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PDB: 9 件

5EMZ
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BU of 5emz by Molmil
Crystal structure of K48-linked diubiquitin with F45W mutation in the proximal unit
分子名称: Polyubiquitin-B, SULFATE ION
著者Nakasone, M.A, Paukstelis, P.J, Fushman, D.
登録日2015-11-07
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural characterization and practical fluorescence applications of the F45W ubiquitin mutant
To Be Published
1X03
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BU of 1x03 by Molmil
Crystal structure of endophilin BAR domain
分子名称: SH3-containing GRB2-like protein 2
著者Masuda, M, Takeda, S, Sone, M, Kamioka, Y, Mori, H, Mochizuki, N.
登録日2005-03-14
公開日2006-05-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms
Embo J., 25, 2006
1X04
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BU of 1x04 by Molmil
Crystal structure of endophilin BAR domain (mutant)
分子名称: SH3-containing GRB2-like protein 2
著者Masuda, M, Takeda, S, Sone, M, Kamioka, Y, Mori, H, Mochizuki, N.
登録日2005-03-14
公開日2006-05-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms
Embo J., 25, 2006
5AHV
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BU of 5ahv by Molmil
Cryo-EM structure of helical ANTH and ENTH tubules on PI(4,5)P2-containing membranes
分子名称: ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2, ENTH DOMAIN OF EPSIN ENT1
著者Skruzny, M, Desfosses, A, Prinz, S, Dodonova, S.O, Gieras, A, Uetrecht, C, Jakobi, A.J, Abella, M, Hagen, W.J.H, Schulz, J, Meijers, R, Rybin, V, Briggs, J.A.G, Sachse, C, Kaksonen, M.
登録日2015-02-10
公開日2015-05-06
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (13.6 Å)
主引用文献An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
8RWZ
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BU of 8rwz by Molmil
Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Cullin-2, ...
著者Crowe, C, Nakasone, M.A, Ciulli, A.
登録日2024-02-05
公開日2024-03-06
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Mechanism of degrader-targeted protein ubiquitinability.
Sci Adv, 10, 2024
8RX0
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BU of 8rx0 by Molmil
(NEDD8)-CRL2VHL-MZ1-Brd4BD2-Ub(G76S, K48C)-UBE2R1(C93K, S138C, C191S, C223S)-Ub
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Crowe, C, Nakasone, M.A, Ciulli, A.
登録日2024-02-05
公開日2024-03-06
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanism of degrader-targeted protein ubiquitinability.
Sci Adv, 10, 2024
4OWP
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BU of 4owp by Molmil
Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.
分子名称: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, ZINC ION
著者Yu, Z, Mansour, W, Nakasone, M.A, Glickman, M.H, Dvir, H.
登録日2014-02-03
公開日2015-08-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.In preparation.
To Be Published
7OJX
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BU of 7ojx by Molmil
E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain synthesis
分子名称: 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), E3 ubiquitin-protein ligase RNF38, Polyubiquitin-B, ...
著者Majorek, K.A, Nakasone, M.A, Huang, D.T.
登録日2021-05-17
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension.
Nat.Chem.Biol., 18, 2022
4B2Z
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BU of 4b2z by Molmil
Structure of Osh6 in complex with phosphatidylserine
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
著者Maeda, K, Anand, K, Chiapparino, A, Kumar, A, Poletto, M, Kaksonen, M, Gavin, A.C.
登録日2012-07-19
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Interactome Map Uncovers Phosphatidylserine Transport by Oxysterol-Binding Proteins
Nature, 501, 2013

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件を2024-11-06に公開中

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