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PDB: 238 件

4JCD
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S268Y Variant of JC Polyomavirus Major Capsid Protein VP1
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1
著者Stehle, T, Stroh, L.J.
登録日2013-02-21
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Progressive multifocal leukoencephalopathy-associated mutations in the JC polyomavirus capsid disrupt lactoseries tetrasaccharide c binding.
MBio, 4, 2013
4K6U
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Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386
分子名称: 3,3',3''-[nitrilotris(methanediyl-1H-1,2,3-triazole-4,1-diyl)]tripropan-1-ol, ACETATE ION, Fiber protein, ...
著者Stehle, T, Bauer, J.
登録日2013-04-16
公開日2014-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
Org.Biomol.Chem., 13, 2015
7NKT
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RBD domain of SARS-CoV2 in complex with neutralizing nanobody NM1226
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
著者Ostertag, E, Zocher, G, Stehle, T.
登録日2021-02-18
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies.
Embo Rep., 22, 2021
1CKL
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N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Casasnovas, J, Larvie, M, Stehle, T.
登録日1999-04-22
公開日1999-06-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of two CD46 domains reveals an extended measles virus-binding surface.
EMBO J., 18, 1999
2WY3
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Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands
分子名称: 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Mueller, S, Zocher, G, Steinle, A, Stehle, T.
登録日2009-11-11
公開日2010-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the Hcmv Ul16-Micb Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse Nkg2D Ligands.
Plos Pathog., 6, 2010
6QJU
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Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with 3-bromo-1H-indazol-5-amine
分子名称: 1,2-ETHANEDIOL, 3-bromanyl-2~{H}-indazol-5-amine, Bromodomain-containing protein 3, ...
著者Braun, M.B, Stehle, T, Heidrich, J.
登録日2019-01-25
公開日2020-02-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.202 Å)
主引用文献Br-O-modomain (BRD3) halogen binding to a small molecule
To Be Published
1CN3
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INTERACTION OF POLYOMAVIRUS INTERNAL PROTEIN VP2 WITH MAJOR CAPSID PROTEIN VP1 AND IMPLICATIONS FOR PARTICIPATION OF VP2 IN VIRAL ENTRY
分子名称: COAT PROTEIN VP1, FRAGMENT OF COAT PROTEIN VP2
著者Chen, X, Stehle, T, Harrison, S.C.
登録日1999-05-24
公開日1999-06-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry.
EMBO J., 17, 1998
7PAA
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JC polyomavirus VP1 in complex with scFv 29B1
分子名称: Major capsid protein VP1, scFv 29B1
著者Harprecht, C, Stroeh, L.J, Freytag, J, Stehle, T.
登録日2021-07-29
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural characterization of human neutralizing antibodies against JC and BK polyomavirus
To Be Published
7PA7
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BK polyomavirus VP1 in complex with scFv 29B1
分子名称: Major capsid protein VP1, scFv 29B1 antibody heavy chain
著者Harprecht, C, Stroeh, L.J, Freytag, J, Stehle, T.
登録日2021-07-29
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural characterization of human neutralizing antibodies against JC and BK polyomavirus
To Be Published
7QB5
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Coxsackievirus A24v (CVA24v) in complex with a dimeric C2-C9-linked sialic acid inhibitor
分子名称: CALCIUM ION, CHLORIDE ION, Capsid protein VP1, ...
著者Zocher, G, Stehle, T.
登録日2021-11-18
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.728 Å)
主引用文献Exploring divalent conjugates of 5- N -acetyl-neuraminic acid as inhibitors of coxsackievirus A24 variant (CVA24v) transduction.
Rsc Adv, 12, 2022
5EFV
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The host-recognition device of Staphylococcus aureus phage Phi11
分子名称: FE (III) ION, Phi ETA orf 56-like protein
著者Koc, C, Kuhner, P, Xia, G, Spinelli, S, Roussel, A, Cambillau, C, Stehle, T.
登録日2015-10-26
公開日2016-05-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the host-recognition device of Staphylococcus aureus phage 11.
Sci Rep, 6, 2016
6TSD
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Crystal structure of human coxsackievirus A24v in complex with pentavalent inhibitor ME0752
分子名称: CALCIUM ION, CHLORIDE ION, Capsid protein VP1, ...
著者Zocher, G, Stehle, T.
登録日2019-12-20
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Pentavalent Sialic Acid Conjugates Block Coxsackievirus A24 Variant and Human Adenovirus Type 37-Viruses That Cause Highly Contagious Eye Infections.
