL STRUCTURE OF ELONGATION FACTOR G COMPLEXED WITH GDP, AT 2.7 ANGSTROMS RESOLUTION
Descriptor: ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE
Authors:Czworkowski, J, Wang, J, Steitz, T.A, Moore, P.B.
Deposit date:1994-10-17
Release date:1995-02-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.
EMBO J., 13, 1994
1MSW
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BU of 1msw by Molmil
Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase
Descriptor: DNA-directed RNA polymerase, Non-Template DNA, RNA message, ...
Authors:Yin, Y.W, Steitz, T.A.
Deposit date:2002-09-19
Release date:2002-11-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
Science, 298, 2002
2PZS
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BU of 2pzs by Molmil
Phi29 DNA polymerase complexed with primer-template DNA (post-translocation binary complex)
Descriptor: 5'-d(CTAACACGTAAGCAGTC)-3', 5'-d(GACTGCTTAC)-3', DNA polymerase
Authors:Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
Deposit date:2007-05-18
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2PY5
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BU of 2py5 by Molmil
Phi29 DNA polymerase complexed with single-stranded DNA
Descriptor: 1,2-ETHANEDIOL, 5'-d(GGACTTT)-3', DNA polymerase
Authors:Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
Deposit date:2007-05-15
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
1S76
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BU of 1s76 by Molmil
T7 RNA polymerase alpha beta methylene ATP elongation complex
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(P*GP*CP*CP*GP*TP*GP*CP*GP*CP*AP*TP*TP*CP*GP*CP*CP*GP*TP*GP*TP*T)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*GP*TP*TP*GP*CP*GP*CP*AP*CP*GP*GP*C)-3'), ...
Authors:Yin, Y.W, Steitz, T.A.
Deposit date:2004-01-29
Release date:2004-03-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:The structural mechanism of translocation and helicase activity in T7 RNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
2PYJ
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BU of 2pyj by Molmil
Phi29 DNA polymerase complexed with primer-template DNA and incoming nucleotide substrates (ternary complex)
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-d(ACACGTAAGCAGTC)-3', ...
Authors:Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
Deposit date:2007-05-16
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
1XHX
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BU of 1xhx by Molmil
Phi29 DNA Polymerase, orthorhombic crystal form
Descriptor: DNA polymerase, MAGNESIUM ION, SULFATE ION
Authors:Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
Deposit date:2004-09-21
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Mol.Cell, 16, 2004
1Q7Y
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BU of 1q7y by Molmil
Crystal Structure of CCdAP-Puromycin bound at the Peptidyl transferase center of the 50S ribosomal subunit
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1QVG
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BU of 1qvg by Molmil
Structure of CCA oligonucleotide bound to the tRNA binding sites of the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ...
Authors:Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-27
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
RNA, 9, 2003
1Q86
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BU of 1q86 by Molmil
Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit.
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into peptide bond formation.
Proc.Natl.Acad.Sci.USA, 99, 2002
1Q81
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BU of 1q81 by Molmil
Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit.
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Insights into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1Q82
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BU of 1q82 by Molmil
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1NOY
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BU of 1noy by Molmil
DNA POLYMERASE (E.C.2.7.7.7)/DNA COMPLEX
Descriptor: DNA (5'-D(*TP*TP*T)-3'), MANGANESE (II) ION, PROTEIN (DNA POLYMERASE (E.C.2.7.7.7)), ...
Authors:Wang, J, Yu, P, Lin, T.C, Konigsberg, W.H, Steitz, T.A.
Deposit date:1996-02-16
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions.
Biochemistry, 35, 1996
3CMA
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BU of 3cma by Molmil
The structure of CCA and CCA-Phe-Cap-Bio bound to the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Simonovic, M, Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
1QVF
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BU of 1qvf by Molmil
Structure of a deacylated tRNA minihelix bound to the E site of the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ...
Authors:Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-27
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
RNA, 9, 2003
1DFU
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BU of 1dfu by Molmil
CRYSTAL STRUCTURE OF E.COLI RIBOSOMAL PROTEIN L25 COMPLEXED WITH A 5S RRNA FRAGMENT AT 1.8 A RESOLUTION
Descriptor: 5S RRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN L25
Authors:Lu, M, Steitz, T.A.
Deposit date:1999-11-21
Release date:1999-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Escherichia coli ribosomal protein L25 complexed with a 5S rRNA fragment at 1.8-A resolution.
Proc.Natl.Acad.Sci.USA, 97, 2000

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