1R5H
 
 | | Crystal Structure of MetAP2 complexed with A320282 | | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-10 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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1YMH
 | | anti-HCV Fab 19D9D6 complexed with protein L (PpL) mutant A66W | | 分子名称: | Fab 16D9D6, heavy chain, light chain, ... | | 著者 | Granata, V, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A. | | 登録日 | 2005-01-21 | | 公開日 | 2005-05-31 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Comparison of the crystallization and crystal packing of two Fab single-site mutant protein L complexes.
Acta Crystallogr.,Sect.D, 61, 2005
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6V05
 | | Cryo-EM structure of a substrate-engaged Bam complex | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamA,Outer membrane protein assembly factor BamA,Outer membrane protein assembly factor BamA,Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | 著者 | Tomasek, D, Rawson, S, Lee, J, Wzorek, J.S, Harrison, S.C, Li, Z, Kahne, D. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of a nascent membrane protein as it folds on the BAM complex.
Nature, 583, 2020
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4R64
 | | Binary complex crystal structure of E295K mutant of DNA polymerase Beta | | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | | 著者 | Batra, V.K, Beard, W.A, Wilson, S.H. | | 登録日 | 2014-08-22 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
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2JAS
 | | Structure of deoxyadenosine kinase from M.mycoides with bound dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DEOXYGUANOSINE KINASE, MAGNESIUM ION | | 著者 | Welin, M, Wang, L, Eriksson, S, Eklund, H. | | 登録日 | 2006-11-30 | | 公開日 | 2007-01-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity.
J.Mol.Biol., 366, 2007
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1DZ5
 | | The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein | | 分子名称: | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | 著者 | Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. | | 登録日 | 2000-02-16 | | 公開日 | 2000-03-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
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5XZB
 | | Mouse cGAS bound to the inhibitor RU365 | | 分子名称: | (3R)-3-[1-(1H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-2-benzofuran-1(3H)-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... | | 著者 | Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. | | 登録日 | 2017-07-12 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice.
Nat Commun, 8, 2017
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2BS7
 | | Crystal structure of F17b-G in complex with chitobiose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, F17BG LECTIN | | 著者 | Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | | 登録日 | 2005-05-18 | | 公開日 | 2006-05-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Impact of Natural Variation in Bacterial F17G Adhesins on Crystallization Behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
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1GQ1
 | | CYTOCHROME CD1 NITRITE REDUCTASE, Y25S mutant, OXIDISED FORM | | 分子名称: | CYTOCHROME CD1 NITRITE REDUCTASE, GLYCEROL, HEME C, ... | | 著者 | Sjogren, T, Gordon, E.H.J, Lofqvist, M, Richter, C.D, Hajdu, J, Ferguson, S.J. | | 登録日 | 2001-11-19 | | 公開日 | 2002-11-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure and Kinetic Properties of Paracoccus Pantotrophus Cytochrome Cd1 Nitrite Reductase with the D1 Heme Active Site Ligand Tyrosine 25 Replaced by Serine
J.Biol.Chem., 278, 2003
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3PFU
 | | N-terminal domain of Thiol:disulfide interchange protein DsbD in its reduced form | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thiol:disulfide interchange protein dsbD | | 著者 | Mavridou, D.A.I, Saridakis, E, Ferguson, S.J, Redfield, C. | | 登録日 | 2010-10-29 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Oxidation state-dependent protein-protein interactions in disulfide cascades
J.Biol.Chem., 286, 2011
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4R66
 | | Ternary complex crystal structure of E295K mutant of DNA polymerase Beta | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | | 著者 | Batra, V.K, Beard, W.A, Wilson, S.H. | | 登録日 | 2014-08-22 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
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2BSB
 | | E. coli F17e-G lectin domain complex with N-acetylglucosamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G ADHESIN SUBUNIT | | 著者 | Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | | 登録日 | 2005-05-20 | | 公開日 | 2006-05-24 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Impact of Natural Variation in Bacterial F17G Adhesins on Crystallization Behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
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5DKU
 | | C-terminal His tagged apPOL exonuclease mutant | | 分子名称: | MAGNESIUM ION, Prex DNA polymerase | | 著者 | Milton, M.E, Honzatko, R.B, Choe, J.Y, Nelson, S.W. | | 登録日 | 2015-09-04 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase.
