8EAT
 
 | | Yeast VO missing subunits a, e, and f in complex with Vma12-22p | | Descriptor: | V-type proton ATPase subunit F, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ... | | Authors: | Wang, H, Bueler, S.A, Rubinstein, J.L. | | Deposit date: | 2022-08-29 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7RJA
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8EAS
 | | Yeast VO in complex with Vma12-22p | | Descriptor: | V-type proton ATPase assembly factor Vma12p, V-type proton ATPase subunit F, V-type proton ATPase subunit a, ... | | Authors: | Wang, H, Bueler, S.A, Rubinstein, J.L. | | Deposit date: | 2022-08-29 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7RJE
 | | Complex III2 from Candida albicans, Inz-5 bound | | Descriptor: | 3-[2-fluoro-5-(trifluoromethyl)phenyl]-7-methyl-1-[(2-methyl-2H-tetrazol-5-yl)methyl]-1H-indazole, Cytochrome b, Cytochrome b-c1 complex subunit 2, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJD
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in c position | | Descriptor: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJC
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in intermediate position | | Descriptor: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJB
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in b position | | Descriptor: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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8EAU
 | | Yeast VO in complex with Vma21p | | Descriptor: | V-type proton ATPase subunit a, vacuolar isoform, V-type proton ATPase subunit c, ... | | Authors: | Wang, H, Bueler, S.A, Rubinstein, J.L. | | Deposit date: | 2022-08-29 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of V-ATPase V O region assembly by Vma12p, 21p, and 22p.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5I1M
 | | Yeast V-ATPase average of densities, a subunit segment | | Descriptor: | V-type proton ATPase subunit a, vacuolar isoform | | Authors: | Schep, D.G, Zhao, J, Rubinstein, J.L. | | Deposit date: | 2016-02-05 | | Release date: | 2016-03-09 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7MPE
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7Q21
 | | III2-IV2 respiratory supercomplex from Corynebacterium glutamicum | | Descriptor: | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | Authors: | Kovalova, T, Moe, A, Krol, S, Yanofsky, D.J, Bott, M, Sjostrand, D, Rubinstein, J.L, Hogbom, M, Brzezinski, P. | | Deposit date: | 2021-10-22 | | Release date: | 2022-02-02 | | Last modified: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The respiratory supercomplex from C. glutamicum.
Structure, 30, 2022
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6HWH
 | | Structure of a functional obligate respiratory supercomplex from Mycobacterium smegmatis | | Descriptor: | CARDIOLIPIN, COPPER (II) ION, Co-purified unknown peptide built as polyALA, ... | | Authors: | Wiseman, B, Nitharwal, R.G, Fedotovskaya, O, Schafer, J, Guo, H, Kuang, Q, Benlekbir, S, Sjostrand, D, Adelroth, P, Rubinstein, J.L, Brzezinski, P, Hogbom, M. | | Deposit date: | 2018-10-12 | | Release date: | 2018-11-07 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of a functional obligate complex III2IV2respiratory supercomplex from Mycobacterium smegmatis.
Nat. Struct. Mol. Biol., 25, 2018
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7LKF
 | | WT Chicken Scap L1-L7 / Fab 4G10 complex focused refinement | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4G10 heavy chain, 4G10 light chain, ... | | Authors: | Kober, D.L, Radhakrishnan, A, Goldstein, J.L, Brown, M.S, Clark, L.D, Bai, X.-C, Rosenbaum, D.M. | | Deposit date: | 2021-02-02 | | Release date: | 2021-06-30 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing.
Cell, 184, 2021
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7LKH
 | | Chicken Scap D435V L1-L7 domain / Fab complex focused map | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4G10 Fab heavy chain, 4G10 Fab kappa chain, ... | | Authors: | Kober, D.L, Radhakrishnan, A, Goldstein, J.L, Brown, M.S, Clark, L.D, Bai, X.-C, Rosenbaum, D.M. | | Deposit date: | 2021-02-02 | | Release date: | 2021-06-30 | | Last modified: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing.