Acs Chem.Biol., 15, 2020
4U62
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Trichodysplasia spinulosa-associated polyomavirus (TSPyV) VP1 in complex with 3'-sialyllactose
分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-acetyl-alpha-neuraminic acid, ...
著者Stroh, L.J, Stehle, T.
登録日2014-07-26
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids.
Plos Pathog., 11, 2015
4U5Z
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Trichodysplasia spinulosa-associated polyomavirus (TSPyV) VP1
分子名称: Structural protein VP1
著者Stroh, L.J, Stehle, T.
登録日2014-07-26
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids.
Plos Pathog., 11, 2015
4U61
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Trichodysplasia spinulosa-associated polyomavirus (TSPyV) VP1 in complex with 6'-sialyllactose
分子名称: GLYCEROL, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ...
著者Stroh, L.J, Stehle, T.
登録日2014-07-26
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids.
Plos Pathog., 11, 2015
4U60
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Trichodysplasia spinulosa-associated polyomavirus (TSPyV) VP1 in complex with GM1 oligosaccharide
分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-acetyl-alpha-neuraminic acid, ...
著者Stroh, L.J, Stehle, T.
登録日2014-07-26
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids.
Plos Pathog., 11, 2015
4XC5
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CRYSTAL STRUCTURE OF THE T1L REOVIRUS ATTACHMENT PROTEIN SIGMA1
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Reiss, K, Stehle, T.
登録日2014-12-17
公開日2015-04-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Serotype 1 Reovirus Attachment Protein sigma 1 in Complex with Junctional Adhesion Molecule A Reveals a Conserved Serotype-Independent Binding Epitope.
J.Virol., 89, 2015
7QNT
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TarM(Se) native
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Guo, Y, Stehle, T.
登録日2021-12-22
公開日2023-05-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition.
Sci Adv, 9, 2023
2BDJ
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Src kinase in complex with inhibitor AP23464
分子名称: 3-[2-(2-CYCLOPENTYL-6-{[4-(DIMETHYLPHOSPHORYL)PHENYL]AMINO}-9H-PURIN-9-YL)ETHYL]PHENOL, Proto-oncogene tyrosine-protein kinase Src
著者Dalgarno, D, Stehle, T, Schelling, P, Narula, S, Sawyer, T.
登録日2005-10-20
公開日2006-10-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Chem.Biol.Drug Des., 67, 2006
2BDF
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Src kinase in complex with inhibitor AP23451
分子名称: Proto-oncogene tyrosine-protein kinase Src, {[(4-{[2-(4-AMINOCYCLOHEXYL)-9-ETHYL-9H-PURIN-6-YL]AMINO}PHENYL)(HYDROXY)PHOSPHORYL]METHYL}PHOSPHONIC ACID
著者Dalgarno, D, Stehle, T, Schelling, P, Sawyer, T, Narula, S.
登録日2005-10-20
公開日2006-10-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Chem.Biol.Drug Des., 67, 2006
1U8C
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A novel adaptation of the integrin PSI domain revealed from its crystal structure
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.P, Stehle, T, Goodman, S.L, Arnaout, M.A.
登録日2004-08-05
公開日2004-12-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A novel adaptation of the integrin PSI domain revealed from its crystal structure.
J.Biol.Chem., 279, 2004
8OW7
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Crystal structure of Tannerella forsythia sugar kinase K1058 in complex with N-acetylmuramic acid (MurNAc)
分子名称: N-acetyl-beta-muramic acid, N-acetylglucosamine kinase, SULFATE ION
著者Stasiak, A.C, Gogler, K, Fink, P, Stehle, T, Zocher, G.
登録日2023-04-27
公開日2023-08-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia.
J.Biol.Chem., 299, 2023
6Y67
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Structure of apo Finch Polyomavirus VP1
分子名称: CHLORIDE ION, Capsid protein VP1
著者Stroh, L.J, Rustmeier, N.H, Stehle, T.
登録日2020-02-26
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.618 Å)
主引用文献Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family.
Mbio, 11, 2020
8P20
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TarM(Se)_G117R-UDP-4RboP-glucose
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ...
著者Guo, Y, Stehle, T.
登録日2023-05-14
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition.
Sci Adv, 9, 2023
4WDY
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JC Polyomavirus VP1 five-fold pore mutant N221Q
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1
著者Stroh, L.J, Stehle, T.
登録日2014-09-09
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins.
J.Virol., 89, 2015

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