7LZH
| Structure of the glutamate receptor-like channel AtGLR3.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-18 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZ1
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with serine | Descriptor: | GLYCEROL, Glutamate receptor 3.4, SERINE, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7LZ0
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with glutamate | Descriptor: | CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | Deposit date: | 2021-03-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
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7MIO
| Mouse TRPV3 in cNW11 nanodiscs, open state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIJ
| Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 4 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (1.98 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIK
| Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIL
| Mouse TRPV3 in MSP2N2 nanodiscs, sensitized state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIN
| Mouse TRPV3 in cNW11 nanodiscs, closed state at 42 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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7MIM
| Mouse TRPV3 in cNW11 nanodiscs, closed state at 4 degrees Celsius | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-04-17 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. Nat.Struct.Mol.Biol., 28, 2021
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6DVY
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6DM1
| Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction | Descriptor: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | Authors: | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | Deposit date: | 2018-06-04 | Release date: | 2018-08-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
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5VHX
| GluA2-1xGSG1L bound to ZK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-04-13 | Release date: | 2017-05-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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6D7P
| Crystal Structure of Rat TRPV6*-Y466A | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | Authors: | Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I. | Deposit date: | 2018-04-25 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB. Nat Commun, 9, 2018
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5VHY
| GluA2-2xGSG1L bound to ZK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-04-13 | Release date: | 2017-05-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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6DVZ
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5WEM
| GluA2 bound to GSG1L in digitonin, state 1 | Descriptor: | Chimera of Glutamate receptor 2,Germ cell-specific gene 1-like protein | Authors: | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | Deposit date: | 2017-07-10 | Release date: | 2017-08-02 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
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5WOA
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7RAS
| Structure of TRPV3 in complex with osthole | Descriptor: | 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-07-02 | Release date: | 2021-09-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structural mechanism of TRPV3 channel inhibition by the plant-derived coumarin osthole. Embo Rep., 22, 2021
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7RAU
| Structure of TRPV3 in complex with osthole | Descriptor: | 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-07-02 | Release date: | 2021-09-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structural mechanism of TRPV3 channel inhibition by the plant-derived coumarin osthole. Embo Rep., 22, 2021
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7RZA
| Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 | Authors: | Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2021-08-27 | Release date: | 2021-10-27 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.26 Å) | Cite: | Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
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7RZ6
| Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2 | Authors: | Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2021-08-27 | Release date: | 2021-10-27 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
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7RYZ
| Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2 | Authors: | Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2021-08-26 | Release date: | 2021-10-27 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
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7RYY
| Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2 | Authors: | Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2021-08-26 | Release date: | 2021-10-27 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
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7RZ5
| Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2021-08-27 | Release date: | 2021-10-27 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L. Mol.Cell, 81, 2021
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7RZ9
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