Cell, 184, 2021
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7MD2
 | | The F1 region of ammocidin-bound Saccharomyces cerevisiae ATP synthase | | Descriptor: | (3~{E},5~{Z},7~{E},9~{R},10~{S},11~{E},13~{E},15~{E},17~{R},18~{S},20~{S})-20-[(1~{R})-1-[(2~{S},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},4~{S},5~{S},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-4-oxidanyl-oxan-2-yl]oxy-3-methoxy-6-(3-methoxypropyl)-5-methyl-2,4-bis(oxidanyl)oxan-2-yl]ethyl]-5,18-dimethoxy-3,7,9,11,13,15-hexamethyl-10-[(2~{R},3~{S},4~{R},5~{R},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13,15-hexaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... | | Authors: | Guo, H, Rubinstein, J.L. | | Deposit date: | 2021-04-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Biorxiv, 2021
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7MD3
 | | The F1 region of apoptolidin-bound Saccharomyces cerevisiae ATP synthase | | Descriptor: | (3~{E},5~{E},7~{E},9~{R},10~{R},11~{E},13~{E},17~{S},18~{S},20~{S})-18-methoxy-20-[(~{R})-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(2~{R})-3-methoxy-2-[(2~{R},4~{S},5~{S},6~{S})-5-[(2~{S},4~{R},5~{R},6~{R})-4-methoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4,6-dimethyl-4-oxidanyl-oxan-2-yl]oxy-propyl]-3,5-dimethyl-2,4-bis(oxidanyl)oxan-2-yl]-oxidanyl-methyl]-10-[(2~{R},3~{S},4~{S},5~{R},6~{S})-5-methoxy-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-3,5,7,9,13-pentamethyl-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... | | Authors: | Guo, H, Rubinstein, J.L. | | Deposit date: | 2021-04-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Biorxiv, 2021
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6B8H
 | | Mosaic model of yeast mitochondrial ATP synthase monomer | | Descriptor: | AATP synthase subunit g, ATP synthase catalytic sector F1 epsilon subunit, ATP synthase protein 8, ... | | Authors: | Guo, H, Bueler, S.A, Rubinstein, J.L. | | Deposit date: | 2017-10-07 | | Release date: | 2018-01-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Atomic model for the dimeric FO region of mitochondrial ATP synthase.
Science, 358, 2017
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6B2Z
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6BTM
 | | Structure of Alternative Complex III from Flavobacterium johnsoniae (Wild Type) | | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, Alternative Complex III subunit A, Alternative Complex III subunit B, ... | | Authors: | Sun, C, Benlekbir, S, Venkatakrishnan, P, Yuhang, W, Tajkhorshid, E, Rubinstein, J.L, Gennis, R.B. | | Deposit date: | 2017-12-07 | | Release date: | 2018-05-09 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the alternative complex III in a supercomplex with cytochrome oxidase.
Nature, 557, 2018
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6N2D
 | | Bacillus PS3 ATP synthase membrane region | | Descriptor: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit c | | Authors: | Guo, H, Rubinstein, J.L. | | Deposit date: | 2018-11-12 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of a bacterial ATP synthase.
Elife, 8, 2019
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6N2Y
 | | Bacillus PS3 ATP synthase class 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Guo, H, Rubinstein, J.L. | | Deposit date: | 2018-11-14 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of a bacterial ATP synthase.
Elife, 8, 2019
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6N2Z
 | | Bacillus PS3 ATP synthase class 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | Authors: | Guo, H, Rubinstein, J.L. | | Deposit date: | 2018-11-14 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of a bacterial ATP synthase.
Elife, 8, 2019
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5ARH
 | | Bovine mitochondrial ATP synthase state 2a | | Descriptor: | ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... | | Authors: | Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. | | Deposit date: | 2015-09-24 | | Release date: | 2015-10-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
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5ARA
 | | Bovine mitochondrial ATP synthase state 1a | | Descriptor: | ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... | | Authors: | Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. | | Deposit date: | 2015-09-24 | | Release date: | 2015-10-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
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5ARI
 | | Bovine mitochondrial ATP synthase state 2b | | Descriptor: | ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... | | Authors: | Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. | | Deposit date: | 2015-09-24 | | Release date: | 2015-10-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
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