J.Mol.Biol., 428, 2016
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8RLF
 | | Hydrogenated hen egg-white lysozyme at room temperature | | 分子名称: | ACETATE ION, Lysozyme C, NITRATE ION | | 著者 | Ramos, J, Laux, V, Mason, S.A, Lemee, M, Bowler, M, Diederichs, K, Haertlein, M, Forsyth, V.T, Mossou, E, Larsen, S, Langkilde, A.E. | | 登録日 | 2024-01-03 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | Hydrogenated hen egg-white lysozyme at room temperature
To Be Published
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8RLH
 | | Neutron structure of hydrogenated hen egg-white lysozyme at room temperature | | 分子名称: | ACETATE ION, Lysozyme C, NITRATE ION | | 著者 | Ramos, J, Laux, V, Mason, S.A, Lemee, M, Bowler, M, Diederichs, K, Haertlein, M, Forsyth, V.T, Mossou, E, Larsen, S, Langkilde, A.E. | | 登録日 | 2024-01-03 | | 公開日 | 2024-11-06 | | 実験手法 | NEUTRON DIFFRACTION (1.1 Å) | | 主引用文献 | Neutron structure of hydrogenated hen egg-white lysozyme at room temperature
To Be Published
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8RLI
 | | Neutron structure of perdeuterated hen egg-white lysozyme at room temperature | | 分子名称: | ACETATE ION, Lysozyme C, NITRATE ION | | 著者 | Ramos, J, Laux, V, Mason, S.A, Lemee, M, Bowler, M, Diederichs, K, Haertlein, M, Forsyth, V.T, Mossou, E, Larsen, S, Langkilde, A.E. | | 登録日 | 2024-01-03 | | 公開日 | 2024-11-06 | | 実験手法 | NEUTRON DIFFRACTION (0.91 Å) | | 主引用文献 | Neutron structure of perdeuterated hen egg-white lysozyme at room temperature
To Be Published
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5DYN
 | | B. fragilis cysteine protease | | 分子名称: | CHLORIDE ION, Putative peptidase, SODIUM ION | | 著者 | Choi, V.M, Herrou, J, Hecht, A.L, Turner, J.R, Crosson, S, Bubeck Wardenburg, J. | | 登録日 | 2015-09-24 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice.
Nat. Med., 22, 2016
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5HPO
 | | Cycloalternan-forming enzyme from Listeria monocytogenes in complex with maltopentaose | | 分子名称: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Halavaty, A.S, Light, S.H, Minasov, G, Winsor, J, Grimshaw, S, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-01-20 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity.
Structure, 25, 2017
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5F9A
 | | Blood group antigen binding adhesin BabA of Helicobacter pylori strain P436 in complex with blood group H Lewis b hexasaccharide | | 分子名称: | Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H. | | 登録日 | 2015-12-09 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
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2BS8
 | | Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESIN | | 著者 | Buts, L, Wellens, A, VanMolle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, DeGreve, H, Bouckaert, J. | | 登録日 | 2005-05-18 | | 公開日 | 2005-08-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Impact of Natural Variation in Bacterial F17G Adhesins on Crystallization Behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
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5HXM
 | | Cycloalternan-forming enzyme from Listeria monocytogenes in complex with panose | | 分子名称: | Alpha-xylosidase, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Halavaty, A.S, Light, S.H, Minasov, G, Winsor, J, Grimshaw, S, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-01-31 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity.
Structure, 25, 2017
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1PZL
 | | Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide | | 分子名称: | Hepatocyte nuclear factor 4-alpha, MYRISTIC ACID, steroid receptor coactivator-1 | | 著者 | Duda, K, Chi, Y.-I, Dhe-paganon, S, Shoelson, S. | | 登録日 | 2003-07-11 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for HNF-4alpha Activation by Ligand and Coactivator Binding
J.Biol.Chem., 279, 2004
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2BSC
 | | E. coli F17a-G lectin domain complex with N-acetylglucosamine, high- resolution structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17A-G ADHESIN | | 著者 | Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | | 登録日 | 2005-05-20 | | 公開日 | 2006-05-24 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Impact of Natural Variation in Bacterial F17G Adhesins on Crystallization Behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
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1GXC
 | | FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide | | 分子名称: | SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE | | 著者 | Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | | 登録日 | 2002-04-02 | | 公開日 | 2002-06-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Mol.Cell, 9, 2002
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5W0D
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